XNAS 09 Oct, 2026 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.66 per share. | 02 Sep 2026 | 1,673 | 986,117 (5%) | 0% | 19.7 | 32,885 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 19.66 per share. | 02 Sep 2026 | 2,127 | 359,924 (1%) | 0% | 19.7 | 41,809 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.59 per share. | 01 Sep 2026 | 4,392 | 885,952 (4%) | 0% | 19.6 | 86,039 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.59 per share. | 01 Sep 2026 | 2,087 | 356,543 (1%) | 0% | 19.6 | 40,884 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.91 per share. | 27 Aug 2026 | 939 | 987,790 (5%) | 0% | 19.9 | 18,691 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 19.91 per share. | 27 Aug 2026 | 1,193 | 362,051 (1%) | 0% | 19.9 | 23,747 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.81 per share. | 26 Aug 2026 | 2,949 | 890,344 (4%) | 0% | 19.8 | 58,420 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.81 per share. | 26 Aug 2026 | 1,168 | 358,630 (1%) | 0% | 19.8 | 23,138 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.67 per share. | 26 Jul 2026 | 2,747 | 359,798 (1%) | 0% | 19.7 | 54,033 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.67 per share. | 26 Jul 2026 | 1,645 | 988,729 (5%) | 0% | 19.7 | 32,357 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.67 per share. | 26 Jul 2026 | 4,361 | 363,244 (1%) | 0% | 19.7 | 85,781 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.89 per share. | 02 Jun 2026 | 1,688 | 990,374 (5%) | 0% | 17.9 | 30,191 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 17.89 per share. | 02 Jun 2026 | 2,146 | 367,605 (1%) | 0% | 17.9 | 38,382 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.09 per share. | 01 Jun 2026 | 4,392 | 893,293 (4%) | 0% | 18.1 | 79,451 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.09 per share. | 01 Jun 2026 | 2,087 | 362,545 (1%) | 0% | 18.1 | 37,754 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 17.60 per share. | 27 May 2026 | 945 | 992,062 (5%) | 0% | 17.6 | 16,632 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 17.60 per share. | 27 May 2026 | 1,201 | 369,751 (1%) | 0% | 17.6 | 21,138 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.67 per share. | 26 May 2026 | 2,949 | 897,685 (4%) | 0% | 17.7 | 52,109 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.67 per share. | 26 May 2026 | 1,168 | 364,632 (1%) | 0% | 17.7 | 20,639 | Common Stock |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2026 | 11,117 | 28,099 (0%) | 0% | 0 | Common Stock | |
| Ms. Linda Marsh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2026 | 11,117 | 38,758 (0%) | 0% | 0 | Common Stock | |
| Dr. Michael Nohaile, PhD | Director | 14 May 2026 | 8,426 | 8,426 | - | - | Stock Option (Right to Buy) | ||
| Dr. Michael Nohaile, PhD | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2026 | 5,558 | 24,578 (0%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.31 per share. | 26 Apr 2026 | 2,747 | 365,800 (1%) | 0% | 16.3 | 44,804 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.31 per share. | 26 Apr 2026 | 1,645 | 993,007 (5%) | 0% | 16.3 | 26,830 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.31 per share. | 26 Apr 2026 | 4,361 | 370,952 (1%) | 0% | 16.3 | 71,128 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 09 Mar 2026 | 750,000 | 0 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 09 Mar 2026 | 750,000 | 0 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 2,949 | 918,200 (4%) | 0% | 24.8 | 73,017 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 17,566 | 900,634 (4%) | 0% | 15.3 | 269,287 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,133 | 376,894 (2%) | 0% | 15.3 | 17,369 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 1,168 | 378,027 (2%) | 0% | 24.8 | 28,920 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 8,347 | 368,547 (1%) | 0% | 15.3 | 127,960 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,018 | 1,001,062 (5%) | 0% | 15.3 | 15,606 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 897 | 1,002,080 (5%) | 0% | 24.8 | 22,210 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 6,410 | 994,652 (5%) | 0% | 15.3 | 98,265 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 8,147 | 375,313 (2%) | 0% | 15.3 | 124,894 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,079 | 383,460 (2%) | 0% | 15.3 | 16,541 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 1,140 | 384,539 (2%) | 0% | 24.8 | 28,226 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 6,410 | 994,652 (5%) | 0% | 15.3 | 98,265 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 6,410 | 994,652 (5%) | 0% | 15.3 | 98,265 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,018 | 1,001,062 (5%) | 0% | 15.3 | 15,606 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 897 | 1,002,080 (5%) | 0% | 24.8 | 22,210 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 8,347 | 368,547 (1%) | 0% | 15.3 | 127,960 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,133 | 376,894 (2%) | 0% | 15.3 | 17,369 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 1,168 | 378,027 (2%) | 0% | 24.8 | 28,920 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 17,566 | 900,634 (4%) | 0% | 15.3 | 269,287 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 2,949 | 918,200 (4%) | 0% | 24.8 | 73,017 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 8,147 | 375,313 (2%) | 0% | 15.3 | 124,894 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,079 | 383,460 (2%) | 0% | 15.3 | 16,541 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 1,140 | 384,539 (2%) | 0% | 24.8 | 28,226 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,018 | 1,001,062 (5%) | 0% | 15.3 | 15,606 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 897 | 1,002,080 (5%) | 0% | 24.8 | 22,210 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 8,347 | 368,547 (1%) | 0% | 15.3 | 127,960 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 1,140 | 384,539 (2%) | 0% | 24.8 | 28,226 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,079 | 383,460 (2%) | 0% | 15.3 | 16,541 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 8,147 | 375,313 (2%) | 0% | 15.3 | 124,894 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 2,949 | 918,200 (4%) | 0% | 24.8 | 73,017 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 17,566 | 900,634 (4%) | 0% | 15.3 | 269,287 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.76 per share. | 26 Feb 2026 | 1,168 | 378,027 (2%) | 0% | 24.8 | 28,920 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.33 per share. | 26 Feb 2026 | 1,133 | 376,894 (2%) | 0% | 15.3 | 17,369 | - |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 5,862 | 337,245 (1%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 31,962 | 385,679 (2%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 15,299 | 352,544 (1%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 27,341 | 379,885 (2%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 