XNAS 05 Mar, 2026 4:30 PM (EST)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Gregg Russo | Chief HR Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Feb 2026 | 687 | 687 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gregg Russo | Chief HR Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 17 Feb 2026 | 211 | 476 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gregg Russo | Chief HR Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Feb 2026 | 687 | 71,786 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jan 2026 | 42,105 | 281,843 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 05 Jan 2026 | 10,577 | 271,266 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jan 2026 | 42,105 | 2,618,539 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 178,163 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 383,314 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 178,163 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 498,773 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 29 Dec 2025 | 6,786 | 4,171,559 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 26,334 | 1,851,948 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 26,334 | 4,178,345 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 14,000 | 1,093,803 (1%) | 0% | - | Common stock, par value $0.001 per share | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 14,000 | 1,471,649 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 2,660,644 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 29 Dec 2025 | 524 | 239,738 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 240,262 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 6,667 | 245,124 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 29 Dec 2025 | 2,623 | 242,501 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 6,667 | 956,142 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 8,667 | 1,036,846 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 8,667 | 18,176 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 29 Dec 2025 | 3,839 | 14,337 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 127,163 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 1,334 | 3,694 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 29 Dec 2025 | 2,369 | 54,804 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 6,667 | 798,437 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Dec 2025 | 6,667 | 57,173 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Molly Harper | Director | Sale of securities on an exchange or to another person at price $ 23.73 per share. | 12 Dec 2025 | 4,473 | 9,106 (0%) | 0% | 23.7 | 106,162 | Common stock, par value $0.001 per share |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2025 | 20,000 | 128,497 | - | - | Options to purchase common stock | |
| Molly Harper | Director | Sale of securities on an exchange or to another person at price $ 23.06 per share. | 12 Dec 2025 | 6,746 | 2,360 (0%) | 0% | 23.1 | 155,563 | Common stock, par value $0.001 per share |
| Molly Harper | Director | Sale of securities on an exchange or to another person at price $ 23.20 per share. | 12 Dec 2025 | 15,527 | 13,579 (0%) | 0% | 23.2 | 360,195 | Common stock, par value $0.001 per share |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.78 per share. | 12 Dec 2025 | 20,000 | 29,106 (0%) | 0% | 5.8 | 115,600 | Common stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 381,980 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 179,497 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 179,497 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 497,439 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 3,534 | 4,152,011 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 3,534 | 1,878,282 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 11,873 | 1,485,649 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 11,873 | 1,079,803 (1%) | 0% | - | Common stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 08 Dec 2025 | 2,780 | 238,457 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 7,067 | 962,809 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 7,067 | 241,237 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 08 Dec 2025 | 2,492 | 9,509 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 8,039 | 12,001 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 8,039 | 1,045,513 | - | - | Restricted Stock Units | |
| Tamar Thompson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 3,773 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Tamar Thompson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 119,663 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 148,497 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 1,413 | 9,106 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 08 Dec 2025 | 1,669 | 50,506 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 6,855 | 805,104 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2025 | 6,855 | 52,175 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Dec 2025 | 45,000 | 4,148,477 (4%) | 0% | 0 | Common stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Dec 2025 | 45,000 | 4,193,477 (4%) | 0% | 0 | Common stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Gift of securities by or to the insider at price $ 0.00 per share. | 01 Dec 2025 | 45,000 | 4,328,477 (4%) | 0% | 0 | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 23.33 per share. | 26 Nov 2025 | 10,983 | 3,962 (0%) | 0% | 23.3 | 256,244 | Common Stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.21 per share. | 26 Nov 2025 | 10,983 | 14,945 (0%) | 0% | 4.2 | 46,238 | Common Stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Nov 2025 | 10,983 | 1,053,552 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 180,910 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 380,567 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| David S. Tierney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 18,115 | 176,389 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 5,468 | 181,857 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 496,026 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 18,115 | 176,389 | - | - | Options to purchase common stock | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 180,910 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 5,468 | 181,857 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 34,921 | 1,873,051 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 1,775 | 1,881,816 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 1,775 | 4,283,477 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 10,540 | 1,883,591 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 8,267 | 1,497,522 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 47,826 | 1,489,255 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 158,454 | 1,457,963 | - | - | Options to purchase common stock | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 8,267 | 1,067,930 (1%) | 0% | - | Common stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 20,006 | 246,800 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 20 Nov 2025 | 7,872 | 238,928 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 381,948 | 2,546,695 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 115,283 | 2,681,984 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 20,006 | 2,661,978 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 5,161 | 236,200 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 98,652 | 945,161 | - | - | Options to purchase common stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 29,776 | 975,037 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 5,161 | 969,876 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 20 Nov 2025 | 2,030 | 234,170 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 32,257 | 1,070,138 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 5,603 | 1,064,535 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 20 Nov 2025 | 1,641 | 3,962 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 5,603 | 5,603 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 106,873 | 1,037,881 | - | - | Options to purchase common stock | |
| Tamar Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 18,115 | 116,555 | - | - | Options to purchase common stock | |
| Tamar Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 5,468 | 122,023 | - | - | Restricted Stock Units | |
| Tamar Thompson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 121,076 | - | - | Restricted Stock Units | |
| Tamar Thompson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 2,360 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 149,910 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 5,468 | 150,857 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 18,115 | 145,389 | - | - | Options to purchase common stock | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 947 | 7,693 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 32,257 | 817,562 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 20 Nov 2025 | 1,364 | 45,320 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 106,873 | 785,305 | - | - | Options to purchase common stock | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 5,603 | 46,684 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2025 | 5,603 | 811,959 | - | - | Restricted Stock Units | |
| Daniel Curran | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 18,115 | 58,115 | - | - | Options to purchase common stock | |
| Daniel Curran | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 5,468 | 63,583 | - | - | Restricted Stock Units | |
| Gregg Russo | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 6,197 | 72,473 | - | - | Restricted Stock Units | |
| Gregg Russo | Chief HR Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Nov 2025 | 20,531 | 66,276 | - | - | Options to purchase common stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 22.70 per share. | 12 Nov 2025 | 40,000 | 231,039 (0%) | 0% | 22.7 | 908,000 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Sep 2025 | 112,475 | 846,609 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 08 Sep 2025 | 112,475 | 301,039 (0%) | 0% | 2.2 | 251,944 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 20.30 per share. | 08 Sep 2025 | 30,000 | 271,039 (0%) | 0% | 20.3 | 609,000 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Sep 2025 | 20,000 | 989,084 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 19.52 per share. | 03 Sep 2025 | 30,000 | 188,564 (0%) | 0% | 19.5 | 585,600 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 03 Sep 2025 | 30,000 | 218,564 (0%) | 0% | 2.2 | 67,200 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 20.08 per share. | 03 Sep 2025 | 20,000 | 188,564 (0%) | 0% | 20.1 | 401,600 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 03 Sep 2025 | 20,000 | 208,564 (0%) | 0% | 2.2 | 44,800 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Sep 2025 | 