XNAS 15 Oct, 2026 10:36 AM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 60.00 per share. | 23 Sep 2026 | 4,519 | 142,745 (0%) | 0% | 60 | 271,140 | - |
| Ms. Regina E. Groves | Director | Sale of securities on an exchange or to another person at price $ 54.22 per share. | 11 Sep 2026 | 5,313 | 34,546 (0%) | 0% | 54.2 | 288,071 | Common Stock |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 55.00 per share. | 08 Sep 2026 | 3,657 | 147,264 (0%) | 0% | 55 | 201,135 | Common Stock |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 52.50 per share. | 02 Sep 2026 | 7,763 | 150,921 (0%) | 0% | 52.5 | 407,558 | Common Stock |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 48.89 per share. | 24 Aug 2026 | 9,370 | 87,319 (0%) | 0% | 48.9 | 458,099 | Common Stock |
| Ms. Karen N. Prange | Director | Sale of securities on an exchange or to another person at price $ 38.80 per share. | 05 Aug 2026 | 3,564 | 22,809 (0%) | 0% | 38.8 | 138,283 | Common Stock |
| Ms. Maggie Yuen | Director | Sale of securities on an exchange or to another person at price $ 38.42 per share. | 05 Aug 2026 | 3,500 | 14,015 (0%) | 0% | 38.4 | 134,470 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Jul 2026 | 4,000 | 774,434 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Jul 2026 | 700 | 778,434 (1%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 38.80 per share. | 29 Jul 2026 | 6,182 | 100,219 (0%) | 0% | 38.8 | 239,862 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 37.84 per share. | 28 Jul 2026 | 25,000 | 40,518 (0%) | 0% | 37.8 | 946,000 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 28 Jul 2026 | 25,000 | 65,518 (0%) | 0% | 20.0 | 498,750 | Common Stock |
| Mr. Sven A. Wehrwein | Director | 28 Jul 2026 | 25,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 38.88 per share. | 28 Jul 2026 | 6,000 | 86,511 (0%) | 0% | 38.9 | 233,280 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 23.78 per share. | 30 Jun 2026 | 636 | 779,134 (1%) | 0% | 23.8 | 15,124 | Common Stock |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 23.78 per share. | 30 Jun 2026 | 636 | 158,684 (0%) | 0% | 23.8 | 15,124 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 23.78 per share. | 30 Jun 2026 | 527 | 229,867 (0%) | 0% | 23.8 | 12,532 | Common Stock |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 23.78 per share. | 30 Jun 2026 | 636 | 96,689 (0%) | 0% | 23.8 | 15,124 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 23.78 per share. | 30 Jun 2026 | 636 | 92,511 (0%) | 0% | 23.8 | 15,124 | Common Stock |
| Ms. Karen N. Prange | Director | Sale of securities on an exchange or to another person at price $ 28.65 per share. | 20 May 2026 | 3,000 | 26,373 (0%) | 0% | 28.7 | 85,950 | Common Stock |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 55,954 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 40,518 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 29,373 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 128,318 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 39,859 (0%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 17,515 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 28,328 (0%) | 0% | 0 | Common Stock | |
| Mr. Shlomo Nachman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2026 | 6,144 | 24,655 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 28.13 per share. | 15 May 2026 | 5,000 | 91,875 (0%) | 0% | 28.1 | 140,650 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 29.83 per share. | 12 Mar 2026 | 5,000 | 96,875 (0%) | 0% | 29.8 | 149,150 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 29.83 per share. | 12 Mar 2026 | 5,000 | 96,875 (0%) | 0% | 29.8 | 149,150 | - |
| Mr. Robert S. White | Director | 10 Mar 2026 | 10,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.99 per share. | 10 Mar 2026 | 10,000 | 122,174 (0%) | 0% | 15.0 | 149,900 | Common Stock |
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.99 per share. | 10 Mar 2026 | 10,000 | 122,174 (0%) | 0% | 15.0 | 149,900 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Mar 2026 | 5,000 | 779,498 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Mar 2026 | 1,000 | 778,498 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Mar 2026 | 5,000 | 779,498 (1%) | 0% | 0 | - | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 06 Mar 2026 | 1,000 | 778,498 (1%) | 0% | 0 | - | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 68,618 | 755,995 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 72,777 | 784,498 (1%) | 0% | 31.3 | 2,275,009 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 101,280 | 857,275 (2%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 13,127 | 158,048 (0%) | 0% | 31.3 | 410,350 | Common Stock |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 30,390 | 155,977 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 171,175 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 42,386 | 226,756 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 22,948 | 229,340 (0%) | 0% | 31.3 | 717,354 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 25,532 | 252,288 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 15,586 | 106,401 (0%) | 0% | 31.3 | 487,218 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 121,987 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 27,991 | 106,789 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 22,965 | 204,893 (0%) | 0% | 31.3 | 717,886 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 39,987 | 204,757 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 23,101 | 227,858 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 27,991 | 96,542 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 111,740 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 15,687 | 96,053 (0%) | 0% | 31.3 | 490,376 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 30,390 | 102,262 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 117,460 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 15,585 | 101,875 (0%) | 0% | 31.3 | 487,187 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 42,386 | 226,756 (0%) | 0% | 0 | - | |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 25,532 | 252,288 (0%) | 0% | 0 | - | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 22,948 | 229,340 (0%) | 0% | 31.3 | 717,354 | - |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 27,991 | 106,789 (0%) | 0% | 0 | - | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 121,987 (0%) | 0% | 0 | - | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 15,586 | 106,401 (0%) | 0% | 31.3 | 487,218 | - |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 27,991 | 96,542 (0%) | 0% | 0 | - | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 111,740 (0%) | 0% | 0 | - | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 15,687 | 96,053 (0%) | 0% | 31.3 | 490,376 | - |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 39,987 | 204,757 (0%) | 0% | 0 | - | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 23,101 | 227,858 (0%) | 0% | 0 | - | |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 22,965 | 204,893 (0%) | 0% | 31.3 | 717,886 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 68,618 | 755,995 (1%) | 0% | 0 | - | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 101,280 | 857,275 (2%) | 0% | 0 | - | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 72,777 | 784,498 (1%) | 0% | 31.3 | 2,275,009 | - |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 30,390 | 102,262 (0%) | 0% | 0 | - | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 117,460 (0%) | 0% | 0 | - | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 15,585 | 101,875 (0%) | 0% | 31.3 | 487,187 | - |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 30,390 | 155,977 (0%) | 0% | 0 | - | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2026 | 15,198 | 171,175 (0%) | 0% | 0 | - | |
| Mr. Salvatore Privitera | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.26 per share. | 01 Mar 2026 | 13,127 | 158,048 (0%) | 0% | 31.3 | 410,350 | - |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 27.37 per share. | 31 Dec 2025 | 257 | 184,370 (0%) | 0% | 27.4 | 7,034 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 27.37 per share. | 31 Dec 2025 | 257 | 184,370 (0%) | 0% | 27.4 | 7,034 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Dec 2025 | 4,000 | 687,377 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Dec 2025 | 4,000 | 687,377 (1%) | 0% | 0 | - | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 37.29 per share. | 26 Nov 2025 | 5,166 | 78,798 (0%) | 0% | 37.3 | 192,640 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 37.29 per share. | 26 Nov 2025 | 5,166 | 78,798 (0%) | 0% | 37.3 | 192,640 | - |
| Mr. Sven A. Wehrwein | Director | 24 Nov 2025 | 4,967 | 25,000 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Sven A. Wehrwein | Director | 24 Nov 2025 | 5,033 | 29,967 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 38.00 per share. | 24 Nov 2025 | 4,967 | 34,374 (0%) | 0% | 38 | 188,746 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 37.32 per share. | 24 Nov 2025 | 5,033 | 34,374 (0%) | 0% | 37.3 | 187,832 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 24 Nov 2025 | 5,033 | 39,407 (0%) | 0% | 19.9 | 100,408 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 24 Nov 2025 | 4,967 | 39,341 (0%) | 0% | 20.0 | 99,092 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 24 Nov 2025 | 5,033 | 39,407 (0%) | 0% | 19.9 | 100,408 | - |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 37.32 per share. | 24 Nov 2025 | 5,033 | 34,374 (0%) | 0% | 37.3 | 187,832 | - |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 24 Nov 2025 | 4,967 | 39,341 (0%) | 0% | 20.0 | 99,092 | - |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 38.00 per share. | 24 Nov 2025 | 4,967 | 34,374 (0%) | 0% | 38 | 188,746 | - |
| Ms. Maggie Yuen | Director | Sale of securities on an exchange or to another person at price $ 35.72 per share. | 21 Nov 2025 | 3,000 | 11,371 (0%) | 0% | 35.7 | 107,160 | Common Stock |
| Ms. Maggie Yuen | Director | Sale of securities on an exchange or to another person at price $ 35.72 per share. | 21 Nov 2025 | 3,000 | 11,371 (0%) | 0% | 35.7 | 107,160 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 13 Nov 2025 | 6,000 | 691,377 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 13 Nov 2025 | 6,000 | 691,377 (1%) | 0% | 0 | - | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 36.30 per share. | 12 Sep 2025 | 3,000 | 83,964 (0%) | 0% | 36.3 | 108,900 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 36.30 per share. | 12 Sep 2025 | 3,000 | 83,964 (0%) | 0% | 36.3 | 108,900 | - |
| Mr. Sven A. Wehrwein | Director | 22 Aug 2025 | 5,000 | 35,000 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 37.00 per share. | 22 Aug 2025 | 5,000 | 34,374 (0%) | 0% | 37 | 185,000 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 22 Aug 2025 | 5,000 | 39,374 (0%) | 0% | 20.0 | 99,750 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 22 Aug 2025 | 5,000 | 39,374 (0%) | 0% | 20.0 | 99,750 | - |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 37.00 per share. | 22 Aug 2025 | 5,000 | 34,374 (0%) | 0% | 37 | 185,000 | - |
| Mr. Sven A. Wehrwein | Director | 19 Aug 2025 | 5,000 | 40,000 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 36.00 per share. | 19 Aug 2025 | 5,000 | 34,374 (0%) | 0% | 36 | 180,000 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 19 Aug 2025 | 5,000 | 39,374 (0%) | 0% | 20.0 | 99,750 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 19 Aug 2025 | 5,000 | 39,374 (0%) | 0% | 20.0 | 99,750 | - |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 36.00 per share. | 19 Aug 2025 | 5,000 | 34,374 (0%) | 0% | 36 | 180,000 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Aug 2025 | 10,000 | 697,377 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Aug 2025 | 10,000 | 697,377 (1%) | 0% | 0 | - | |
| Ms. Regina E. Groves | Director | Sale of securities on an exchange or to another person at price $ 36.82 per share. | 06 Aug 2025 | 2,452 | 33,715 (0%) | 0% | 36.8 | 90,283 | Common Stock |
| Ms. Regina Groves | Director | Sale of securities on an exchange or to another person at price $ 36.82 per share. | 06 Aug 2025 | 2,452 | 33,715 (0%) | 0% | 36.8 | 90,283 | - |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 36.58 per share. | 05 Aug 2025 | 2,500 | 71,872 (0%) | 0% | 36.6 | 91,450 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 36.58 per share. | 05 Aug 2025 | 2,500 | 71,872 (0%) | 0% | 36.6 | 91,450 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 707,377 (1%) | 0% | 25.8 | 21,240 | Common Stock |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 125,587 (0%) | 0% | 25.8 | 21,240 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 550 | 184,113 (0%) | 0% | 25.8 | 14,212 | Common Stock |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 68,551 (0%) | 0% | 25.8 | 21,240 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 74,372 (0%) | 0% | 25.8 | 21,240 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 707,377 (1%) | 0% | 25.8 | 21,240 | - |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 68,551 (0%) | 0% | 25.8 | 21,240 | - |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 550 | 184,113 (0%) | 0% | 25.8 | 14,212 | - |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 125,587 (0%) | 0% | 25.8 | 21,240 | - |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 25.84 per share. | 30 Jun 2025 | 822 | 74,372 (0%) | 0% | 25.8 | 21,240 | - |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 33.44 per share. | 28 May 2025 | 2,500 | 73,550 (0%) | 0% | 33.4 | 83,600 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 33.44 per share. | 28 May 2025 | 2,500 | 73,550 (0%) | 0% | 33.4 | 83,600 | - |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 49,810 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 34,374 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 23,229 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 112,174 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 36,167 (0%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 14,371 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 22,184 (0%) | 0% | 0 | Common Stock | |