3,163 | 376,722 (2%) | 0% | 23.1 | 73,034 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,254 | 368,468 (1%) | 0% | 23.1 | 190,585 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 14,751 | 353,717 (1%) | 0% | 23.1 | 340,601 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 21,354 | 883,615 (4%) | 0% | 23.1 | 493,064 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 655 | 331,383 (1%) | 0% | 23.0 | 15,072 | - |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 31,182 | 379,195 (2%) | 0% | 0 | - | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 15,095 | 348,013 (1%) | 0% | 23.1 | 348,544 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,456 | 363,108 (1%) | 0% | 23.1 | 195,249 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 3,241 | 371,564 (1%) | 0% | 23.1 | 74,835 | - |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 26,673 | 374,805 (2%) | 0% | 0 | - | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 14,926 | 348,132 (1%) | 0% | 0 | - | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 5,721 | 333,206 (1%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 2,167 | 797,054 (4%) | 0% | 23.0 | 49,863 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 19,067 | 816,121 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 39,802 | 855,923 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 59,276 | 915,199 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 10,230 | 904,969 (4%) | 0% | 23.1 | 236,211 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 26,661 | 1,002,977 (5%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 31,760 | 851,855 (4%) | 0% | 23.1 | 733,338 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 69,294 | 921,149 (4%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 403 | 951,156 (5%) | 0% | 23.0 | 9,273 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 4,891 | 956,047 (5%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 31,962 | 385,679 (2%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 12,762 | 968,809 (5%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 22,806 | 991,615 (5%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 2,489 | 989,126 (5%) | 0% | 23.1 | 57,471 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 4,661 | 984,465 (5%) | 0% | 23.1 | 107,622 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,149 | 976,316 (5%) | 0% | 23.1 | 188,160 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 31,760 | 851,855 (4%) | 0% | 23.1 | 733,338 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 26,661 | 1,002,977 (5%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,149 | 976,316 (5%) | 0% | 23.1 | 188,160 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 4,661 | 984,465 (5%) | 0% | 23.1 | 107,622 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 2,489 | 989,126 (5%) | 0% | 23.1 | 57,471 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 22,806 | 991,615 (5%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 12,762 | 968,809 (5%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 4,891 | 956,047 (5%) | 0% | 0 | - | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 403 | 951,156 (5%) | 0% | 23.0 | 9,273 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 69,294 | 921,149 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 21,354 | 883,615 (4%) | 0% | 23.1 | 493,064 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 10,230 | 904,969 (4%) | 0% | 23.1 | 236,211 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 59,276 | 915,199 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 39,802 | 855,923 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 19,067 | 816,121 (4%) | 0% | 0 | - | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 2,167 | 797,054 (4%) | 0% | 23.0 | 49,863 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 14,751 | 353,717 (1%) | 0% | 23.1 | 340,601 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 661 | 327,485 (1%) | 0% | 23.0 | 15,210 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 2,167 | 797,054 (4%) | 0% | 23.0 | 49,863 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 69,294 | 921,149 (4%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 31,760 | 851,855 (4%) | 0% | 23.1 | 733,338 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 21,354 | 883,615 (4%) | 0% | 23.1 | 493,064 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 10,230 | 904,969 (4%) | 0% | 23.1 | 236,211 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 59,276 | 915,199 (4%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 39,802 | 855,923 (4%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 19,067 | 816,121 (4%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 661 | 327,485 (1%) | 0% | 23.0 | 15,210 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 5,721 | 333,206 (1%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 14,926 | 348,132 (1%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 26,673 | 374,805 (2%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 3,241 | 371,564 (1%) | 0% | 23.1 | 74,835 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,456 | 363,108 (1%) | 0% | 23.1 | 195,249 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 15,095 | 348,013 (1%) | 0% | 23.1 | 348,544 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 31,182 | 379,195 (2%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 26,661 | 1,002,977 (5%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 403 | 951,156 (5%) | 0% | 23.0 | 9,273 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 4,891 | 956,047 (5%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 12,762 | 968,809 (5%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 22,806 | 991,615 (5%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 2,489 | 989,126 (5%) | 0% | 23.1 | 57,471 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 4,661 | 984,465 (5%) | 0% | 23.1 | 107,622 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,149 | 976,316 (5%) | 0% | 23.1 | 188,160 | Common Stock |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 15,299 | 352,544 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 655 | 331,383 (1%) | 0% | 23.0 | 15,072 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,254 | 368,468 (1%) | 0% | 23.1 | 190,585 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 3,163 | 376,722 (2%) | 0% | 23.1 | 73,034 | Common Stock |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 27,341 | 379,885 (2%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 5,862 | 337,245 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 31,962 | 385,679 (2%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 14,751 | 353,717 (1%) | 0% | 23.1 | 340,601 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 661 | 327,485 (1%) | 0% | 23.0 | 15,210 | - |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 5,721 | 333,206 (1%) | 0% | 0 | - | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 