What is Prothena Corporation plc Quarterly Revenue?

Prothena Corporation plc Quarterly Revenue Prothena Corporation plc Jun-2026 Quarterly Revenue is $1 Million which is growth of -77.1% YoY.

What is Prothena Corporation plc Quarterly Net Profit?

Prothena Corporation plc Quarterly Net Profit Prothena Corporation plc Jun-2026 Quarterly Net Profit is $-19 Million which is growth of 85.2% YoY.

What is Prothena Corporation plc Annual Revenue?

Prothena Corporation plc Annual Revenue Prothena Corporation plc Dec-2025 Annual Revenue is $10 Million which is growth of -92.8% YoY.

What is Prothena Corporation plc Annual Net Profit?

Prothena Corporation plc Annual Net Profit Prothena Corporation plc Dec-2025 Annual Net Profit is $-244 Million which is growth of -99.6% YoY.

What is Prothena Corporation plc Total Shareholders Fund?

Prothena Corporation plc Total Shareholders Fund Prothena Corporation plc Dec-2025 Total Shareholders Fund is $280 Million which is growth of -42.4% YoY.

What is Prothena Corporation plc Total Assets?

Prothena Corporation plc Total Assets Prothena Corporation plc Dec-2025 Total Assets is $327 Million which is growth of -40.3% YoY.

What is Prothena Corporation plc Book Value Per Share?

Prothena Corporation plc Book Value Per Share Prothena Corporation plc Book Value Per Share is $6 which is growth of -7.2% YoY.

What is Prothena Corporation plc ROE?

Prothena Corporation plc ROE Prothena Corporation plc ROE is 0% which is growth of 0% YoY.

What is Prothena Corporation plc Cash From Operating Activity?

Prothena Corporation plc Cash From Operating Activity Prothena Corporation plc Dec-2025 Cash From Operating Activity is $-164 Million which is growth of -9.0% YoY.

What is Prothena Corporation plc Net Cash Flow?

Prothena Corporation plc Net Cash Flow Prothena Corporation plc Dec-2025 Net Cash Flow is $-164 Million which is growth of -10.1% YoY.

Prothena Corporation plc

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Prothena Corporation plc quarterly and annual earnings report: results, revenue, profit, P&L, balance sheet, cash flow, financial ratios, revenue mix, peer comparison, and financial documents

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Forecaster Analyst Estimates for Prothena Corporation plc share price target, revenues, EPS, net income and more

Prothena Corporation plc quarterly results: revenue, profit, and P&L – 13 quarter history

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NEGATIVE
Quarterly Revenue Prothena Corporation plc Jun-2026 Quarterly Revenue is $1 Million which is growth of -77.1% YoY.
POSITIVE
Quarterly Net Profit Prothena Corporation plc Jun-2026 Quarterly Net Profit is $-19 Million which is growth of 85.2% YoY.