| Mr. Shlomo Nachman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 18,511 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 23,229 (0%) | 0% | 0 | - | |
| Ms. Regina Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 36,167 (0%) | 0% | 0 | - | |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 49,810 (0%) | 0% | 0 | - | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 22,184 (0%) | 0% | 0 | - | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 34,374 (0%) | 0% | 0 | - | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 112,174 (0%) | 0% | 0 | - | |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 May 2025 | 5,401 | 14,371 (0%) | 0% | 0 | - | |
| Mr. Robert S. White | Director | 05 May 2025 | 10,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.62 per share. | 05 May 2025 | 10,000 | 106,773 (0%) | 0% | 22.6 | 226,200 | Common Stock |
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 22.62 per share. | 05 May 2025 | 10,000 | 106,773 (0%) | 0% | 22.6 | 226,200 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Mar 2025 | 4,000 | 706,555 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Mar 2025 | 4,000 | 706,555 (1%) | 0% | 0 | - | |
| Ms. Karen N. Prange | Director | Sale of securities on an exchange or to another person at price $ 38.12 per share. | 05 Mar 2025 | 6,100 | 17,828 (0%) | 0% | 38.1 | 232,532 | Common Stock |
| Ms. Karen N. Prange | Director | Sale of securities on an exchange or to another person at price $ 38.12 per share. | 05 Mar 2025 | 6,100 | 17,828 (0%) | 0% | 38.1 | 232,532 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 43,926 | 710,555 (1%) | 0% | 38.7 | 1,701,693 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 50,907 | 754,481 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 50,335 | 703,574 (1%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 22,586 | 126,583 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 133,162 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera, J.D. | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 8,397 | 124,765 (0%) | 0% | 38.7 | 325,300 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 32,266 | 186,493 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 15,050 | 183,563 (0%) | 0% | 38.7 | 583,037 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 12,120 | 198,613 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 9,673 | 86,964 (0%) | 0% | 38.7 | 374,732 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 96,637 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 19,359 | 90,058 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 30,330 | 169,400 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 9,003 | 178,403 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 13,633 | 164,770 (0%) | 0% | 38.7 | 528,142 | Common Stock |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 19,359 | 71,020 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 77,599 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist, J.D. | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 9,870 | 67,729 (0%) | 0% | 38.7 | 382,364 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 19,359 | 79,143 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 85,722 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 9,672 | 76,050 (0%) | 0% | 38.7 | 374,693 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 11,961 | 45,578 (0%) | 0% | 38.7 | 463,369 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 14,853 | 57,539 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 22,586 | 126,583 (0%) | 0% | 0 | - | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 133,162 (0%) | 0% | 0 | - | |
| Mr. Salvatore Privitera | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 8,397 | 124,765 (0%) | 0% | 38.7 | 325,300 | - |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 19,359 | 79,143 (0%) | 0% | 0 | - | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 85,722 (0%) | 0% | 0 | - | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 9,672 | 76,050 (0%) | 0% | 38.7 | 374,693 | - |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 19,359 | 71,020 (0%) | 0% | 0 | - | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 77,599 (0%) | 0% | 0 | - | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 9,870 | 67,729 (0%) | 0% | 38.7 | 382,364 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 50,335 | 703,574 (1%) | 0% | 0 | - | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 50,907 | 754,481 (1%) | 0% | 0 | - | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 43,926 | 710,555 (1%) | 0% | 38.7 | 1,701,693 | - |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 14,853 | 57,539 (0%) | 0% | 0 | - | |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 11,961 | 45,578 (0%) | 0% | 38.7 | 463,369 | - |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 32,266 | 186,493 (0%) | 0% | 0 | - | |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 12,120 | 198,613 (0%) | 0% | 0 | - | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 15,050 | 183,563 (0%) | 0% | 38.7 | 583,037 | - |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 19,359 | 90,058 (0%) | 0% | 0 | - | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 6,579 | 96,637 (0%) | 0% | 0 | - | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 9,673 | 86,964 (0%) | 0% | 38.7 | 374,732 | - |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 30,330 | 169,400 (0%) | 0% | 0 | - | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2025 | 9,003 | 178,403 (0%) | 0% | 0 | - | |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.74 per share. | 01 Mar 2025 | 13,633 | 164,770 (0%) | 0% | 38.7 | 528,142 | - |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 11 Dec 2024 | 585 | 70,699 (0%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Sale of securities on an exchange or to another person at price $ 24.07 per share. | 15 Aug 2024 | 3,500 | 8,970 (0%) | 0% | 24.1 | 84,245 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 14 Aug 2024 | 3,000 | 653,239 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 19.35 per share. | 28 Jun 2024 | 707 | 656,239 (1%) | 0% | 19.3 | 13,680 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 19.35 per share. | 28 Jun 2024 | 707 | 103,997 (0%) | 0% | 19.3 | 13,680 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 19.35 per share. | 28 Jun 2024 | 707 | 154,227 (0%) | 0% | 19.3 | 13,680 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 19.35 per share. | 28 Jun 2024 | 707 | 51,661 (0%) | 0% | 19.3 | 13,680 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 19.35 per share. | 28 Jun 2024 | 707 | 59,784 (0%) | 0% | 19.3 | 13,680 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 19.35 per share. | 28 Jun 2024 | 707 | 47,926 (0%) | 0% | 19.3 | 13,680 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Purchase of securities on an exchange or from another person at price $ 22.25 per share. | 30 May 2024 | 5,000 | 103,290 (0%) | 0% | 22.3 | 111,250 | Common Stock |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 44,409 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 28,973 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 23,928 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 96,773 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 30,766 (0%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 12,470 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 16,783 (0%) | 0% | 0 | Common Stock | |
| Mr. Shlomo Nachman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 May 2024 | 7,788 | 13,110 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 24.09 per share. | 01 May 2024 | 1,500 | 71,284 (0%) | 0% | 24.1 | 36,135 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 30.39 per share. | 01 Apr 2024 | 1,500 | 72,784 (0%) | 0% | 30.4 | 45,585 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 32.16 per share. | 18 Mar 2024 | 1,885 | 50,954 (0%) | 0% | 32.2 | 60,622 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 14 Mar 2024 | 2,000 | 655,532 (1%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 36.72 per share. | 12 Mar 2024 | 1,500 | 74,284 (0%) | 0% | 36.7 | 55,080 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 37.36 per share. | 05 Mar 2024 | 8,231 | 52,839 (0%) | 0% | 37.4 | 307,510 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 50,854 | 636,214 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 69,142 | 705,356 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.28 per share. | 01 Mar 2024 | 47,824 | 657,532 (1%) | 0% | 36.3 | 1,735,055 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 19,294 | 98,511 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.28 per share. | 01 Mar 2024 | 7,354 | 98,290 (0%) | 0% | 36.3 | 266,803 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 7,133 | 105,644 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 37,899 | 148,911 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.28 per share. | 01 Mar 2024 | 14,596 | 153,520 (0%) | 0% | 36.3 | 529,543 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 19,205 | 168,116 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 19,294 | 75,312 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 9,328 | 84,640 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.28 per share. | 01 Mar 2024 | 8,856 | 75,784 (0%) | 0% | 36.3 | 321,296 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | 01 Mar 2024 | 5,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Ms. Angela L. Wirick | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.95 per share. | 01 Mar 2024 | 5,000 | 139,070 (0%) | 0% | 17.0 | 84,750 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 16,461 | 134,070 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 31,008 | 117,609 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 8,231 | 61,070 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 22,050 | 52,839 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.28 per share. | 01 Mar 2024 | 8,855 | 59,077 (0%) | 0% | 36.3 | 321,259 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 19,294 | 58,604 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 9,328 | 67,932 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 01 Mar 2024 | 2,056 | 47,219 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2024 | 19,294 | 49,275 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | 23 Feb 2024 | 10,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.96 per share. | 23 Feb 2024 | 10,000 | 88,985 (0%) | 0% | 16.0 | 159,600 | Common Stock |
| Mr. Shlomo Nachman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Jan 2024 | 5,322 | 5,322 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 30.34 per share. | 29 Dec 2023 | 98 | 29,981 (0%) | 0% | 30.3 | 2,973 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Nov 2023 | 10,000 | 585,360 (1%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 34.43 per share. | 01 Nov 2023 | 1,248 | 30,789 (0%) | 0% | 34.4 | 42,969 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 57.23 per share. | 06 Aug 2023 | 5,191 | 86,601 (0%) | 0% | 57.2 | 297,081 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 04 Aug 2023 | 1,250 | 595,360 (1%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 57.09 per share. | 26 Jul 2023 | 3,417 | 32,037 (0%) | 0% | 57.1 | 195,077 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 557 | 596,610 (1%) | 0% | 38.1 | 21,227 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 557 | 79,217 (0%) | 0% | 38.1 | 21,227 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 557 | 111,012 (0%) | 0% | 38.1 | 21,227 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 547 | 56,018 (0%) | 0% | 38.1 | 20,846 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 557 | 35,454 (0%) | 0% | 38.1 | 21,227 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 557 | 39,310 (0%) | 0% | 38.1 | 21,227 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 38.11 per share. | 30 Jun 2023 | 450 | 29,883 (0%) | 0% | 38.1 | 17,150 | Common Stock |