14,926 | 348,132 (1%) | 0% | 0 | - | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 26,673 | 374,805 (2%) | 0% | 0 | - | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 3,241 | 371,564 (1%) | 0% | 23.1 | 74,835 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,456 | 363,108 (1%) | 0% | 23.1 | 195,249 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 15,095 | 348,013 (1%) | 0% | 23.1 | 348,544 | - |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 31,182 | 379,195 (2%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.01 per share. | 23 Feb 2026 | 655 | 331,383 (1%) | 0% | 23.0 | 15,072 | - |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 5,862 | 337,245 (1%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 15,299 | 352,544 (1%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2026 | 27,341 | 379,885 (2%) | 0% | 0 | - | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 3,163 | 376,722 (2%) | 0% | 23.1 | 73,034 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.09 per share. | 23 Feb 2026 | 8,254 | 368,468 (1%) | 0% | 23.1 | 190,585 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 3,004 | 328,146 (1%) | 0% | 27.5 | 82,700 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 1,331 | 951,559 (5%) | 0% | 27.5 | 36,642 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 4,711 | 332,038 (1%) | 0% | 27.5 | 129,694 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 1,331 | 951,559 (5%) | 0% | 27.5 | 36,642 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 4,711 | 332,038 (1%) | 0% | 27.5 | 129,694 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 3,004 | 328,146 (1%) | 0% | 27.5 | 82,700 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 3,004 | 328,146 (1%) | 0% | 27.5 | 82,700 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 4,711 | 332,038 (1%) | 0% | 27.5 | 129,694 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 27.53 per share. | 26 Jan 2026 | 1,331 | 951,559 (5%) | 0% | 27.5 | 36,642 | - |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 28.33 per share. | 02 Dec 2025 | 1,075 | 952,890 (5%) | 0% | 28.3 | 30,457 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 28.33 per share. | 02 Dec 2025 | 1,140 | 336,749 (1%) | 0% | 28.3 | 32,298 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 28.52 per share. | 01 Dec 2025 | 1,131 | 331,150 (1%) | 0% | 28.5 | 32,256 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 29.57 per share. | 28 Nov 2025 | 943 | 953,965 (5%) | 0% | 29.6 | 27,884 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 29.57 per share. | 28 Nov 2025 | 1,198 | 337,889 (1%) | 0% | 29.6 | 35,424 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.15 per share. | 26 Nov 2025 | 2,944 | 799,221 (4%) | 0% | 30.2 | 88,762 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.15 per share. | 26 Nov 2025 | 1,166 | 332,281 (1%) | 0% | 30.2 | 35,155 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 30.47 per share. | 24 Nov 2025 | 535 | 954,908 (5%) | 0% | 30.5 | 16,303 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 30.47 per share. | 24 Nov 2025 | 681 | 339,087 (1%) | 0% | 30.5 | 20,752 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.00 per share. | 23 Nov 2025 | 2,116 | 802,165 (4%) | 0% | 30 | 63,480 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 30.00 per share. | 23 Nov 2025 | 671 | 333,447 (1%) | 0% | 30 | 20,130 | Common Stock |
| Mr. Jian Xie | President and COO | Gift of securities by or to the insider at price $ 0.00 per share. | 19 Nov 2025 | 10,000 | 339,768 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 29.10 per share. | 19 Nov 2025 | 10,000 | 349,768 (1%) | 0% | 29.1 | 290,983 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.74 per share. | 26 Oct 2025 | 2,743 | 334,118 (1%) | 0% | 23.7 | 65,119 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.74 per share. | 26 Oct 2025 | 1,642 | 955,443 (5%) | 0% | 23.7 | 38,981 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.74 per share. | 26 Oct 2025 | 4,353 | 359,768 (1%) | 0% | 23.7 | 103,340 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 22.03 per share. | 03 Sep 2025 | 1,063 | 957,085 (5%) | 0% | 22.0 | 23,414 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 22.03 per share. | 03 Sep 2025 | 1,128 | 364,121 (1%) | 0% | 22.0 | 24,846 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 22.17 per share. | 01 Sep 2025 | 1,131 | 336,861 (1%) | 0% | 22.2 | 25,074 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 21.48 per share. | 27 Aug 2025 | 943 | 958,148 (5%) | 0% | 21.5 | 20,260 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 21.48 per share. | 27 Aug 2025 | 1,199 | 365,249 (1%) | 0% | 21.5 | 25,760 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.47 per share. | 26 Aug 2025 | 2,944 | 804,281 (4%) | 0% | 21.5 | 63,208 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.47 per share. | 26 Aug 2025 | 1,166 | 337,992 (1%) | 0% | 21.5 | 25,034 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 21.50 per share. | 25 Aug 2025 | 548 | 959,091 (5%) | 0% | 21.5 | 11,783 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 21.50 per share. | 25 Aug 2025 | 696 | 366,448 (1%) | 0% | 21.5 | 14,965 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.77 per share. | 23 Aug 2025 | 2,115 | 807,225 (4%) | 0% | 21.8 | 46,044 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.77 per share. | 23 Aug 2025 | 670 | 339,158 (1%) | 0% | 21.8 | 14,586 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.53 per share. | 01 Aug 2025 | 1,339 | 809,340 (4%) | 0% | 18.5 | 24,812 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.37 per share. | 26 Jul 2025 | 2,743 | 339,828 (1%) | 0% | 18.4 | 50,389 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.37 per share. | 26 Jul 2025 | 1,642 | 959,639 (5%) | 0% | 18.4 | 30,164 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.37 per share. | 26 Jul 2025 | 4,352 | 367,144 (1%) | 0% | 18.4 | 79,946 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 09 Jun 2025 | 800,000 | 0 | - | - | Forward sale contract (obligation to sell) | ||
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.29 per share. | 02 Jun 2025 | 754 | 961,281 (5%) | 0% | 20.3 | 15,299 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 20.29 per share. | 02 Jun 2025 | 1,135 | 371,496 (1%) | 0% | 20.3 | 23,030 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.72 per share. | 01 Jun 2025 | 1,131 | 342,571 (1%) | 0% | 20.7 | 23,434 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.57 per share. | 27 May 2025 | 383 | 962,691 (5%) | 0% | 20.6 | 7,880 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.52 per share. | 27 May 2025 | 656 | 962,035 (5%) | 0% | 20.5 | 13,459 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 20.52 per share. | 27 May 2025 | 1,183 | 372,631 (1%) | 0% | 20.5 | 24,271 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 20.58 per share. | 27 May 2025 | 690 | 373,814 (1%) | 0% | 20.6 | 14,197 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.31 per share. | 23 May 2025 | 2,944 | 810,679 (4%) | 0% | 20.3 | 59,793 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.31 per share. | 23 May 2025 | 2,116 | 813,623 (4%) | 0% | 20.3 | 42,976 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.31 per share. | 23 May 2025 | 1,166 | 343,702 (1%) | 0% | 20.3 | 23,681 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.31 per share. | 23 May 2025 | 671 | 344,868 (1%) | 0% | 20.3 | 13,628 | Common Stock |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2025 | 8,982 | 16,982 (0%) | 0% | 0 | Common Stock | |