Prothena Corporation plc, Earnings Report - Quarterly Results, standalone, All financials are in USD Million and price data in USD
Indicator	Jun '26	Mar '26	Dec '25	Sep '25	Jun '25	Mar '25	Dec '24	Sep '24	Jun '24	Mar '24	Dec '23	Sep '23	Jun '23
SR_Q Operating Rev.	1	51.1	0	2.4	4.4	2.8	2.1	1	132	0.1	0.3	84.9	4
CostOfRevenue_Q Cost Of Rev.	-	-	-	-	-	-	-	-	-	-	-	-	-
GrossProfit_Q Gross Profit	-	-	-	-	-	-	-	-	-	-	-	-	-
OEXPNS_Q Operating Exp. ⌄	19.7	25.3	27.2	42.2	56.4	68.4	67	67.5	73.6	81.6	78.8	74.6	70.5
AdminAndSellingExpenses_Q Admin Plus Selling Exp.	10.9	12.7	12.7	13.2	15.9	17.6	16.9	16.8	16.1	17.5	16.9	16.6	14.5
ResearchAndDevlopmentExpenses_Q RnD Exp.	8.8	12.6	14.6	28.9	40.5	50.8	50.2	50.7	57.5	64.1	61.9	57.9	56
OP_Q Operating Profit	-18.7	25.8	-27.2	-39.8	-52	-65.6	-64.9	-66.5	58.4	-81.5	-78.5	10.3	-66.5
NetNonOperIntIncExp_Q Net Non Operations Interest Incuding Expenses ⌄	2.6	2.4	2.7	3.4	3.8	4.4	5.4	6.7	6.5	7.2	8.1	8.5	7.7
Others_Q Other Interest Earned	2.6	2.4	2.7	3.4	3.8	4.4	5.4	6.7	6.5	7.2	8.1	8.5	7.7
IntExpNonOperating_Q Interest Exp. Non Operating	-	-	-	-	-	-	-	-	-	-	-	-	-
PBT_Q Profit Before Tax	-18.6	32.7	-21.6	-36.9	-81	-61.4	-59.5	-59.8	64.9	-74.4	-70.6	18.8	-58.9
TAX_Q Tax			0	-0.4	44.8	-1.2	-1.5	-0.8	-2	-2.2	-3.1	-3.1	-4.3
NICommonStockholders_Q Net Income Common Stockholders ⌄	-18.6	32.7	-21.6	-36.5	-125.8	-60.2	-58	-59	66.9	-72.2	-67.5	21.9	-54.6
NP_Q Net Profit	-18.6	32.7	-21.6	-36.5	-125.8	-60.2	-58	-59	66.9	-72.2	-67.5	21.9	-54.6
NIIncludingNoncontrollingInterests_Q Net Income Including Non controlling Interests	-18.6	32.7	-21.6	-36.5	-125.8	-60.2	-58	-59	66.9	-72.2	-67.5	21.9	-54.6
DilutedNIAvailtoComStockholders_Q Diluted NI Avail to Com Stockholders Ann.	-18.6	32.7	-21.6	-36.5	-125.8	-60.2	-58	-59	66.9	-72.2	-67.5	21.9	-54.6
EPS_Q Basic EPS	-0.4	0.6	-0.4	-0.7	-2.3	-1.1	-1.1	-1.1	1.2	-1.3	-1.3	0.4	-1
AfterDilutedEPS_Q Diluted EPS After ExtraOrdinary	-0.3	0.5	-0.4	-0.7	-1.8	-1.1	-1.1	-1.1	1.2	-1.3	-1.3	0.4	-1
SHARE_Q Number Of Shares End	52.1	53.7	53.8	53.8	53.8	53.8	53.8	53.8	53.8	53.7	53.7	53.6	53.1
NIContinuingDiscontinuedOper_Q Net Income Continuing Discontinued Operations	-18.6	32.7	-21.6	-36.5	-125.8	-60.2	-58	-59	66.9	-72.2	-67.5	21.9	-54.6
NormalizedIncome_Q Normalized Income	-9.6	35.4	-17.9	-28.9	-86.4	-49.5	-47.7	-48.1	77.4	-60.2	-56.9	31.5	-45.2
InterestIncome_Q Interest Income	2.6	2.4	2.7	3.4	3.8	4.4	5.4	6.7	6.5	7.2	8.1	8.5	7.7
INT_Q Interest	-	-	-	-	-	-	-	-	-	-	-	-	-
NetInterestIncome_Q Net Interest Income	2.6	2.4	2.7	3.4	3.8	4.4	5.4	6.7	6.5	7.2	8.1	8.5	7.7
EBIT_Q EBIT	-21.1	30.3	-24.2	-40.3	-84.8	-65.7	-64.9	-66.6	58.3	-81.6	-78.7	10.3	-66.6
EBITDA_Q EBITDA	-20.9	30.5	-24	-40.1	-84.6	-65.5	-64.7	-66.4	58.5	-81.4	-78.7	10.5	-66.4
ReconciledCostOfRevenue_Q Reconciled Cost Of Rev.	-	-	-	-	-	-	-	-	-	-	-	-	-
ReconciledDepreciation_Q Reconciled Depr.	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	-5	5.5	0.2
ProfitLossFromContinuingOperations_Q Profit From Continuing Operations	-18.6	32.7	-21.6	-36.5	-125.8	-60.2	-58	-59	66.9	-72.2	-67.5	21.9	-54.6
NormalizedEBITDA_Q Normalized EBITDA	-16.1	21.7	-29.7	-39.1	-19.2	-65.4	-64.7	-66.3	58.6	-81.3	-78.5	15.8	-66.3

*All financials are in USD Million and price data in USD

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Prothena Corporation plc competitor comparison and performance snapshot within industry

Prothena Corporation plc annual results: revenue, profit, P&L, and margins as of Dec 2025 – 11 year history

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NEGATIVE
Annual Revenue Prothena Corporation plc Dec-2025 Annual Revenue is $10 Million which is growth of -92.8% YoY.
NEGATIVE
Annual Net Profit Prothena Corporation plc Dec-2025 Annual Net Profit is $-244 Million which is growth of -99.6% YoY.

