Krish S. Krishnan's most recent trade in Krystal Biotech Inc was a trade of 3,981 Common Stock done at an average price of $357.6 . Disclosure was reported to the exchange on Sept. 4, 2026.
| Stock | Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|---|
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 357.57 per share. | 04 Sep 2026 | 3,981 | 1,362,716 (7%) | 0% | 357.6 | 1,423,501 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 359.39 per share. | 04 Sep 2026 | 3,357 | 1,356,216 (7%) | 0% | 359.4 | 1,206,459 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 356.37 per share. | 04 Sep 2026 | 3,297 | 1,366,697 (7%) | 0% | 356.4 | 1,174,948 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 358.42 per share. | 04 Sep 2026 | 3,143 | 1,359,573 (7%) | 0% | 358.4 | 1,126,508 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 360.46 per share. | 04 Sep 2026 | 2,266 | 1,353,950 (7%) | 0% | 360.5 | 816,809 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 355.57 per share. | 04 Sep 2026 | 2,029 | 1,369,994 (7%) | 0% | 355.6 | 721,455 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 362.65 per share. | 04 Sep 2026 | 2,010 | 1,350,726 (7%) | 0% | 362.7 | 728,927 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 364.48 per share. | 04 Sep 2026 | 1,358 | 1,348,795 (7%) | 0% | 364.5 | 494,963 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 361.61 per share. | 04 Sep 2026 | 1,214 | 1,352,736 (7%) | 0% | 361.6 | 438,993 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 365.42 per share. | 04 Sep 2026 | 847 | 1,347,948 (7%) | 0% | 365.4 | 309,508 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 363.34 per share. | 04 Sep 2026 | 573 | 1,350,153 (7%) | 0% | 363.3 | 208,195 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 354.54 per share. | 04 Sep 2026 | 520 | 1,372,023 (7%) | 0% | 354.5 | 184,361 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 366.56 per share. | 04 Sep 2026 | 405 | 1,347,543 (7%) | 0% | 366.6 | 148,455 | Common Stock |
| Community Health Systems Inc | Dr. K. Ranga Krishnan, M.B.B.S. | Director | 30 Jun 2026 | 13,930 | 55,722 | - | - | Stock Units (SU) | ||
| Community Health Systems Inc | Dr. K. Ranga Krishnan, M.B.B.S. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jun 2026 | 13,930 | 170,023 (0%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 307.68 per share. | 04 Jun 2026 | 11,461 | 1,461,523 (8%) | 0% | 307.7 | 3,526,293 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 308.47 per share. | 04 Jun 2026 | 4,830 | 1,456,693 (8%) | 0% | 308.5 | 1,489,899 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 309.49 per share. | 04 Jun 2026 | 2,784 | 1,453,909 (8%) | 0% | 309.5 | 861,620 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 310.43 per share. | 04 Jun 2026 | 2,652 | 1,451,257 (8%) | 0% | 310.4 | 823,258 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 311.36 per share. | 04 Jun 2026 | 964 | 1,450,293 (8%) | 0% | 311.4 | 300,149 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 302.24 per share. | 04 Jun 2026 | 640 | 1,474,293 (8%) | 0% | 302.2 | 193,431 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 306.33 per share. | 04 Jun 2026 | 589 | 1,472,984 (8%) | 0% | 306.3 | 180,429 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 304.81 per share. | 04 Jun 2026 | 544 | 1,473,573 (8%) | 0% | 304.8 | 165,817 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 300.75 per share. | 04 Jun 2026 | 320 | 1,474,933 (8%) | 0% | 300.8 | 96,240 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 303.17 per share. | 04 Jun 2026 | 176 | 1,474,117 (8%) | 0% | 303.2 | 53,358 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 312.22 per share. | 04 Jun 2026 | 40 | 1,450,253 (8%) | 0% | 312.2 | 12,489 | Common Stock |
| Community Health Systems Inc | Dr. K. Ranga Krishnan, M.B.B.S. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Apr 2026 | 46,950 | 156,093 (0%) | 0% | 0 | Common Stock | |