| Ms. Linda Marsh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2025 | 8,982 | 27,641 (0%) | 0% | 0 | Common Stock | |
| Dr. Michael Nohaile, PhD | Director | 15 May 2025 | 6,311 | 6,311 | - | - | Stock Option (Right to Buy) | ||
| Dr. Michael Nohaile, PhD | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 May 2025 | 4,491 | 19,020 (0%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.25 per share. | 01 May 2025 | 1,339 | 815,739 (4%) | 0% | 17.3 | 23,098 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.35 per share. | 30 Apr 2025 | 79 | 963,074 (5%) | 0% | 17.4 | 1,371 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.88 per share. | 26 Apr 2025 | 2,743 | 345,539 (1%) | 0% | 18.9 | 51,788 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.88 per share. | 26 Apr 2025 | 1,157 | 963,153 (5%) | 0% | 18.9 | 21,844 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.88 per share. | 26 Apr 2025 | 4,353 | 374,504 (2%) | 0% | 18.9 | 82,185 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 15.96 per share. | 05 Mar 2025 | 100,000 | 348,282 (1%) | 0% | 16.0 | 1,596,470 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.45 per share. | 01 Mar 2025 | 1,556 | 248,282 (1%) | 0% | 15.4 | 24,040 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.45 per share. | 01 Mar 2025 | 985 | 964,310 (5%) | 0% | 15.4 | 15,218 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 15.45 per share. | 01 Mar 2025 | 1,481 | 378,857 (2%) | 0% | 15.4 | 22,881 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 3,384 | 204,172 (1%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.24 per share. | 25 Feb 2025 | 4,662 | 249,838 (1%) | 0% | 16.2 | 75,711 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 44,199 | 254,500 (1%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 8,228 | 210,301 (1%) | 0% | 16.3 | 134,034 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 3,024 | 218,529 (1%) | 0% | 16.3 | 49,261 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 1,914 | 221,553 (1%) | 0% | 16.3 | 31,179 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 13,949 | 223,467 (1%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 5,346 | 209,518 (1%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 4,571 | 925,588 (4%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.24 per share. | 25 Feb 2025 | 2,523 | 965,295 (5%) | 0% | 16.2 | 40,974 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 37,790 | 967,818 (5%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 4,639 | 930,028 (4%) | 0% | 16.3 | 75,569 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 1,636 | 934,667 (4%) | 0% | 16.3 | 26,650 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 1,211 | 936,303 (5%) | 0% | 16.3 | 19,727 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 3,384 | 921,017 (4%) | 0% | 0 | Common Stock | |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 11,926 | 937,514 (5%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 3,384 | 332,613 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 5,480 | 338,093 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 14,297 | 352,390 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 1,823 | 350,567 (1%) | 0% | 16.3 | 29,697 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 2,951 | 347,616 (1%) | 0% | 16.3 | 48,072 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 8,031 | 339,585 (1%) | 0% | 16.3 | 130,825 | Common Stock |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 45,304 | 384,889 (2%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.24 per share. | 25 Feb 2025 | 4,551 | 380,338 (2%) | 0% | 16.2 | 73,908 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 8,031 | 339,585 (1%) | 0% | 16.3 | 130,825 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.24 per share. | 25 Feb 2025 | 4,551 | 380,338 (2%) | 0% | 16.2 | 73,908 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2025 | 2,951 | 347,616 (1%) | 0% | 16.3 | 48,072 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.46 per share. | 23 Feb 2025 | 2,324 | 699,915 (3%) | 0% | 16.5 | 38,253 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.46 per share. | 23 Feb 2025 | 733 | 200,788 (1%) | 0% | 16.5 | 12,065 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.46 per share. | 23 Feb 2025 | 417 | 917,633 (4%) | 0% | 16.5 | 6,864 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.46 per share. | 23 Feb 2025 | 719 | 329,229 (1%) | 0% | 16.5 | 11,835 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.00 per share. | 30 Jan 2025 | 90 | 918,050 (4%) | 0% | 17 | 1,530 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.21 per share. | 26 Jan 2025 | 3,000 | 201,521 (1%) | 0% | 17.2 | 51,630 | Common Stock |
| Dr. Hanlin Gao, M.D.,PhD | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.21 per share. | 26 Jan 2025 | 1,329 | 918,140 (4%) | 0% | 17.2 | 22,872 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.21 per share. | 26 Jan 2025 | 4,733 | 329,948 (1%) | 0% | 17.2 | 81,455 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 19.50 per share. | 03 Dec 2024 | 1,455 | 334,681 (1%) | 0% | 19.5 | 28,372 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 19.50 per share. | 03 Dec 2024 | 1,373 | 919,469 (4%) | 0% | 19.5 | 26,773 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 18.30 per share. | 01 Dec 2024 | 1,553 | 204,521 (1%) | 0% | 18.3 | 28,420 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 17.87 per share. | 25 Nov 2024 | 669 | 206,074 (1%) | 0% | 17.9 | 11,955 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 18.26 per share. | 25 Nov 2024 | 497 | 920,842 (4%) | 0% | 18.3 | 9,075 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 18.26 per share. | 25 Nov 2024 | 2,227 | 703,711 (3%) | 0% | 18.3 | 40,663 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 18.26 per share. | 25 Nov 2024 | 689 | 336,136 (1%) | 0% | 18.3 | 12,581 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.61 per share. | 01 Nov 2024 | 1,337 | 705,938 (3%) | 0% | 21.6 | 28,893 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.27 per share. | 30 Oct 2024 | 79 | 921,339 (4%) | 0% | 20.3 | 1,601 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.42 per share. | 26 Oct 2024 | 2,738 | 206,743 (1%) | 0% | 19.4 | 53,172 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.42 per share. | 26 Oct 2024 | 1,639 | 921,418 (4%) | 0% | 19.4 | 31,829 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 19.42 per share. | 26 Oct 2024 | 4,345 | 336,825 (1%) | 0% | 19.4 | 84,380 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 21.96 per share. | 03 Sep 2024 | 1,674 | 209,481 (1%) | 0% | 22.0 | 36,763 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 21.96 per share. | 03 Sep 2024 | 1,503 | 923,057 (4%) | 0% | 22.0 | 33,007 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 21.96 per share. | 03 Sep 2024 | 1,594 | 341,170 (1%) | 0% | 22.0 | 35,006 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 22.83 per share. | 27 Aug 2024 | 2,313 | 707,275 (3%) | 0% | 22.8 | 52,813 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 22.83 per share. | 27 Aug 2024 | 733 | 211,155 (1%) | 0% | 22.8 | 16,737 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 22.83 per share. | 27 Aug 2024 | 563 | 924,560 (4%) | 0% | 22.8 | 12,855 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 22.83 per share. | 27 Aug 2024 | 715 | 342,764 (1%) | 0% | 22.8 | 16,326 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.06 per share. | 03 Aug 2024 | 1,412 | 211,888 (1%) | 0% | 25.1 | 35,385 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.06 per share. | 03 Aug 2024 | 6,719 | 343,479 (1%) | 0% | 25.1 | 168,378 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.57 per share. | 01 Aug 2024 | 1,337 | 709,588 (3%) | 0% | 23.6 | 31,513 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.95 per share. | 30 Jul 2024 | 111 | 925,123 (4%) | 0% | 23.9 | 2,658 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.66 per share. | 26 Jul 2024 | 2,738 | 213,300 (1%) | 0% | 23.7 | 64,781 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.66 per share. | 26 Jul 2024 | 1,154 | 925,234 (4%) | 0% | 23.7 | 27,304 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.66 per share. | 26 Jul 2024 | 4,345 | 350,198 (1%) | 0% | 23.7 | 102,803 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.65 per share. | 01 Jun 2024 | 424 | 216,038 (1%) | 0% | 20.7 | 8,756 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.65 per share. | 01 Jun 2024 | 1,129 | 216,462 (1%) | 0% | 20.7 | 23,314 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.65 per share. | 01 Jun 2024 | 268 | 926,388 (4%) | 0% | 20.6 | 5,534 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.65 per share. | 01 Jun 2024 | 714 | 926,656 (4%) | 0% | 20.6 | 14,744 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.65 per share. | 01 Jun 2024 | 1,075 | 354,947 (1%) | 0% | 20.7 | 22,199 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.65 per share. | 01 Jun 2024 | 404 | 354,543 (1%) | 0% | 20.7 | 8,343 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.14 per share. | 23 May 2024 | 2,111 | 710,925 (3%) | 0% | 21.1 | 44,627 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.14 per share. | 23 May 2024 | 669 | 217,591 (1%) | 0% | 21.1 | 14,143 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.14 per share. | 23 May 2024 | 362 | 927,370 (4%) | 0% | 21.1 | 7,653 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.14 per share. | 23 May 2024 | 653 | 356,022 (1%) | 0% | 21.1 | 13,804 | Common Stock |
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 4,000 | 8,000 (0%) | 0% | 0 | Common Stock | |
| Ms. Regina E. Groves | Director | 16 May 2024 | 5,481 | 5,481 | - | - | Stock Option (Right to Buy) | ||
| Ms. Linda Marsh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 8,000 | 18,659 (0%) | 0% | 0 | Common Stock | |
| Mr. Michael Nohaile, PhD | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 May 2024 | 8,000 | 14,529 (0%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.50 per share. | 03 May 2024 | 1,412 | 218,260 (1%) | 0% | 21.5 | 30,358 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 21.50 per share. | 03 May 2024 | 6,719 | 356,675 (1%) | 0% | 21.5 | 144,459 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.70 per share. | 01 May 2024 | 1,337 | 713,036 (3%) | 0% | 20.7 | 27,676 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.35 per share. | 30 Apr 2024 | 79 | 927,732 (4%) | 0% | 20.4 | 1,608 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.10 per share. | 26 Apr 2024 | 2,738 | 219,672 (1%) | 0% | 20.1 | 55,034 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.10 per share. | 26 Apr 2024 | 4,344 | 363,394 (1%) | 0% | 20.1 | 87,314 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 20.10 per share. | 26 Apr 2024 | 1,154 | 927,811 (4%) | 0% | 20.1 | 23,195 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 08 Mar 2024 | 1,000,000 | 0 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 08 Mar 2024 | 1,000,000 | 1,000,000 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.24 per share. | 01 Mar 2024 | 1,129 | 222,834 (1%) | 0% | 23.2 | 26,238 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.24 per share. | 01 Mar 2024 | 424 | 222,410 (1%) | 0% | 23.2 | 9,854 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.24 per share. | 01 Mar 2024 | 268 | 928,965 (4%) | 0% | 23.2 | 6,228 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.24 per share. | 01 Mar 2024 | 704 | 929,233 (4%) | 0% | 23.2 | 16,361 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.24 per share. | 01 Mar 2024 | 404 | 367,738 (1%) | 0% | 23.2 | 9,389 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.24 per share. | 01 Mar 2024 | 1,075 | 368,142 (1%) | 0% | 23.2 | 24,983 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 2,111 | 347,285 (1%) | 0% | 24.3 | 51,213 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 24,732 | 223,963 (1%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 6,997 | 659,474 (3%) | 0% | 24.3 | 169,747 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 1,402 | 910,679 (4%) | 0% | 24.3 | 34,013 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 65,952 | 714,373 (3%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 6,359 | 349,396 (1%) | 0% | 0 | Common Stock | |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 5,304 | 912,081 (4%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 25,350 | 369,217 (1%) | 0% | 0 | Common Stock | |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 3,927 | 906,777 (4%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 20,679 | 666,471 (3%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 3,418 | 343,867 (1%) | 0% | 24.3 | 82,921 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 11,053 | 648,421 (3%) | 0% | 24.3 | 268,146 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 2,217 | 202,733 (1%) | 0% | 24.3 | 53,784 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 21,146 | 929,937 (4%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 3,502 | 199,231 (1%) | 0% | 24.3 | 84,959 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 13,090 | 645,792 (3%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 6,203 | 204,950 (1%) | 0% | 0 | Common Stock | |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.26 