| Ms. Karen N. Prange | Director | Sale of securities on an exchange or to another person at price $ 47.89 per share. | 08 Jun 2023 | 713 | 16,140 (0%) | 0% | 47.9 | 34,146 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 47.03 per share. | 06 Jun 2023 | 1,422 | 34,897 (0%) | 0% | 47.0 | 66,877 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 45.78 per share. | 01 Jun 2023 | 2,589 | 45,337 (0%) | 0% | 45.8 | 118,524 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.54 per share. | 01 Jun 2023 | 2,651 | 42,686 (0%) | 0% | 22.5 | 59,754 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 31 May 2023 | 1,000 | 596,053 (1%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Sale of securities on an exchange or to another person at price $ 47.04 per share. | 26 May 2023 | 4,313 | 4,682 (0%) | 0% | 47.0 | 202,884 | Common Stock |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 36,621 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 21,185 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 16,853 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 78,985 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 22,978 (0%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 8,995 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2023 | 3,186 | 8,995 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 44.83 per share. | 01 May 2023 | 4,417 | 36,319 (0%) | 0% | 44.8 | 198,014 | Common Stock |
| Mr. Mark A. Collar | Director | 13 Mar 2023 | 10,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Mark A. Collar | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.30 per share. | 13 Mar 2023 | 10,000 | 100,871 (0%) | 0% | 9.3 | 93,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Mar 2023 | 800 | 597,053 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 69,234 | 598,130 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Mar 2023 | 800 | 597,853 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 45,470 | 598,653 (1%) | 0% | 38.8 | 1,764,691 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 45,993 | 644,123 (1%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 8,036 | 68,870 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 16,104 | 84,974 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 6,314 | 78,660 (0%) | 0% | 38.8 | 245,046 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 27,054 | 122,142 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 11,687 | 110,455 (0%) | 0% | 38.8 | 453,572 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 15,453 | 95,088 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 8,036 | 46,450 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 16,104 | 62,554 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 7,083 | 55,471 (0%) | 0% | 38.8 | 274,891 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 3,532 | 91,792 (0%) | 0% | 38.8 | 137,077 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 24,478 | 95,324 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 6,894 | 40,736 (0%) | 0% | 38.8 | 267,556 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 8,036 | 31,526 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 16,104 | 47,630 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 16,104 | 43,546 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.81 per share. | 01 Mar 2023 | 4,793 | 38,753 (0%) | 0% | 38.8 | 186,016 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 8,036 | 27,442 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 12,239 | 29,433 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.48 per share. | 27 Feb 2023 | 20,000 | 75,799 (0%) | 0% | 8.5 | 169,600 | Common Stock |
| Mr. Robert S. White | Director | 27 Feb 2023 | 20,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 34.86 per share. | 30 Dec 2022 | 609 | 79,635 (0%) | 0% | 34.9 | 21,230 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 34.86 per share. | 30 Dec 2022 | 585 | 38,414 (0%) | 0% | 34.9 | 20,393 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 34.86 per share. | 30 Dec 2022 | 294 | 17,194 (0%) | 0% | 34.9 | 10,249 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 17 Nov 2022 | 6,000 | 528,896 (1%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 45.99 per share. | 15 Sep 2022 | 4,983 | 19,406 (0%) | 0% | 46.0 | 229,168 | Common Stock |
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.48 per share. | 31 Aug 2022 | 15,000 | 55,799 (0%) | 0% | 8.5 | 127,200 | Common Stock |
| Mr. Robert S. White | Director | 31 Aug 2022 | 15,000 | 20,000 | - | - | Non-qualified Stock Option (right to buy) | ||
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.94 per share. | 06 Aug 2022 | 5,191 | 70,846 (0%) | 0% | 50.9 | 264,430 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 34.73 per share. | 30 Jun 2022 | 350 | 534,896 (1%) | 0% | 34.7 | 12,156 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 34.73 per share. | 30 Jun 2022 | 350 | 60,834 (0%) | 0% | 34.7 | 12,156 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 34.73 per share. | 30 Jun 2022 | 350 | 23,490 (0%) | 0% | 34.7 | 12,156 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 34.73 per share. | 30 Jun 2022 | 350 | 24,389 (0%) | 0% | 34.7 | 12,156 | Common Stock |
| Ms. Deborah Lee Yount | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jun 2022 | 16,900 | 16,900 (0%) | 0% | 0 | Common Stock | |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 33,435 (0%) | 0% | 0 | Common Stock | |
| Mr. Mark A. Collar | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 90,871 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 17,999 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 13,667 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 40,799 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 19,792 (0%) | 0% | 0 | Common Stock | |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 5,809 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 May 2022 | 3,564 | 5,809 (0%) | 0% | 0 | Common Stock | |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 42.69 per share. | 13 May 2022 | 3,203 | 17,621 (0%) | 0% | 42.7 | 136,736 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 61.59 per share. | 08 Apr 2022 | 282 | 20,824 (0%) | 0% | 61.6 | 17,368 | Common Stock |
| Mr. Mark A. Collar | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.40 per share. | 16 Mar 2022 | 10,000 | 87,307 (0%) | 0% | 8.4 | 84,000 | Common Stock |
| Mr. Mark A. Collar | Director | 16 Mar 2022 | 10,000 | 0 | - | - | Non-qualified Stock Option (right to buy) | ||
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 67.66 per share. | 04 Mar 2022 | 1,409 | 21,106 (0%) | 0% | 67.7 | 95,333 | Common Stock |
| Mr. Robert S. White | Director | 03 Mar 2022 | 15,000 | 35,000 | - | - | Non-qualified Stock Option (right to buy) | ||