| Community Health Systems Inc | Dr. K. Ranga Krishnan, M.B.B.S. | Director | 22 Apr 2026 | 46,950 | 228,321 | - | - | Restricted Stock Units | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 264.85 per share. | 04 Mar 2026 | 8,798 | 1,478,612 (8%) | 0% | 264.9 | 2,330,151 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 264.85 per share. | 04 Mar 2026 | 8,798 | 1,478,612 (8%) | 0% | 264.9 | 2,330,151 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 260.49 per share. | 04 Mar 2026 | 3,128 | 1,494,795 (8%) | 0% | 260.5 | 814,802 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 260.49 per share. | 04 Mar 2026 | 3,128 | 1,494,795 (8%) | 0% | 260.5 | 814,802 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 261.41 per share. | 04 Mar 2026 | 2,962 | 1,491,833 (8%) | 0% | 261.4 | 774,289 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 261.41 per share. | 04 Mar 2026 | 2,962 | 1,491,833 (8%) | 0% | 261.4 | 774,289 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 265.59 per share. | 04 Mar 2026 | 2,439 | 1,476,173 (8%) | 0% | 265.6 | 647,773 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 265.59 per share. | 04 Mar 2026 | 2,439 | 1,476,173 (8%) | 0% | 265.6 | 647,773 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 262.44 per share. | 04 Mar 2026 | 2,380 | 1,489,453 (8%) | 0% | 262.4 | 624,619 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 262.44 per share. | 04 Mar 2026 | 2,380 | 1,489,453 (8%) | 0% | 262.4 | 624,619 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 263.70 per share. | 04 Mar 2026 | 2,043 | 1,487,410 (8%) | 0% | 263.7 | 538,741 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 263.70 per share. | 04 Mar 2026 | 2,043 | 1,487,410 (8%) | 0% | 263.7 | 538,741 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 259.87 per share. | 04 Mar 2026 | 1,377 | 1,497,923 (8%) | 0% | 259.9 | 357,838 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 259.87 per share. | 04 Mar 2026 | 1,377 | 1,497,923 (8%) | 0% | 259.9 | 357,838 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 266.56 per share. | 04 Mar 2026 | 920 | 1,475,253 (8%) | 0% | 266.6 | 245,231 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 266.56 per share. | 04 Mar 2026 | 920 | 1,475,253 (8%) | 0% | 266.6 | 245,231 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 257.31 per share. | 04 Mar 2026 | 483 | 1,499,770 (8%) | 0% | 257.3 | 124,282 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 257.31 per share. | 04 Mar 2026 | 483 | 1,499,770 (8%) | 0% | 257.3 | 124,282 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 258.38 per share. | 04 Mar 2026 | 470 | 1,499,300 (8%) | 0% | 258.4 | 121,438 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 258.38 per share. | 04 Mar 2026 | 470 | 1,499,300 (8%) | 0% | 258.4 | 121,438 | - |
| Community Health Systems Inc | Dr. K. Ranga Krishnan, M.B.B.S. | Director | 01 Mar 2026 | 52,023 | 275,271 | - | - | Restricted Stock Units | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | 27 Feb 2026 | 45,249 | 45,249 | - | - | Stock Option (Right to Buy) | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | 27 Feb 2026 | 26,250 | 0 | - | - | Performance Stock Units | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 26,250 | 1,509,075 (8%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 26,250 | 1,509,075 (8%) | 0% | 0 | - | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 22,500 | 1,436,211 (8%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 22,500 | 1,436,211 (8%) | 0% | 0 | - | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | 27 Feb 2026 | 18,140 | 18,140 | - | - | Restricted Stock Units | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 11,942 | 1,497,133 (8%) | 0% | 275.6 | 3,291,693 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 11,942 | 1,497,133 (8%) | 0% | 275.6 | 3,291,693 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 10,236 | 1,425,975 (8%) | 0% | 275.6 | 2,821,451 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 10,236 | 1,425,975 (8%) | 0% | 275.6 | 2,821,451 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | 27 Feb 2026 | 8,750 | 17,500 | - | - | Restricted Stock Units | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 8,750 | 1,486,806 (8%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 8,750 | 1,486,806 (8%) | 0% | 0 | - | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | 27 Feb 2026 | 5,725 | 17,175 | - | - | Restricted Stock Units | ||