per share. | 26 Feb 2024 | 1,888 | 908,791 (4%) | 0% | 24.3 | 45,803 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 3,927 | 198,747 (1%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2024 | 3,927 | 343,037 (1%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2024 | 11,280 | 711,195 (3%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2024 | 17,820 | 729,015 (3%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2024 | 37,197 | 766,212 (4%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2024 | 6,041 | 760,171 (4%) | 0% | 16.3 | 98,408 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2024 | 9,543 | 750,628 (4%) | 0% | 16.3 | 155,455 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.29 per share. | 25 Feb 2024 | 19,997 | 730,631 (3%) | 0% | 16.3 | 325,751 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2024 | 98,220 | 828,851 (4%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.24 per share. | 25 Feb 2024 | 11,773 | 817,078 (4%) | 0% | 16.2 | 191,194 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 23 Feb 2024 | 8,667 | 632,702 (3%) | 0% | 24.1 | 208,528 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 23 Feb 2024 | 2,612 | 339,110 (1%) | 0% | 24.1 | 62,845 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 23 Feb 2024 | 1,617 | 902,850 (4%) | 0% | 24.1 | 38,905 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.06 per share. | 23 Feb 2024 | 2,670 | 194,820 (1%) | 0% | 24.1 | 64,240 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.65 per share. | 03 Feb 2024 | 982 | 197,490 (1%) | 0% | 24.6 | 24,206 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.65 per share. | 03 Feb 2024 | 6,719 | 351,722 (1%) | 0% | 24.6 | 165,623 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.99 per share. | 01 Feb 2024 | 1,094 | 641,369 (3%) | 0% | 25.0 | 27,339 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 16.64 per share. | 01 Feb 2024 | 1,472 | 702,239 (3%) | 0% | 16.6 | 24,494 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.00 per share. | 30 Jan 2024 | 90 | 904,467 (4%) | 0% | 25 | 2,250 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.60 per share. | 26 Jan 2024 | 4,683 | 358,441 (1%) | 0% | 25.6 | 119,885 | Common Stock |
| Mr. Hanlin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.60 per share. | 26 Jan 2024 | 1,325 | 904,557 (4%) | 0% | 25.6 | 33,920 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 25.60 per share. | 26 Jan 2024 | 1,988 | 198,472 (1%) | 0% | 25.6 | 50,893 | Common Stock |
| Mr. Jian Xie | President and COO | 31 Dec 2023 | 4,300 | 358,824 (1%) | 0% | 108.2 | 465,327 | Common Stock | |
| Mr. Jian Xie | President and COO | 31 Dec 2023 | 5,700 | 353,124 (1%) | 0% | 101.7 | 579,480 | Common Stock | |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 26.32 per share. | 11 Dec 2023 | 10,000 | 375,124 (2%) | 0% | 26.3 | 263,179 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 26.69 per share. | 11 Dec 2023 | 12,000 | 363,124 (1%) | 0% | 26.7 | 320,274 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 27.57 per share. | 04 Dec 2023 | 1,437 | 200,460 (1%) | 0% | 27.6 | 39,623 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 27.57 per share. | 04 Dec 2023 | 1,779 | 385,124 (2%) | 0% | 27.6 | 49,053 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 27.57 per share. | 04 Dec 2023 | 1,437 | 905,882 (4%) | 0% | 27.6 | 39,623 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 27.25 per share. | 16 Nov 2023 | 1,307 | 201,897 (1%) | 0% | 27.3 | 35,617 | - |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 27.25 per share. | 16 Nov 2023 | 1,617 | 386,903 (2%) | 0% | 27.3 | 44,065 | - |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 27.25 per share. | 16 Nov 2023 | 1,617 | 386,903 (2%) | 0% | 27.3 | 44,065 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 27.25 per share. | 16 Nov 2023 | 1,307 | 201,897 (1%) | 0% | 27.3 | 35,617 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.94 per share. | 03 Nov 2023 | 7,669 | 388,520 (2%) | 0% | 26.9 | 206,603 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.94 per share. | 03 Nov 2023 | 1,240 | 203,204 (1%) | 0% | 26.9 | 33,406 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.94 per share. | 03 Nov 2023 | 1,240 | 203,204 (1%) | 0% | 26.9 | 33,406 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 26.94 per share. | 03 Nov 2023 | 7,669 | 388,520 (2%) | 0% | 26.9 | 206,603 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.75 per share. | 01 Nov 2023 | 1,309 | 642,463 (3%) | 0% | 23.8 | 31,089 | - |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.75 per share. | 01 Nov 2023 | 1,309 | 642,463 (3%) | 0% | 23.8 | 31,089 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.64 per share. | 30 Oct 2023 | 109 | 907,319 (4%) | 0% | 23.6 | 2,577 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 23.64 per share. | 30 Oct 2023 | 109 | 907,319 (4%) | 0% | 23.6 | 2,577 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.03 per share. | 26 Oct 2023 | 5,504 | 907,428 (4%) | 0% | 24.0 | 132,234 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.02 per share. | 26 Oct 2023 | 9,617 | 204,444 (1%) | 0% | 24.0 | 231,048 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.03 per share. | 26 Oct 2023 | 19,833 | 396,189 (2%) | 0% | 24.0 | 476,488 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.03 per share. | 26 Oct 2023 | 19,833 | 396,189 (2%) | 0% | 24.0 | 476,488 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.02 per share. | 26 Oct 2023 | 9,617 | 204,444 (1%) | 0% | 24.0 | 231,048 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 24.03 per share. | 26 Oct 2023 | 5,504 | 907,428 (4%) | 0% | 24.0 | 132,234 | - |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 31.41 per share. | 07 Sep 2023 | 1,492 | 416,022 (2%) | 0% | 31.4 | 46,861 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 31.41 per share. | 07 Sep 2023 | 1,492 | 214,061 (1%) | 0% | 31.4 | 46,861 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 31.41 per share. | 07 Sep 2023 | 1,041 | 912,932 (4%) | 0% | 31.4 | 32,696 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 31.41 per share. | 07 Sep 2023 | 1,041 | 912,932 (4%) | 0% | 31.4 | 32,696 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 31.41 per share. | 07 Sep 2023 | 1,492 | 214,061 (1%) | 0% | 31.4 | 46,861 | - |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 31.41 per share. | 07 Sep 2023 | 1,492 | 416,022 (2%) | 0% | 31.4 | 46,861 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 33.62 per share. | 28 Aug 2023 | 10,299 | 215,553 (1%) | 0% | 33.6 | 346,297 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 21 Aug 2023 | 750,000 | 750,000 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 21 Aug 2023 | 750,000 | 0 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 33.88 per share. | 17 Aug 2023 | 491 | 227,159 (1%) | 0% | 33.9 | 16,636 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 33.88 per share. | 