30,000 | 959,084 | - | - | Options to Purchase Common Stock | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 27 Aug 2025 | 50,000 | 405,620 (0%) | 0% | 2.2 | 112,000 | Common Stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Aug 2025 | 50,000 | 158,274 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Sale of securities on an exchange or to another person at price $ 20.20 per share. | 27 Aug 2025 | 26,000 | 379,620 (0%) | 0% | 20.2 | 525,200 | Common Stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 26 Aug 2025 | 110,000 | 1,059,663 (1%) | 0% | 2.2 | 246,400 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.28 per share. | 26 Aug 2025 | 115,000 | 949,663 (0%) | 0% | 20.3 | 2,332,200 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 26 Aug 2025 | 115,000 | 1,064,663 (1%) | 0% | 2.2 | 257,600 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2025 | 110,000 | 1,299,509 | - | - | Options to purchase common stock | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2025 | 115,000 | 1,409,509 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.62 per share. | 26 Aug 2025 | 22,970 | 226,794 (0%) | 0% | 20.6 | 473,641 | Common stock, par value $0.001 per share |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Aug 2025 | 50,000 | 2,184,753 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 26 Aug 2025 | 50,000 | 249,764 (0%) | 0% | 2.2 | 112,000 | Common stock, par value $0.001 per share |
| Preethi Sundaram | Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 26.41 per share. | 10 Jun 2025 | 2,324 | 42,681 (0%) | 0% | 26.4 | 61,377 | Common Stock, par value $0.001 per share |
| Preethi Sundaram | Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 26.42 per share. | 10 Jun 2025 | 1,600 | 41,081 (0%) | 0% | 26.4 | 42,272 | Common Stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 25.94 per share. | 06 Jun 2025 | 28,252 | 4,453,450 (4%) | 0% | 25.9 | 732,998 | Common Stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 26.11 per share. | 06 Jun 2025 | 171,748 | 4,281,702 (4%) | 0% | 26.1 | 4,484,340 | Common Stock, par value $0.001 per share |
| Richard J. Daly | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 24.86 per share. | 30 May 2025 | 70,000 | 199,764 (0%) | 0% | 24.9 | 1,740,200 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2025 | 200,000 | 590,282 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 23.68 per share. | 13 May 2025 | 200,000 | 68,873 (0%) | 0% | 23.7 | 4,736,000 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.42 per share. | 13 May 2025 | 200,000 | 268,873 (0%) | 0% | 3.4 | 684,000 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 23.63 per share. | 13 May 2025 | 44,000 | 68,873 (0%) | 0% | 23.6 | 1,039,720 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.64 per share. | 13 May 2025 | 44,000 | 112,873 (0%) | 0% | 4.6 | 204,160 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 May 2025 | 44,000 | 546,282 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 21.67 per share. | 05 Mar 2025 | 180,096 | 68,873 (0%) | 0% | 21.7 | 3,902,680 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 22.09 per share. | 05 Mar 2025 | 44,904 | 68,873 (0%) | 0% | 22.1 | 991,929 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 05 Mar 2025 | 44,904 | 113,777 (0%) | 0% | 2.2 | 100,585 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 05 Mar 2025 | 180,096 | 248,969 (0%) | 0% | 2.2 | 403,415 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 44,904 | 970,378 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Mar 2025 | 180,096 | 790,282 | - | - | Options to purchase common stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 23.23 per share. | 03 Mar 2025 | 9,720 | 188,564 (0%) | 0% | 23.2 | 225,796 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 03 Mar 2025 | 9,270 | 197,834 (0%) | 0% | 2.2 | 20,765 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 53,255 | 1,009,084 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Mar 2025 | 9,270 | 1,062,339 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 22.93 per share. | 03 Mar 2025 | 53,255 | 188,564 (0%) | 0% | 22.9 | 1,221,137 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 03 Mar 2025 | 53,255 | 241,819 (0%) | 0% | 2.2 | 119,291 | Common Stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 22.89 per share. | 03 Mar 2025 | 30,423 | 0 (0%) | 0% | 22.9 | 696,382 | Common stock, par value $0.001 per share |
| Charles B. O'Keeffe | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 732,470 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Charles B. O'Keeffe | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 208,274 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 355,620 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 208,274 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 495,079 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 158,274 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 13,667 | 949,663 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 13,667 | 1,524,509 | - | - | Restricted Stock Units | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 10,000 | 71,308 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 14 Feb 2025 | 2,435 | 68,873 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 10,000 | 1,015,282 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 271,338 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 14 Feb 2025 | 1,574 | 269,764 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 