Manke Isaac's most recent trade in Q32 Bio Inc. was a trade of 53,521 Stock Option (Right to Buy) done . Disclosure was reported to the exchange on Oct. 23, 2025.
| Stock | Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|---|
| Q32 Bio Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Oct 2025 | 53,521 | 53,521 | - | - | Stock Option (Right to Buy) | |
| OnKure Therapeutics Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2025 | 5,545 | 15,325 | - | 0 | Class A Common Stock | |
| OnKure Therapeutics Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2025 | 6,311 | 9,780 | - | 0 | Class A Common Stock | |
| OnKure Therapeutics Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 May 2025 | 7,650 | 7,650 | - | - | Stock Option (right to buy) | |
| OnKure Therapeutics Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2025 | 3,469 | 3,469 | - | 0 | Class A Common Stock | |
| Q32 Bio Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 19,008 | 19,008 | - | - | Stock Option (Right to Buy) | |
| Q32 Bio Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 19,008 | 19,008 | - | - | Stock Option (Right to Buy) | |
| Q32 Bio Inc | Isaac Manke | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 15 Jan 2025 | 19,008 | 0 | - | - | Stock Option (Right to Buy) | |
| Q32 Bio Inc | Isaac Manke | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 15 Jan 2025 | 12,767 | 0 | - | - | Stock Option (Right to Buy) | |
| Q32 Bio Inc | Manke Isaac | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 12,767 | 12,767 | - | - | Stock Option (Right to Buy) | |
| Q32 Bio Inc | Isaac Manke | Director | Sale or transfer of securities back to the company at price $ 0.00 per share. | 15 Jan 2025 | 2,627 | 0 | - | - | Stock Option (Right to Buy) | |
| Q32 Bio Inc | Manke Isaac | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 2,627 | 2,627 | - | - | Stock Option (Right to Buy) | |
| OnKure Therapeutics Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 Oct 2024 | 15,300 | 15,300 | - | - | Stock Option (right to buy) | |
| Q32 Bio Inc | Isaac Manke | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Mar 2024 | 12,767 | 12,767 | - | - | Stock Option (Right to Buy) |