17 Aug 2023 | 1,307 | 225,852 (1%) | 0% | 33.9 | 44,283 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 33.88 per share. | 17 Aug 2023 | 342 | 913,973 (4%) | 0% | 33.9 | 11,587 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 33.88 per share. | 17 Aug 2023 | 1,307 | 417,514 (2%) | 0% | 33.9 | 44,283 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 40.08 per share. | 03 Aug 2023 | 1,240 | 227,650 (1%) | 0% | 40.1 | 49,699 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 40.08 per share. | 03 Aug 2023 | 6,198 | 418,821 (2%) | 0% | 40.1 | 248,416 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.83 per share. | 01 Aug 2023 | 4,783 | 643,772 (3%) | 0% | 38.8 | 185,724 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.83 per share. | 01 Aug 2023 | 775 | 425,019 (2%) | 0% | 38.8 | 30,093 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 38.63 per share. | 30 Jul 2023 | 76 | 914,315 (4%) | 0% | 38.6 | 2,936 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 40.30 per share. | 02 Jun 2023 | 1,403 | 228,890 (1%) | 0% | 40.3 | 56,535 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 40.30 per share. | 02 Jun 2023 | 1,000 | 914,391 (4%) | 0% | 40.3 | 40,296 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 40.30 per share. | 02 Jun 2023 | 1,433 | 425,794 (2%) | 0% | 40.3 | 57,744 | Common Stock |
| Ms. Regina E. Groves | Director | 18 May 2023 | 6,759 | 6,759 | - | - | Stock Option (Right to Buy) | ||
| Ms. Linda Marsh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 5,059 | 10,659 (0%) | 0% | 0 | Common Stock | |
| Mr. Michael Nohaile | Director | 18 May 2023 | 3,380 | 3,380 | - | - | Stock Option (Right to Buy) | ||
| Mr. Michael Nohaile | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 2,529 | 6,529 (0%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 35.46 per share. | 17 May 2023 | 921 | 230,638 (1%) | 0% | 35.5 | 32,661 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 35.46 per share. | 17 May 2023 | 345 | 230,293 (1%) | 0% | 35.5 | 12,234 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 35.46 per share. | 17 May 2023 | 345 | 915,391 (4%) | 0% | 35.5 | 12,234 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 35.46 per share. | 17 May 2023 | 1,320 | 427,227 (2%) | 0% | 35.5 | 46,810 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.33 per share. | 03 May 2023 | 865 | 231,559 (1%) | 0% | 29.3 | 25,370 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.33 per share. | 03 May 2023 | 6,198 | 428,547 (2%) | 0% | 29.3 | 181,787 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.90 per share. | 01 May 2023 | 775 | 434,745 (2%) | 0% | 29.9 | 23,173 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 29.57 per share. | 30 Apr 2023 | 76 | 915,736 (4%) | 0% | 29.6 | 2,247 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.85 per share. | 01 Mar 2023 | 433 | 236,229 (1%) | 0% | 31.8 | 13,791 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.85 per share. | 01 Mar 2023 | 3,805 | 232,424 (1%) | 0% | 31.8 | 121,189 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.85 per share. | 01 Mar 2023 | 3,804 | 915,812 (4%) | 0% | 31.8 | 121,157 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.85 per share. | 01 Mar 2023 | 4,045 | 435,520 (2%) | 0% | 31.8 | 128,833 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 32.67 per share. | 27 Feb 2023 | 433 | 439,565 (2%) | 0% | 32.7 | 14,146 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 7,616 | 603,787 (3%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 47,393 | 651,180 (3%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.65 per share. | 23 Feb 2023 | 2,625 | 648,555 (3%) | 0% | 31.6 | 83,081 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 2,142 | 223,185 (1%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.65 per share. | 23 Feb 2023 | 741 | 236,662 (1%) | 0% | 31.7 | 23,453 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 14,218 | 237,403 (1%) | 0% | 0 | Common Stock | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 12,156 | 920,410 (4%) | 0% | 0 | Common Stock | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 2,142 | 908,254 (4%) | 0% | 0 | Common Stock | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.65 per share. | 23 Feb 2023 | 794 | 919,616 (4%) | 0% | 31.6 | 25,130 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 31.65 per share. | 23 Feb 2023 | 741 | 439,998 (2%) | 0% | 31.7 | 23,453 | Common Stock |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 14,573 | 440,739 (2%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 2,142 | 426,166 (2%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.99 per share. | 15 Feb 2023 | 1,019 | 221,043 (1%) | 0% | 34.0 | 34,636 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.99 per share. | 15 Feb 2023 | 321 | 222,062 (1%) | 0% | 34.0 | 10,911 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.99 per share. | 15 Feb 2023 | 383 | 906,112 (4%) | 0% | 34.0 | 13,018 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.99 per share. | 15 Feb 2023 | 1,018 | 424,024 (2%) | 0% | 34.0 | 34,602 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.21 per share. | 03 Feb 2023 | 1,020 | 222,383 (1%) | 0% | 36.2 | 36,934 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 36.21 per share. | 03 Feb 2023 | 4,408 | 425,042 (2%) | 0% | 36.2 | 159,614 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 34.75 per share. | 01 Feb 2023 | 624 | 429,450 (2%) | 0% | 34.8 | 21,684 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 33.04 per share. | 30 Jan 2023 | 90 | 906,495 (4%) | 0% | 33.0 | 2,974 | Common Stock |
| Ms. Regina E. Groves | Director | 03 Jan 2023 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | ||
| Ms. Regina E. Groves | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jan 2023 | 4,000 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 35.33 per share. | 02 Dec 2022 | 653 | 223,403 (1%) | 0% | 35.3 | 23,070 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 34.39 per share. | 30 Nov 2022 | 685 | 430,074 (2%) | 0% | 34.4 | 23,559 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 35.89 per share. | 16 Nov 2022 | 490 | 224,056 (1%) | 0% | 35.9 | 17,586 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 35.89 per share. | 16 Nov 2022 | 1,306 | 224,546 (1%) | 0% | 35.9 | 46,873 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 35.89 per share. | 16 Nov 2022 | 342 | 906,585 (4%) | 0% | 35.9 | 12,275 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 35.89 per share. | 16 Nov 2022 | 1,306 | 430,759 (2%) | 0% | 35.9 | 46,873 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 39.02 per share. | 07 Nov 2022 | 220,816 | 220,816 (1%) | 1% | 39.0 | 8,615,357 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 39.02 per share. | 07 Nov 2022 | 566,171 | 596,171 (3%) | 3% | 39.0 | 22,089,728 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2022 | 77,585 | 225,852 (1%) | 0% | 0 | Common Stock | |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2022 | 51,723 | 906,927 (4%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2022 | 220,816 | 220,816 (1%) | 1% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Nov 2022 | 129,309 | 432,065 (2%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 37.89 per share. | 03 Nov 2022 | 1,240 | 148,267 (0%) | 0% | 37.9 | 46,984 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 37.89 per share. | 03 Nov 2022 | 6,198 | 302,756 (1%) | 0% | 37.9 | 234,842 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 40.25 per share. | 01 Nov 2022 | 775 | 308,954 (1%) | 0% | 40.3 | 31,194 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 40.28 per share. | 30 Oct 2022 | 76 | 855,204 (4%) | 0% | 40.3 | 3,061 | Common Stock |