Prothena Corporation plc, Earnings Report - Annual Results, standalone, All financials are in USD Million and price data in USD
Indicator	CAGR 3 Yrs	CAGR 5 Yrs	TTM	Dec '25	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
SR_A Total Rev. Ann. ⌄	-43.5%	60.9%		9.7	135.2	91.4	53.9	200.6	0.9	0.8	1	27.5	1.1	1.6
TotalOperatingRevenues_A Operating Rev. Ann.	-43.5%	60.9%	54.5	9.7	135.2	91.4	53.9	200.6	0.9	0.8	1	27.5	1.1	1.6
CostOfRevenue_A Cost Of Rev. Ann.	-	-		-	-	-	-	-	-	-	-	-	-	-
GrossProfit_A Gross Profit Ann.	-	-		-	-	-	-	-	-	-	-	-	-	-
OEXPNS_A Operating Exp. Ann.	1.5%	11.3%	114.4	194.2	289.7	282.4	185.5	128.6	113.6	86.6	143.7	182.8	160.6	81.5
OP_A Operating Profit Ann.	-	-	-59.9	-184.6	-154.6	-191	-131.6	72	-112.7	-85.8	-142.7	-155.3	-159.5	-79.9
NetNonOperIntIncExp_A Net Non Operations Interest Incuding Expenses Ann, ⌄	30.1%	58.7%	11	14.1	25.8	31	6.4	0	1.4	8.2	2.7	-0.1	0.6	0.2
Others_A Other Interest Earned Ann.	30.1%	58.7%	11	14.1	25.8	31	6.4	0	1.4	8.2	6.4	3.6	-	0.2
IntExpNonOperating_A Interest Exp. Non Operating Ann.	-	-		-	-	-	-	-	-		3.7	3.7	-	-
OtherExpenses_A Other Exp. Ann.	-	-		-30.4	-0.2	-0.5	-0.4	-0.1	-0.1	0.3	-16.1	-2.2	0	-0.2
PBT_A PBT Ann.	-	-	-44.4	-200.8	-128.9	-160.5	-125.6	71.9	-111.4	-77.3	-156.1	-157.6	-159	-79.9
TAX_A Tax Ann.	-	-	-0.4	43.3	-6.6	-13.5	-8.7	5	-0.3	0.4	-0.5	-4.4	1.1	0.7
NICommonStockholders_A Net Income Common Stockholders Ann. ⌄	-	-	-44	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.7	-153.2	-160.1	-80.6
NP_A Net Profit Ann.	-	-	-44	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.6	-153.2	-160.1	-80.6
NIIncludingNoncontrollingInterests_A Net Income Including Non controlling Interests Ann.	-	-	-44	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.7	-153.2	-160.1	-80.6
DilutedNIAvailtoComStockholders_A Diluted NI Avail to Com Stockholders Ann.	-	-	-44	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.7	-153.2	-160.1	-80.6
EPS_A EPS Ann.	-	-		-4.5	-2.3	-2.8	-2.5	1.5	-2.8	-2	-3.9	-4.1	-4.7	-2.7
DilutedEPS_A Diluted EPS Ann.	-	-		-4.5	-2.3	-2.8	-2.5	1.4	-2.8	-2	-3.9	-4.1	-4.7	-2.7
SHARE_Q Number Of Shares End	3.2%	6.2%		53.8	53.8	53.7	49	46.7	39.9	39.9	39.9	38.5	34.6	31.6
TotalExpenses_A Total Exp. Ann.	1.5%	11.3%		194.2	289.7	282.4	185.5	128.6	113.6	86.6	143.7	182.8	160.6	81.5
NIContinuingDiscontinuedOper_A Net Income Continuing Discontinued Operations Ann.	-	-	-44	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.7	-153.2	-160.1	-80.6
NormalizedIncome_A Normalized Income Ann.	-	-	-21.1	-184.8	-78.7	-109.5	-87.8	89.9	-89.2	-57.1	-112	-127.2	-138.3	-71.5
InterestIncome_A Interest Income Ann.	30.1%	58.7%	11	14.1	25.8	31	6.4	0	1.4	8.2	6.4	3.6	-	0.2
INT_A Interest Ann.	-	-		-	-	-	-	-	-		3.7	3.7	-	-
EBITDA_A EBITDA Ann.	-	-	-54.5	-214.1	-153.9	-190.6	-131.2	78.7	-105.8	-78.7	-155.6	-154.4	-157.1	-79.3
ReconciledCostOfRevenue_A Reconciled Cost Of Rev. Ann.	-	-		-	-	-	-	-	-	-	-	-	-	-
ReconciledDepreciation_A Reconciled Depr. Ann.	8.7%	-33.7%	0.8	0.9	0.9	0.9	0.7	6.8	7	6.8	3.2	3.1	2.4	0.8
ProfitLossFromContinuingOperations_A Profit From Continuing Operations Ann.	-	-	-44	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.6	-153.2	-160.1	-80.6
NormalizedEBITDA_A Normalized EBITDA Ann.	-	-	-63.1	-153.3	-153.5	-190.1	-130.8	78.8	-105.8	-70.5	-133.1	-150.9	-157.1	-79.1