| Mr. Robert S. White | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.48 per share. | 03 Mar 2022 | 15,000 | 37,235 (0%) | 0% | 8.5 | 127,200 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 69.31 per share. | 02 Mar 2022 | 1,626 | 25,774 (0%) | 0% | 69.3 | 112,698 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 70.40 per share. | 02 Mar 2022 | 3,259 | 22,515 (0%) | 0% | 70.4 | 229,434 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 22,632 | 577,713 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 43,167 | 534,546 (1%) | 0% | 69.6 | 3,003,992 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 67,109 | 555,081 (1%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 6,700 | 60,484 (0%) | 0% | 69.6 | 466,253 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 6,825 | 67,184 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 7,789 | 60,359 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 12,573 | 90,466 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 11,440 | 79,026 (0%) | 0% | 69.6 | 796,110 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 13,182 | 77,893 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 7,789 | 38,478 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 7,474 | 37,829 (0%) | 0% | 69.6 | 520,116 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 6,825 | 45,303 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 3,449 | 76,037 (0%) | 0% | 69.6 | 240,016 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 9,340 | 79,486 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 6,825 | 30,439 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 7,789 | 23,614 (0%) | 0% | 0 | Common Stock | |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 7,299 | 23,140 (0%) | 0% | 69.6 | 507,937 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 6,825 | 31,513 (0%) | 0% | 0 | Common Stock | |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 7,474 | 24,039 (0%) | 0% | 69.6 | 520,116 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 7,789 | 24,688 (0%) | 0% | 0 | Common Stock | |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 6,466 | 32,797 (0%) | 0% | 0 | Common Stock | |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 69.59 per share. | 01 Mar 2022 | 5,397 | 27,400 (0%) | 0% | 69.6 | 375,577 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 5,991 | 26,331 (0%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Feb 2022 | 510 | 487,972 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Feb 2022 | 510 | 488,482 (1%) | 0% | 0 | Common Stock | |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 67.97 per share. | 11 Feb 2022 | 2,490 | 20,340 (0%) | 0% | 68.0 | 169,245 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 66.11 per share. | 14 Jan 2022 | 2,719 | 22,830 (0%) | 0% | 66.1 | 179,753 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 59.10 per share. | 31 Dec 2021 | 141 | 25,549 (0%) | 0% | 59.1 | 8,333 | - |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 59.10 per share. | 31 Dec 2021 | 141 | 488,992 (1%) | 0% | 59.1 | 8,333 | - |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 59.08 per share. | 31 Dec 2021 | 24 | 15,825 (0%) | 0% | 59.1 | 1,418 | - |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 59.08 per share. | 31 Dec 2021 | 24 | 16,899 (0%) | 0% | 59.1 | 1,418 | - |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 59.10 per share. | 31 Dec 2021 | 151 | 52,570 (0%) | 0% | 59.1 | 8,924 | - |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 70.88 per share. | 10 Dec 2021 | 1,528 | 25,408 (0%) | 0% | 70.9 | 108,305 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 07 Dec 2021 | 10,000 | 488,851 (1%) | 0% | 0 | Common Stock | |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 78.55 per share. | 12 Nov 2021 | 2,732 | 26,936 (0%) | 0% | 78.6 | 214,599 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Nov 2021 | 345 | 499,196 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Nov 2021 | 345 | 498,851 (1%) | 0% | 0 | Common Stock | |
| Mr. Mark A. Collar | Director | Sale of securities on an exchange or to another person at price $ 80.91 per share. | 04 Nov 2021 | 4,000 | 77,307 (0%) | 0% | 80.9 | 323,640 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 85.00 per share. | 04 Nov 2021 | 2,604 | 70,146 (0%) | 0% | 85 | 221,340 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 71.80 per share. | 08 Oct 2021 | 665 | 29,668 (0%) | 0% | 71.8 | 47,747 | Common Stock |
| Ms. Regina E. Groves | Director | Sale of securities on an exchange or to another person at price $ 74.73 per share. | 15 Sep 2021 | 3,156 | 16,194 (0%) | 0% | 74.7 | 235,848 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 75.54 per share. | 13 Sep 2021 | 21,444 | 64,711 (0%) | 0% | 75.5 | 1,619,880 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 77.18 per share. | 10 Sep 2021 | 1,227 | 30,333 (0%) | 0% | 77.2 | 94,700 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 73.10 per share. | 13 Aug 2021 | 3,232 | 31,560 (0%) | 0% | 73.1 | 236,259 | - |
| Mr. Douglas J. Seith | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 80.79 per share. | 09 Aug 2021 | 7,065 | 86,155 (0%) | 0% | 80.8 | 570,781 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 80.21 per share. | 06 Aug 2021 | 5,939 | 77,941 (0%) | 0% | 80.2 | 476,367 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 83.75 per share. | 06 Aug 2021 | 5,191 | 72,750 (0%) | 0% | 83.7 | 434,746 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 85.00 per share. | 30 Jul 2021 | 8,808 | 52,419 (0%) | 0% | 85 | 748,680 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 82.50 per share. | 28 Jul 2021 | 8,000 | 61,227 (0%) | 0% | 82.5 | 660,000 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 80.00 per share. | 20 Jul 2021 | 2,000 | 69,227 (0%) | 0% | 80 | 160,000 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 78.03 per share. | 16 Jul 2021 | 493 | 34,792 (0%) | 0% | 78.0 | 38,469 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 83.12 per share. | 12 Jul 2021 | 7,672 | 16,875 (0%) | 0% | 83.1 | 637,697 | Common Stock |
| Mr. Mark A. Collar | Director | Sale of securities on an exchange or to another person at price $ 79.61 per share. | 01 Jul 2021 | 3,000 | 81,307 (0%) | 0% | 79.6 | 238,830 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 45.72 per share. | 30 Jun 2021 | 251 | 499,541 (1%) | 0% | 45.7 | 11,476 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 45.72 per share. | 30 Jun 2021 | 171 | 71,227 (0%) | 0% | 45.7 | 7,818 | Common Stock |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 45.72 per share. | 30 Jun 2021 | 213 | 83,880 (0%) | 0% | 45.7 | 9,738 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 45.72 per share. | 30 Jun 2021 | 428 | 16,137 (0%) | 0% | 45.7 | 19,568 | Common Stock |
| Mr. Karl S. Dahlquist | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 79.53 per share. | 30 Jun 2021 | 336 | 15,801 (0%) | 0% | 79.5 | 26,722 | Common Stock |