2,234,753 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 14 Feb 2025 | 2,353 | 188,564 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 9,667 | 1,071,609 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 9,667 | 190,917 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 14 Feb 2025 | 3,125 | 30,423 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 10,667 | 33,548 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 10,667 | 931,008 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 127,274 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 4,000 | 6,746 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 16,667 | 678,432 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Feb 2025 | 16,667 | 50,970 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 14 Feb 2025 | 5,965 | 45,005 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 08 Jan 2025 | 50,000 | 491,079 (0%) | 0% | 2.2 | 112,000 | Common Stock, par value $0.001 per share |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Jan 2025 | 50,000 | 162,274 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 42,105 | 277,938 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 02 Jan 2025 | 10,600 | 267,338 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 42,105 | 2,238,753 | - | - | Restricted Stock Units | |
| Charles B. O'Keeffe | Director | 27 Dec 2024 | 1,333 | 728,470 (0%) | 0% | - | Common Stock, par value $0.001 per share | ||
| Charles B. O'Keeffe | Director | 27 Dec 2024 | 1,333 | 212,274 | - | - | Restricted Stock Units | ||
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 212,274 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 351,620 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 441,079 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 212,274 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 14,000 | 935,996 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 14,000 | 1,538,176 | - | - | Restricted Stock Units | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 9,000 | 1,025,282 | - | - | Restricted Stock Units | |
| Gary Ingenito | Chief Med. & Reg. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2024 | 3,541 | 61,308 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 9,000 | 64,849 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 2,280,858 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2024 | 324 | 235,833 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 236,157 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 6,667 | 1,081,276 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2024 | 1,941 | 181,250 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 6,667 | 183,191 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 131,274 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 1,333 | 2,746 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 6,667 | 695,099 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 6,667 | 36,648 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2024 | 2,345 | 34,303 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 8,667 | 941,675 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2024 | 8,667 | 26,720 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2024 | 3,839 | 22,881 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 13 Dec 2024 | 235,000 | 921,996 (0%) | 0% | 4.0 | 942,350 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Dec 2024 | 235,000 | 1,552,176 | - | - | Options to purchase common stock | |
| Charles B. O'Keeffe | Director | 09 Dec 2024 | 1,413 | 253,607 | - | - | Restricted Stock Units | ||
| Charles B. O'Keeffe | Director | 09 Dec 2024 | 1,413 | 687,137 (0%) | 0% | - | Common Stock, par value $0.001 per share | ||
| Charles B. O'Keeffe | Director | 09 Dec 2024 | 40,000 | 213,607 | - | - | Options to purchase common stock | ||
| Charles B. O'Keeffe | Director | 09 Dec 2024 | 40,000 | 727,137 (0%) | 0% | 4.0 | 160,400 | Common Stock, par value $0.001 per share | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 213,607 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 350,287 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 439,746 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 213,607 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 3,533 | 4,481,702 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 3,533 | 1,838,130 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 11,872 | 686,996 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 50,000 | 1,787,176 | - | - | Options to purchase common stock | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 11,872 | 1,837,176 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Sale of securities on an exchange or to another person at price $ 21.93 per share. | 09 Dec 2024 | 50,000 | 686,996 (0%) | 0% | 21.9 | 1,096,350 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 09 Dec 2024 | 50,000 | 736,996 (0%) | 0% | 4.0 | 200,500 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 09 Dec 2024 | 2,891 | 55,849 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 7,349 | 58,740 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 7,349 | 1,034,282 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 09 Dec 2024 | 1,720 | 176,524 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 7,067 | 178,244 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 7,067 | 1,087,943 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 09 Dec 2024 | 2,355 | 18,053 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 8,039 | 20,408 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 8,039 | 950,342 | - | - | Restricted Stock Units | |