*All financials are in USD Million and price data in USD

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Total Rev. Ann.

1Y CHG

-92.8%

2Y CAGR

-67.4%

3Y CAGR

-43.5%

5Y CAGR

60.9%

7Y CAGR

38.3%

10Y CAGR

19.7%

Total Revenue Annual is falling faster than historical averages.

Operating Exp. Ann.

1Y CHG

-33%

2Y CAGR

-17.1%

3Y CAGR

1.5%

5Y CAGR

11.3%

7Y CAGR

4.4%

10Y CAGR

9.1%

Operating Expenses Annual Cr is falling faster than historical averages.

Prothena Corporation plc balance sheet as of Dec 2025: assets, liabilities, reserves, and borrowings – 11 year history

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NEGATIVE
Total Shareholders Fund Prothena Corporation plc Dec-2025 Total Shareholders Fund is $280 Million which is growth of -42.4% YoY.
NEGATIVE
Total Assets Prothena Corporation plc Dec-2025 Total Assets is $327 Million which is growth of -40.3% YoY.

Prothena Corporation plc, Balance Sheet, standalone, All financials are in USD Million and price data in USD
Indicator	CAGR 3 Yrs	CAGR 5 Yrs	Dec '25	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
TA_A Total Assets Ann. ⌄	-24.5%	-0.4%	326.8	547.1	696.4	758	609.4	333	419.3	498.8	496.3	460	385.2
CA_A Total Current Assets Ann.	-24%	1%	315.2	485.4	639.3	719.1	584.8	299.3	378.4	431.4	426.3	391.4	377.4
CashEquivalentsShortTermInvestments_A Cash Equivalents and Short Term Investments Ann.	-24.4%	0.8%	307.5	471.4	618.8	710.4	579.1	295.4	375.7	427.7	417.6	386.9	370.6
Receivables_A Change In Account Receivables Ann.	-	-	-		5.2	0.1		0	0.1		0.2	0.2	0.5
Inventories_A Inventories Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
OtherCurrentAssets_A Other Current Assets Ann.	1.9%	-6.4%	1.8	1.2	2.1	1.7	5.7	2.5	-	3.7	8.5	4.3	6.3
TotalNonCurrentAssets_A Total Non Current Assets Ann.	-33.2%	-19.2%	11.6	61.7	57.1	38.9	24.6	33.7	40.9	67.4	70	68.6	7.8
NetPPE_A Net PPE Ann.	8.8%	-12.8%	10.3	13.8	16	8	14.1	20.4	27.2	52.8	55	56.5	3.9
InvestmentsAndAdvances_A Investments & Advances Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
OtherNonCurrentAssets_A Other Non Current Assets Ann.	-53.2%	-5.2%	1.3	4.7	7.2	12.7	3.4	1.7	3.8	4.9	6.9	6.3	1.1
TotalLiabilitiesNetMinorityInterest_A Total Liabilities Net Minority Interest Ann. ⌄	-30.2%	-20.8%	46.3	60.2	135	136	143.3	149	146.4	175.8	89.1	94.6	24.6
CL_A Total Current Liabilities Ann.	-6.7%	9.5%	40.8	48.5	56.9	50.2	33.5	25.9	17.7	14.9	37.4	41.1	22.2
PayablesAndAccruedExpenses_A Payables & Accrued Exp.s Ann.	-12%	1.8%	21.6	35.7	53.7	31.7	19.5	19.8	12.3	12.5	35.2	39.6	21.4
CurrentDebtCapLeaseObligation_A Current Debt Cap Lease Obligation Ann.	-23.6%	-12%	2.9	2.6	1.1	6.5	5.9	5.5	5.1	1.7	0.7	-	-