| Dr. Vinayak Doraiswamy, PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 45.72 per share. | 30 Jun 2021 | 428 | 24,547 (0%) | 0% | 45.7 | 19,568 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Grant, award, or other acquisition of securities at price $ 45.72 per share. | 30 Jun 2021 | 193 | 35,285 (0%) | 0% | 45.7 | 8,824 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 80.00 per share. | 25 Jun 2021 | 4,119 | 30,689 (0%) | 0% | 80 | 329,520 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.30 per share. | 21 Jun 2021 | 15,000 | 55,808 (0%) | 0% | 18.3 | 274,500 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | 21 Jun 2021 | 15,000 | 0 | - | - | Stock Option (right to buy) | ||
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 76.36 per share. | 21 Jun 2021 | 6,000 | 34,808 (0%) | 0% | 76.4 | 458,160 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Sale of securities on an exchange or to another person at price $ 76.36 per share. | 21 Jun 2021 | 15,000 | 40,808 (0%) | 0% | 76.4 | 1,145,400 | Common Stock |
| Ms. Tonya A. Austin | Chief Human Resources Officer | Sale of securities on an exchange or to another person at price $ 76.36 per share. | 18 Jun 2021 | 2,620 | 35,092 (0%) | 0% | 76.4 | 200,063 | Common Stock |
| Ms. Maggie Yuen | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,245 | 2,245 (0%) | 0% | 0 | Common Stock | |
| Ms. Deborah H. Telman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2021 | 2,245 | 2,245 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | Sale of securities on an exchange or to another person at price $ 71.95 per share. | 26 May 2021 | 4,208 | 19,350 (0%) | 0% | 72.0 | 302,766 | Common Stock |
| Ms. B. Kristine Johnson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 29,871 (0%) | 0% | 0 | Common Stock | |
| Mr. Mark A. Collar | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 84,307 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 14,435 (0%) | 0% | 0 | Common Stock | |
| Ms. Karen N. Prange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 10,103 (0%) | 0% | 0 | Common Stock | |
| Mr. Robert S. White | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 22,235 (0%) | 0% | 0 | Common Stock | |
| Mr. Daniel P. Florin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 10,103 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 May 2021 | 1,749 | 23,558 (0%) | 0% | 0 | Common Stock | |
| Mr. Scott W. Drake | Director | Sale of securities on an exchange or to another person at price $ 76.52 per share. | 07 May 2021 | 4,631 | 41,036 (0%) | 0% | 76.5 | 354,364 | Common Stock |
| Mr. Scott W. Drake | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.98 per share. | 07 May 2021 | 38,641 | 79,677 (0%) | 0% | 9.0 | 346,996 | Common Stock |
| Mr. Scott W. Drake | Director | Sale of securities on an exchange or to another person at price $ 77.90 per share. | 07 May 2021 | 38,641 | 41,036 (0%) | 0% | 77.9 | 3,010,134 | Common Stock |
| Mr. Scott W. Drake | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 8.98 per share. | 07 May 2021 | 4,631 | 45,667 (0%) | 0% | 9.0 | 41,586 | Common Stock |
| Mr. Scott W. Drake | Director | 07 May 2021 | 38,641 | 11,359 | - | - | Stock Option (Right to Buy) | ||
| Mr. Scott W. Drake | Director | 07 May 2021 | 4,631 | 6,728 | - | - | Stock Option (Right to Buy) | ||
| Mr. Mark A. Collar | Director | 06 May 2021 | 10,000 | 0 | - | - | Stock Option (Right to Buy) | ||
| Mr. Mark A. Collar | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.17 per share. | 06 May 2021 | 10,000 | 82,558 (0%) | 0% | 14.2 | 141,700 | Common Stock |
| Mr. Mark Lanning | Director | 05 May 2021 | 10,000 | 0 | - | - | Stock Option (Right to Buy) | ||
| Mr. Mark Lanning | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.17 per share. | 05 May 2021 | 10,000 | 140,886 (0%) | 0% | 14.2 | 141,700 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 05 May 2021 | 2,300 | 40,808 (0%) | 0% | 0 | Common Stock | |
| Mr. Sven A. Wehrwein | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 19.95 per share. | 03 May 2021 | 5,000 | 17,686 (0%) | 0% | 20.0 | 99,750 | Common Stock |
| Mr. Sven A. Wehrwein | Director | 03 May 2021 | 5,000 | 45,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 78.19 per share. | 03 May 2021 | 5,000 | 12,686 (0%) | 0% | 78.2 | 390,950 | Common Stock |
| Mr. Sven A. Wehrwein | Director | Sale of securities on an exchange or to another person at price $ 77.75 per share. | 03 May 2021 | 5,000 | 12,686 (0%) | 0% | 77.8 | 388,750 | Common Stock |
| Ms. Regina E. Groves | Director | Purchase of securities on an exchange or from another person at price $ 76.68 per share. | 30 Apr 2021 | 34 | 16,228 (0%) | 0% | 76.7 | 2,607 | Common Stock |
| Mr. Mark A. Collar | Director | Sale of securities on an exchange or to another person at price $ 65.28 per share. | 01 Apr 2021 | 3,000 | 72,558 (0%) | 0% | 65.3 | 195,840 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 29,378 | 534,173 (1%) | 0% | 0 | Common Stock | |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.31 per share. | 01 Mar 2021 | 55,241 | 499,290 (1%) | 0% | 66.3 | 3,663,031 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 20,358 | 554,531 (1%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 6,528 | 74,974 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 4,901 | 79,875 (0%) | 0% | 0 | Common Stock | |
| Mr. Salvatore Privitera | Chief Technical Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.31 per share. | 01 Mar 2021 | 8,819 | 71,056 (0%) | 0% | 66.3 | 584,788 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.31 per share. | 01 Mar 2021 | 19,512 | 93,220 (0%) | 0% | 66.3 | 1,293,841 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 13,195 | 112,732 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 11,098 | 99,537 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.31 per share. | 01 Mar 2021 | 13,840 | 43,108 (0%) | 0% | 66.3 | 917,730 | Common Stock |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 6,409 | 56,948 (0%) | 0% | 0 | Common Stock | |
| Mr. Justin J. Noznesky | Chief Mktg & Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 7,931 | 50,539 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2021 | 3,770 | 90,002 (0%) | 0% | 0 | Common Stock | |