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 5,725 | 1,502,858 (8%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 5,725 | 1,502,858 (8%) | 0% | 0 | - | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 4,000 | 1,429,975 (8%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2026 | 4,000 | 1,429,975 (8%) | 0% | 0 | - | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 3,981 | 1,482,825 (8%) | 0% | 275.6 | 1,097,323 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 3,981 | 1,482,825 (8%) | 0% | 275.6 | 1,097,323 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 2,605 | 1,500,253 (8%) | 0% | 275.6 | 718,042 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 2,605 | 1,500,253 (8%) | 0% | 275.6 | 718,042 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 1,820 | 1,428,155 (8%) | 0% | 275.6 | 501,665 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Payment of exercise price or tax liability using portion of securities received from the company at price $ 275.64 per share. | 27 Feb 2026 | 1,820 | 1,428,155 (8%) | 0% | 275.6 | 501,665 | - |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 221.78 per share. | 04 Dec 2025 | 10,505 | 1,483,756 (8%) | 0% | 221.8 | 2,329,772 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 221.82 per share. | 04 Dec 2025 | 10,461 | 1,413,911 (8%) | 0% | 221.8 | 2,320,471 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 219.55 per share. | 04 Dec 2025 | 5,693 | 1,496,886 (8%) | 0% | 219.6 | 1,249,917 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 219.68 per share. | 04 Dec 2025 | 5,419 | 1,426,999 (8%) | 0% | 219.7 | 1,190,423 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 04 Dec 2025 | 5,000 | 1,478,056 (8%) | 0% | 0 | Common Stock | |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 218.83 per share. | 04 Dec 2025 | 3,593 | 1,432,418 (8%) | 0% | 218.8 | 786,245 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 220.52 per share. | 04 Dec 2025 | 2,627 | 1,424,372 (8%) | 0% | 220.5 | 579,301 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 220.34 per share. | 04 Dec 2025 | 2,625 | 1,494,261 (8%) | 0% | 220.3 | 578,395 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 218.72 per share. | 04 Dec 2025 | 2,577 | 1,502,579 (8%) | 0% | 218.7 | 563,638 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 217.04 per share. | 04 Dec 2025 | 1,600 | 1,505,156 (8%) | 0% | 217.0 | 347,272 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 216.97 per share. | 04 Dec 2025 | 1,400 | 1,436,011 (8%) | 0% | 217.0 | 303,754 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 214.28 per share. | 04 Dec 2025 | 956 | 1,507,100 (8%) | 0% | 214.3 | 204,851 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 214.25 per share. | 04 Dec 2025 | 700 | 1,438,011 (8%) | 0% | 214.3 | 149,975 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 222.20 per share. | 04 Dec 2025 | 700 | 1,483,056 (8%) | 0% | 222.2 | 155,539 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 215.49 per share. | 04 Dec 2025 | 600 | 1,437,411 (8%) | 0% | 215.5 | 129,296 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 215.48 per share. | 04 Dec 2025 | 344 | 1,506,756 (8%) | 0% | 215.5 | 74,126 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 222.38 per share. | 04 Dec 2025 | 200 | 1,413,711 (8%) | 0% | 222.4 | 44,475 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.30 per share. | 14 Jul 2025 | 13,400 | 1,512,529 (8%) | 0% | 150.3 | 2,014,015 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.29 per share. | 14 Jul 2025 | 13,335 | 1,443,376 (8%) | 0% | 150.3 | 2,004,125 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.68 per share. | 14 Jul 2025 | 2,236 | 1,441,040 (8%) | 0% | 150.7 | 336,929 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.68 per share. | 14 Jul 2025 | 2,184 | 1,510,345 (8%) | 0% | 150.7 | 329,089 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.00 per share. | 14 Jul 2025 | 1,529 | 1,438,711 (8%) | 0% | 150 | 229,350 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.00 per share. | 14 Jul 2025 | 1,389 | 1,508,056 (8%) | 0% | 150 | 208,350 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 151.79 per share. | 14 Jul 2025 | 900 | 1,509,445 (8%) | 0% | 151.8 | 136,611 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 151.79 per share. | 14 Jul 2025 | 800 | 1,440,240 (8%) | 0% | 151.8 | 121,432 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 151.00 per share. | 14 Jul 2025 | 100 | 1,443,276 (8%) | 0% | 151 | 15,100 | Common Stock |
| Krystal Biotech Inc | Mr. Krish S. Krishnan | Director, President and CEO, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 150.22 per share. | 09 Jul 2025 | 6,627 | 1,526,229 (8%) | 0% | 150.2 | 995,497 | Common Stock |