CurrentDeferredLiabilities_Q Current Deferred Liabilities	-38.1%	-	2.7	8.9		11.4	7.7	-		0	0.1	0.4	0.3
OtherCurrentLiabilities_A Other Current Liabilities Ann.	201.5%	93.9%	13.7	1.4	2.1	0.5	0.4	0.5	0.3	0.7	1.4	1.1	0.5
TotalNonCurrentLiabilities_A Total Non Current Liabilities Ann.	-60%	-46.3%	5.5	11.7	78.1	85.9	109.9	123.1	128.6	160.9	51.8	53.5	2.4
LongTermDebtAndCapitalLeaseObligation_Q LT Debt & Capital Lease Obligation	-	-14.9%	5.5	8.2	10.7		6.4	12.3	17.8	49.9	51.5	51.3	-
TradeandOtherPayablesNonCurrent_A Trade & Other Payables Non Current Ann.	-	-	-	-	-	-	-	-	-	-	-	0.1	0.1
TotalDeferredCreditsAndOtherNonCurrentLiabilities_A Total Deferred Credits & Other Non Current Liabilities Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
TotalShareHoldersFunds_A Total ShareHolders Funds Ann. ⌄	-23.3%	8.8%	280.5	486.9	561.4	622	466	184	272.9	323	407.2	365.4	360.7
EQCAP_A Equity Share Capital Ann.	-23.3%	8.8%	280.5	486.9	561.4	622	466	184	272.9	323	407.2	365.4	360.7
CapitalStock_A Capital Stock Ann.	0%	4.6%	0.5	0.5	0.5	0.5	0.5	0.4	0.4	0.4	0.4	0.4	0.3
RetainedEarnings_A Retained Earnings Ann.	-	-	-1,346.4	-1,102.3	-980	-833	-716.1	-783	-671.9	-598	-442.4	-289.2	-129.1
GainsLossesNotAffectingRetainedEarnings_A Gains Losses Not Affecting Retained Earnings Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
TotalCapitalization_A Total Capitalization Ann.	-23.3%	8.8%	280.5	486.9	561.4	622	466	184	272.9	323	407.2	365.4	360.7
TangibleAssets_A Tangible Assets Ann.	-23.3%	8.8%	280.5	486.9	561.4	622	466	184	272.9	323	407.2	365.4	360.7
WC_A Working Capital Ann.	-25.7%	0.1%	274.4	436.9	582.4	669	551.4	273.4	360.7	416.5	389	350.3	355.2
InvestedCapital_A Invested Capital Ann.	-23.3%	8.8%	280.5	486.9	561.4	622	466	184	272.9	323	407.2	365.4	360.7
TangibleBookValue_A Tangible Book Value Ann.	-23.3%	8.8%	280.5	486.9	561.4	622	466	184	272.9	323	407.2	365.4	360.7
Borrowings_A Borrowings Ann.	8.9%	-13.9%	8.4	10.8	11.8	6.5	12.3	17.8	22.9	51.6	52.3	51.3	-
NetDebt_A Net Debt Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
ShareIssued_A Share Issued Ann.	1.1%	6.2%	53.8	53.8	53.7	52.1	46.7	39.9	39.9	39.9	38.5	34.8	31.7
SHARE_Q Number Of Shares End	3.2%	6.2%	53.8	53.8	53.7	49	46.7	39.9	39.9	39.9	38.5	34.6	31.6

*All financials are in USD Million and price data in USD

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Total Assets Ann.

1Y CHG

-40.3%

2Y CAGR

-31.5%

3Y CAGR

-24.5%

5Y CAGR

-0.4%

7Y CAGR

-5.9%

10Y CAGR

-1.6%

Total Assets Annual is falling faster than historical averages.

Total Current Liabilities Ann.

1Y CHG

-15.9%

2Y CAGR

-15.3%

3Y CAGR

-6.7%

5Y CAGR

9.5%

7Y CAGR

15.5%

10Y CAGR

6.3%

Total Current Liabilities Annual Cr is falling faster than historical averages.