| Mr. Ming Hsieh | Director, Chief Executive Officer, Ten Percent Owner | 14 Sep 2022 | 800,000 | 800,000 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 41.39 per share. | 06 Sep 2022 | 662 | 149,507 (0%) | 0% | 41.4 | 27,403 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 44.18 per share. | 30 Aug 2022 | 675 | 309,729 (1%) | 0% | 44.2 | 29,824 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 48.89 per share. | 17 Aug 2022 | 1,945 | 150,169 (0%) | 0% | 48.9 | 95,100 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 48.89 per share. | 17 Aug 2022 | 370 | 855,280 (4%) | 0% | 48.9 | 18,091 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 48.89 per share. | 17 Aug 2022 | 1,414 | 310,404 (1%) | 0% | 48.9 | 69,137 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.93 per share. | 03 Aug 2022 | 1,048 | 152,114 (0%) | 0% | 62.9 | 65,951 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 62.93 per share. | 03 Aug 2022 | 6,343 | 311,818 (1%) | 0% | 62.9 | 399,165 | Common Stock |
| Dr. Leonard E. Post, PhD | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2022 | 8,000 | 8,000 (0%) | 0% | 0 | Common Stock | |
| Mr. Ming Hsieh | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2022 | 30,000 | 30,000 (0%) | 0% | 0 | Common Stock | |
| Mr. John C. Bolger | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2022 | 1,600 | 5,100 (0%) | 0% | 0 | Common Stock | |
| Ms. Linda Marsh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2022 | 1,600 | 5,600 (0%) | 0% | 0 | Common Stock | |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.54 per share. | 01 Aug 2022 | 872 | 318,161 (1%) | 0% | 59.5 | 51,919 | Common Stock |
| Mr. Michael Nohaile | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2022 | 4,000 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Mr. Michael Nohaile | Director | 01 Aug 2022 | 10,000 | 10,000 | - | - | Stock Option (Right to Buy) | ||
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 59.75 per share. | 30 Jul 2022 | 87 | 855,650 (4%) | 0% | 59.7 | 5,198 | Common Stock |
| Mr. Ming Hsieh | Director, President and CEO, Ten Percent Owner | 08 Jun 2022 | 1,000,000 | 1,000,000 | - | - | Forward sale contract (obligation to sell) | ||
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 55.10 per share. | 02 Jun 2022 | 415 | 153,162 (0%) | 0% | 55.1 | 22,867 | Common Stock |
| Mr. John C. Bolger | Director | 31 May 2022 | 313 | 1,250 | - | - | Stock Option (Right to Buy) | ||
| Mr. John C. Bolger | Director | 31 May 2022 | 313 | 0 | - | - | Stock Option (Right to Buy) | ||
| Mr. John C. Bolger | Director | Sale of securities on an exchange or to another person at price $ 55.25 per share. | 31 May 2022 | 500 | 3,500 (0%) | 0% | 55.3 | 27,625 | Common Stock |
| Mr. John C. Bolger | Director | Sale of securities on an exchange or to another person at price $ 55.43 per share. | 31 May 2022 | 313 | 4,000 (0%) | 0% | 55.4 | 17,351 | Common Stock |
| Mr. John C. Bolger | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.81 per share. | 31 May 2022 | 313 | 4,313 (0%) | 0% | 5.8 | 1,818 | Common Stock |
| Mr. John C. Bolger | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.93 per share. | 31 May 2022 | 313 | 4,313 (0%) | 0% | 3.9 | 1,229 | Common Stock |
| Mr. John C. Bolger | Director | Sale of securities on an exchange or to another person at price $ 55.32 per share. | 31 May 2022 | 313 | 4,000 (0%) | 0% | 55.3 | 17,315 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 54.54 per share. | 31 May 2022 | 668 | 319,033 (1%) | 0% | 54.5 | 36,433 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 58.29 per share. | 19 May 2022 | 10,000 | 319,701 (1%) | 0% | 58.3 | 582,866 | Common Stock |
| Mr. John C. Bolger | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2022 | 2,000 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Dr. Yun Yen, M.D. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2022 | 2,000 | 2,000 (0%) | 0% | 0 | Common Stock | |
| Ms. Linda Marsh | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2022 | 2,000 | 4,000 (0%) | 0% | 0 | Common Stock | |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 866 | 153,577 (0%) | 0% | 53.4 | 46,229 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 325 | 154,443 (0%) | 0% | 53.4 | 17,349 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 325 | 855,737 (4%) | 0% | 53.4 | 17,349 | Common Stock |
| Mr. Jian Xie | President and COO | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 1,269 | 329,701 (1%) | 0% | 53.4 | 67,742 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 325 | 855,737 (3%) | 0% | 53.4 | 17,349 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 325 | 154,443 (0%) | 0% | 53.4 | 17,349 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 866 | 153,577 (0%) | 0% | 53.4 | 46,229 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 866 | 153,577 (0%) | 0% | 53.4 | 46,229 | - |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 325 | 154,443 (0%) | 0% | 53.4 | 17,349 | - |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 53.38 per share. | 16 May 2022 | 325 | 855,737 (3%) | 0% | 53.4 | 17,349 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.69 per share. | 03 May 2022 | 806 | 154,768 (0%) | 0% | 56.7 | 45,692 | - |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.69 per share. | 03 May 2022 | 806 | 154,768 (0%) | 0% | 56.7 | 45,692 | Common Stock |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.69 per share. | 03 May 2022 | 5,904 | 330,970 (1%) | 0% | 56.7 | 334,698 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 56.69 per share. | 03 May 2022 | 806 | 154,768 (0%) | 0% | 56.7 | 45,692 | - |
| Mr. Jian Xie | President and COO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 54.88 per share. | 01 May 2022 | 738 | 336,874 (1%) | 0% | 54.9 | 40,501 | Common Stock |
| Mr. Han Lin Gao, M.D. | Chief Scientific Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 54.88 per share. | 30 Apr 2022 | 283 | 856,062 (4%) | 0% | 54.9 | 15,531 | Common Stock |
| Mr. Paul Kim | CFO and Treasurer | Sale of securities on an exchange or to another person at price $ 56.31 per share. | 03 Mar 2022 | 454 | 155,574 (0%) | 0% | 56.3 | 25,564 | Common Stock |