| Ms. Angela L. Wirick | Chief Financial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 66.31 per share. | 01 Mar 2021 | 6,335 | 83,667 (0%) | 0% | 66.3 | 420,074 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 63.00 per share. | 10 Feb 2021 | 25,000 | 504,795 (1%) | 0% | 63 | 1,575,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 10 Feb 2021 | 25,000 | 0 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 10 Feb 2021 | 25,000 | 25,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 10 Feb 2021 | 25,000 | 50,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 65.00 per share. | 10 Feb 2021 | 25,000 | 504,795 (1%) | 0% | 65 | 1,625,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 10 Feb 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 64.00 per share. | 10 Feb 2021 | 25,000 | 504,795 (1%) | 0% | 64 | 1,600,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 10 Feb 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 10 Feb 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 08 Feb 2021 | 25,000 | 75,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 08 Feb 2021 | 25,000 | 100,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 62.00 per share. | 08 Feb 2021 | 25,000 | 504,795 (1%) | 0% | 62 | 1,550,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 08 Feb 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 61.00 per share. | 08 Feb 2021 | 25,000 | 504,795 (1%) | 0% | 61 | 1,525,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 08 Feb 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 60.00 per share. | 02 Feb 2021 | 25,000 | 504,795 (1%) | 0% | 60 | 1,500,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 02 Feb 2021 | 25,000 | 125,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 02 Feb 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 60.00 per share. | 02 Feb 2021 | 14,941 | 95,939 (0%) | 0% | 60 | 896,460 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 11 Jan 2021 | 25,000 | 150,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 59.00 per share. | 11 Jan 2021 | 25,000 | 504,795 (1%) | 0% | 59 | 1,475,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 11 Jan 2021 | 25,000 | 529,795 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Mark A. Collar | Director | Sale of securities on an exchange or to another person at price $ 55.36 per share. | 04 Jan 2021 | 3,000 | 75,558 (0%) | 0% | 55.4 | 166,080 | Common Stock |
| Mr. Justin J. Noznesky | SVP, Mktg & Business Develop | Exercise or conversion of derivative security received from the company (such as an option) at price $ 18.30 per share. | 04 Jan 2021 | 15,000 | 66,005 (0%) | 0% | 18.3 | 274,500 | Common Stock |
| Mr. Justin J. Noznesky | SVP, Mktg & Business Develop | Sale of securities on an exchange or to another person at price $ 53.61 per share. | 04 Jan 2021 | 8,397 | 42,608 (0%) | 0% | 53.6 | 450,163 | Common Stock |
| Mr. Justin J. Noznesky | SVP, Mktg & Business Develop | 04 Jan 2021 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Justin J. Noznesky | SVP, Mktg & Business Develop | Sale of securities on an exchange or to another person at price $ 53.57 per share. | 04 Jan 2021 | 15,000 | 51,005 (0%) | 0% | 53.6 | 803,550 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 58.00 per share. | 23 Dec 2020 | 24,953 | 504,504 (1%) | 0% | 58 | 1,447,274 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 23 Dec 2020 | 24,953 | 529,457 (1%) | 0% | 21.0 | 525,011 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 58.00 per share. | 23 Dec 2020 | 47 | 504,504 (1%) | 0% | 58 | 2,726 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 23 Dec 2020 | 47 | 504,551 (1%) | 0% | 21.0 | 989 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 23 Dec 2020 | 24,953 | 175,000 | - | - | Stock Option (Right to buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 23 Dec 2020 | 47 | 199,953 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 56.00 per share. | 21 Dec 2020 | 25,000 | 504,504 (1%) | 0% | 56 | 1,400,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 21 Dec 2020 | 25,000 | 529,594 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 21 Dec 2020 | 24,751 | 529,255 (1%) | 0% | 21.0 | 520,761 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 55.00 per share. | 21 Dec 2020 | 24,751 | 504,504 (1%) | 0% | 55 | 1,361,305 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 21 Dec 2020 | 25,000 | 200,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 21 Dec 2020 | 25,000 | 0 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 21 Dec 2020 | 24,751 | 25,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 57.00 per share. | 21 Dec 2020 | 25,000 | 504,504 (1%) | 0% | 57 | 1,425,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 21 Dec 2020 | 25,000 | 529,504 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 17 Dec 2020 | 25,000 | 504,504 (1%) | 0% | 50 | 1,250,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 17 Dec 2020 | 50,249 | 49,751 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 17 Dec 2020 | 25,000 | 100,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 17 Dec 2020 | 25,000 | 0 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | 17 Dec 2020 | 25,000 | 0 | - | - | Stock Option (Right to buy) | ||
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 53.51 per share. | 17 Dec 2020 | 50,249 | 504,504 (1%) | 0% | 53.5 | 2,688,824 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 17 Dec 2020 | 50,249 | 554,753 (1%) | 0% | 21.0 | 1,057,239 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 52.00 per share. | 17 Dec 2020 | 25,000 | 504,504 (1%) | 0% | 52 | 1,300,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 21.04 per share. | 17 Dec 2020 | 25,000 | 529,504 (1%) | 0% | 21.0 | 526,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Sale of securities on an exchange or to another person at price $ 51.00 per share. | 17 Dec 2020 | 25,000 | 504,504 (1%) | 0% | 51 | 1,275,000 | Common Stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.91 per share. | 17 Dec 2020 | 25,000 | 529,504 (1%) | 0% | 5.9 | 147,750 | Common stock |
| Mr. Michael H. Carrel | Director, President, CEO, & Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.91 per share. | 17 Dec 2020 | 25,000 | 529,504 (1%) | 0% | 5.9 | 147,750 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 51.33 per share. | 17 Dec 2020 | 10,654 | 68,262 (0%) | 0% | 51.3 | 546,870 | Common Stock |
| Mr. Douglas J. Seith | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 50.00 per share. | 17 Dec 2020 | 18,617 | 110,880 (0%) | 0% | 50 | 930,850 | Common Stock |
| Mr. Salvatore Privitera | Chief Technical Officer | Sale of securities on an exchange or to another person at price $ 47.50 per share. | 09 Dec 2020 | 3,846 | 78,916 (0%) | 0% | 47.5 | 182,685 | Common Stock |
| Mr. Scott W. Drake | Director | Purchase of securities on an exchange or from another person at price $ 40.54 per share. | 17 Nov 2020 | 12,350 | 41,036 (0%) | 0% | 40.5 | 500,669 | Common Stock |
| Mr. Justin J. Noznesky | SVP, Mktg & Business Develop | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Nov 2020 | 250 | 51,005 (0%) | 0% | 0 | Common Stock | |
| Mr. Douglas J. Seith | Chief Operating Officer | Sale of securities on an exchange or to another person at price $ 40.09 per share. | 09 Oct 2020 | 29,161 | 129,497 (0%) | 0% | 40.1 | 1,169,064 | Common Stock |
| Mr. Mark A. Collar | Director | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 06 Oct 2020 | 2,330 | 78,558 (0%) | 0% | 40 | 93,200 | Common Stock |