Total ShareHolders Funds Ann.

1Y CHG

-42.4%

2Y CAGR

-29.3%

3Y CAGR

-23.3%

5Y CAGR

8.8%

7Y CAGR

-2%

10Y CAGR

-2.5%

Total ShareHolders Funds Annual is falling faster than historical averages.

Prothena Corporation plc ROE, ROCE, book value, and debt-to-equity ratio as of Dec 2025 – 11 year history

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NEGATIVE
Book Value Per Share Prothena Corporation plc Book Value Per Share is $6 which is growth of -7.2% YoY.
NEUTRAL
ROE Prothena Corporation plc ROE is 0% which is growth of 0% YoY.

Prothena Corporation plc, Ratios, standalone, All financials are in USD Million and price data in USD
Indicator	CAGR 3 Yrs	CAGR 5 Yrs	Dec '25	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
ROA_A RoA Ann. %	-	-	-	-19.67%	-20.22%	-17.11%	14.21%	-29.55%	-16.92%	-31.28%	-32.05%	-37.89%	-23.39%
ROE_A ROE Ann. %	-	-	-	-23.34%	-24.85%	-21.50%	20.61%	-48.65%	-26.07%	-42.63%	-39.67%	-44.10%	-24.78%
ROIC_Q ROIC %	-	-	-	-12.1	-12.5	0.6	-6.8	-14.3	-7.6	-6.1	-10	-11.4	-6.6
OPMPCT_A OPM Ann. %	-	-	-1,905.82%	-114.36%	-209.08%	-244.05%	35.88%	-13,216.18%	-10,535.38%	-14,943.46%	-564.17%	-15,121.80%	-4,974.30%
NBTO_A Inventory Turnover Ratio Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
ASETTO_A Asset Turnover Ann. %	-	-	-	0.2	0.1	0.1	0.4				0.1
WCTO_A Working Capital Turnover Ann.	-	-	0	0.3	0.2	0.1	0.4				0.1
QuickRatio_A Quick Ratio Ann.	-	-	-	9.7	11	14.2	17.3	11.4	21.2	28.7	11.2	9.4	16.7
CRATIO_A Current Ratio Ann.	-	-	-	10	11.2	14.3	17.5	11.6	21.4	28.9	11.4	9.5	17
IC_A Interest Coverage Ratio Ann.	-	-	-	-	-	-	-	-	-	-41.2	-41.7	-	-
LTDE_A LT Debt To Equity Ann.	-	-	-	0	0	-	0	0.1	0.1	0.2	0.1	0.1	-

*All financials are in USD Million and price data in USD

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Prothena Corporation plc cash flow: net, operating, investing, and financing flows as of Dec 2025 – 11 year history

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NEGATIVE
Cash From Operating Activity Prothena Corporation plc Dec-2025 Cash From Operating Activity is $-164 Million which is growth of -9.0% YoY.
NEGATIVE
Net Cash Flow Prothena Corporation plc Dec-2025 Net Cash Flow is $-164 Million which is growth of -10.1% YoY.

Prothena Corporation plc, Cash Flow, standalone, All financials are in USD Million and price data in USD
Indicator	CAGR 3 Yrs	CAGR 5 Yrs	Dec '25	Dec '24	Dec '23	Dec '22	Dec '21	Dec '20	Dec '19	Dec '18	Dec '17	Dec '16	Dec '15
CFO_A Cash from Operating Act. Ann. ⌄	-	-	-163.6	-150.1	-133.9	-108.8	92.6	-80.4	-53	-28.3	-131.2	-117.3	-62.5
ProfitLossFromContinuingOperations_A Profit From Continuing Operations Ann.	-	-	-244.1	-122.3	-147	-117	67	-111.1	-77.7	-155.6	-153.2	-160.1	-80.6
DepreciationAmortizationDepletion_A Depreciation Amortization Depletion Ann.	8.7%	-33.7%	0.9	0.9	0.9	0.7	6.8	7	6.8	3.2	3.1	2.4	0.8
DepreciationAndAmortization_A Depreciation And Amortization Ann.	8.7%	-33.7%	0.9	0.9	0.9	0.7	6.8	7	6.8	3.2	3.1	2.4	0.8
DeferredTax_A Deferred Tax Ann.	-	-	43.2	-9.4	-15.7	-11.1	4.6	-1.7	-1.3	-1.6	-2.2	-3.3	-1
DeferredIncomeTax_A Deferred Income Tax Ann.	-	-	43.2	-9.4	-15.7	-11.1	4.6	-1.7	-1.3	-1.6	-2.2	-3.3	-1
EmployeesStockOptions_A ESOPs Ann.	6.3%	11.3%	37.6	46	40.9	31.3	24.7	22	23.6	27	26.8	24.9	10.4
OtherNonCashItems_A Other Non Cash Items Ann.	-22.4%	-	2.8	2.7	7.5	6	-	-	-	3.7	1.6	0.9	0.3
ChangeInWorkingCapital_A Change In Working Capital Ann.	-	-	-4.2	-67.9	-20.5	-18.8	-10.4	3.5	-4.5	94.5	-7.2	18.9	11.5
ChangeInReceivables_A Change In Receivables Ann.	-	-		5.2	-5.2	-	0	0.1	-	0.2	-0.1	0.3	1.3
ChangeInInventory_A Change In Inventory Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
ChangePayablesAccruedExpense_A Change Payables Accrued Expense Ann.	-	-	-15.8	-18.3	22.9	11.9	-0.5	7.7	-0.1	-25.6	0.2	15.2	11.2
ChangeInOtherCurrentAssets_A Change In Other Current Assets Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-0.9
ChangeInOtherCurrentLiabilities_A Change In Other Current Liabilities Ann.	-	-	10.6	-2.2	-6.4	-6	-5.5	-5.1	-5.2	0.5	-	-	-
ChangeInOtherWorkingCapital_A Change In Other Working Capital Ann.	-	-	-9.6	-55.1	-29.3	-13.9	0.4	-	-	110.2	-	-	-
CFI_A Cash from Investing Act. Ann. ⌄	-	-	-0.1	-0.3	-2.8	-0.5	-0.6	-0.2	-0.6	-1.7	-3.5	-16.6	-1.4
NetPPEPurchaseAndSale_A Net PPE Purchase & Sale Ann.	-	-	-0.1	-0.3	-2.8	-0.5	-0.6	-0.2	-0.6	-1.7	-3.5	-16.6	-1.4
PurchaseOfPPE_A Purchase Of PPE Ann.	-	-	-0.1	-0.3	-2.8	-0.5	-0.6	-0.2	-0.6	-1.8	-3.6	-16.6	-1.4
NetBusinessPurchaseAndSale_A Net Business Purchase & Sale Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
PurchaseOfBusiness_A Purchase Of Business Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
PurchaseOfInvestment_A Purchase Of Investment Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
SaleOfInvestment_A Sale Of Investment Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
NetOtherInvestingChanges_A Net Other Investing Changes Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
CFA_A Cash from Financing Act. Ann. ⌄	-	-	-0.1	1.6	45.1	241.5	190.3	0.2	0.2	40	165.4	154.3	140.8
NetIssuancePaymentsOfDebt_A Net Issuance Payments Of Debt Ann.	-	-	-	-	-	-	-		-	-4.4	-2.8	-0.2	-
NetLongTermDebtIssuance_A Net Long Term Debt Issuance Ann.	-	-	-	-	-	-	-		-	-4.4	-2.8	-0.2	-
NetShortTermDebtIssuance_A Net ST Debt Issuance Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
NetCommonStockIssuance_A Net Common Stock Issuance Ann.	-	-	-0.1	-0.4	23.6	223.6	174.8		-	39.8	150.3	128.8	131.3
CommonStockIssuance_A Common Stock Issuance Ann.	-	-			23.6	223.6	174.8		-	39.8	150.3	128.8	131.3
CommonStockPayments_A Common Stock Payments Ann.	-	-	-0.1	-0.4	-	-	-	-	-	-	-	-	-
dividend_1Y_actual Dividend 1year	-	-
DividendPerShare_A Dividend Per Share Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
NetOtherFinancingCharges_A Net Other Financing Charges Ann.	-	-	-	-	-	-	-	-	-	-	-	15.2	3.9
CashAndCashEquivalentEndOfYear_A Cash Plus Cash Eqv. End Of Year Ann.	-24.4%	0.7%	308.4	472.3	621	712.6	580.5	298.1	378.4	431.7	421.7	391	370.6
NetIncDecInCashAndCashEquivalents_A Net Increase In Cash Plus Cash Eqv.s Ann.	-	-	-163.9	-148.8	-91.6	132.2	282.4	-80.3	-53.3	10	30.7	20.4	77
CashAndCashEquivalentBeginOfYear_A Cash Plus Cash Eqv. Begin Of Year Ann.	-6.6%	4.5%	472.3	621	712.6	580.5	298.1	378.4	431.7	421.7	391	370.6	293.6
IncomeTaxPaidSupplementalData_A Income Tax Paid Supplemental Data Ann.	-30.7%	-8.5%	0.9	3.2	1.6	2.7	0.6	1.4	1.6	-	0.3	0.6	0.4
InterestPaidSupplementalData_A Interest Paid Supplemental Data Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
CapitalExpenditure_A Capex Ann.	-	-	-0.1	-0.3	-2.8	-0.5	-0.6	-0.2	-0.6	-1.8	-3.6	-16.6	-1.4
IssuanceOfCapitalStock_A Issuance Of Capital Stock Ann.	-	-			23.6	223.6	174.8		-	39.8	150.3	128.8	131.3
IssuanceOfDebt_A Issuance Of Debt Ann.	-	-	-	-	-	-	-	-	-	-	-	-	-
RepaymentOfDebt_A Repayment Of Debt Ann.	-	-	-	-	-	-	-		-	-4.4	-2.8	-0.2	-
RepurchaseOfCapitalStock_A Repurchase Of Capital Stock Ann.	-	-	-0.1	-0.4	-	-	-	-	-	-	-	-	-
FreeCashFlow_A Free Cash Flow Ann.	-	-	-163.7	-150.4	-136.7	-109.3	92	-80.6	-53.5	-30	-134.8	-133.9	-63.8

*All financials are in USD Million and price data in USD

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25.08% Fall from 52W High

Prothena Corporation plc quarterly and annual earnings report: results, revenue, profit, P&L, balance sheet, cash flow, financial ratios, revenue mix, peer comparison, and financial documents

Prothena Corporation plc - Forecaster

Forecaster Analyst Estimates for Prothena Corporation plc share price target, revenues, EPS, net income and more

Prothena Corporation plc - Earnings Report - Quarterly Results

Prothena Corporation plc quarterly results: revenue, profit, and P&L – 13 quarter history

Quarterly Revenue Prothena Corporation plc Jun-2026 Quarterly Revenue is $1 Million which is growth of -77.1% YoY.

Quarterly Net Profit Prothena Corporation plc Jun-2026 Quarterly Net Profit is $-19 Million which is growth of 85.2% YoY.

Prothena Corporation plc - Competitors/Peers

Prothena Corporation plc competitor comparison and performance snapshot within industry

Prothena Corporation plc - Earnings Report - Annual Results

Prothena Corporation plc annual results: revenue, profit, P&L, and margins as of Dec 2025 – 11 year history

Annual Revenue Prothena Corporation plc Dec-2025 Annual Revenue is $10 Million which is growth of -92.8% YoY.

Annual Net Profit Prothena Corporation plc Dec-2025 Annual Net Profit is $-244 Million which is growth of -99.6% YoY.

Prothena Corporation plc - Balance Sheet

Prothena Corporation plc balance sheet as of Dec 2025: assets, liabilities, reserves, and borrowings – 11 year history

Total Shareholders Fund Prothena Corporation plc Dec-2025 Total Shareholders Fund is $280 Million which is growth of -42.4% YoY.

Total Assets Prothena Corporation plc Dec-2025 Total Assets is $327 Million which is growth of -40.3% YoY.

Prothena Corporation plc - Ratios

Prothena Corporation plc ROE, ROCE, book value, and debt-to-equity ratio as of Dec 2025 – 11 year history

Book Value Per Share Prothena Corporation plc Book Value Per Share is $6 which is growth of -7.2% YoY.

ROE Prothena Corporation plc ROE is 0% which is growth of 0% YoY.

Prothena Corporation plc - Cash Flow

Prothena Corporation plc cash flow: net, operating, investing, and financing flows as of Dec 2025 – 11 year history

Cash From Operating Activity Prothena Corporation plc Dec-2025 Cash From Operating Activity is $-164 Million which is growth of -9.0% YoY.

Net Cash Flow Prothena Corporation plc Dec-2025 Net Cash Flow is $-164 Million which is growth of -10.1% YoY.