| Tamar Thompson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 1,413 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Tamar Thompson | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 98,440 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 132,607 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 1,413 | 1,413 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 09 Dec 2024 | 2,415 | 29,981 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 6,855 | 701,766 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Dec 2024 | 6,855 | 32,396 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Nov 2024 | 12,000 | 1,041,631 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 22.74 per share. | 27 Nov 2024 | 8,631 | 54,760 (0%) | 0% | 22.7 | 196,269 | Common stock, par value $0.001 per share |
| Ingenito Gary | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 22.67 per share. | 27 Nov 2024 | 3,369 | 51,391 (0%) | 0% | 22.7 | 76,385 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 27 Nov 2024 | 12,000 | 63,391 (0%) | 0% | 4.0 | 48,120 | Common stock, par value $0.001 per share |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.78 per share. | 27 Nov 2024 | 17,500 | 17,500 (0%) | 0% | 5.8 | 101,150 | Common stock, par value $0.001 per share |
| Harper Molly | Director | Sale of securities on an exchange or to another person at price $ 22.00 per share. | 27 Nov 2024 | 17,500 | 0 (0%) | 0% | 22 | 385,000 | Common stock, par value $0.001 per share |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Nov 2024 | 17,500 | 134,020 | - | - | Options to purchase common stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 26 Nov 2024 | 50,244 | 174,677 (0%) | 0% | 4.0 | 201,478 | Common Stock, par value $0.001 per share |
| Elsbernd Brian | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 26 Nov 2024 | 9,756 | 175,133 (0%) | 0% | 4.0 | 39,122 | Common Stock, par value $0.001 per share |
| Elsbernd Brian | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Nov 2024 | 50,244 | 1,104,766 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 21.58 per share. | 26 Nov 2024 | 3,956 | 171,177 (0%) | 0% | 21.6 | 85,359 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Nov 2024 | 9,756 | 1,095,010 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 21.65 per share. | 26 Nov 2024 | 9,300 | 165,377 (0%) | 0% | 21.7 | 201,345 | Common Stock, par value $0.001 per share |
| Charles B. O'Keeffe | Director | 21 Nov 2024 | 23,248 | 252,179 | - | - | Options to purchase common stock | ||
| Charles B. O'Keeffe | Director | 21 Nov 2024 | 2,841 | 255,020 | - | - | Restricted stock units | ||
| David S. Tierney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 2,841 | 215,020 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 23,248 | 212,179 | - | - | Options to purchase common stock | |
| Donald A. Denkhaus | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 23,248 | 212,179 | - | - | Options to purchase common stock | |
| Donald A. Denkhaus | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 2,841 | 215,020 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 5,327 | 1,841,663 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 43,591 | 1,836,336 | - | - | Options to purchase common stock | |
| Steven R. Miller | Chief Op. & Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 24,801 | 1,849,048 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 202,958 | 1,824,247 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 125,696 | 1,038,271 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 15,360 | 1,053,631 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 60,019 | 2,282,191 | - | - | Restricted Stock Units | |
| Richard J. Daly | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 491,160 | 2,222,172 | - | - | Options to purchase common stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 15,483 | 1,155,010 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 126,704 | 1,139,527 | - | - | Options to purchase common stock | |
| Carmen Jeffrey Del | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 137,553 | 941,572 | - | - | Options to purchase common stock | |
| Carmen Jeffrey Del | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 16,809 | 958,381 | - | - | Restricted Stock Units | |
| Tamar Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 23,248 | 97,012 | - | - | Options to purchase common stock | |
| Tamar Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 2,841 | 99,853 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 2,841 | 151,520 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 23,248 | 148,679 | - | - | Options to purchase common stock | |
| Preethi Sundaram | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 16,809 | 708,621 | - | - | Options to purchase common stock | |
| Preethi Sundaram | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Nov 2024 | 137,553 | 691,812 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 20 Nov 2024 | 38,000 | 89,391 (0%) | 0% | 4.0 | 152,380 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Nov 2024 | 38,000 | 912,575 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 21.20 per share. | 20 Nov 2024 | 38,000 | 51,391 (0%) | 0% | 21.2 | 805,562 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.54 per share. | 19 Nov 2024 | 98,345 | 4,576,514 (4%) | 0% | 3.5 | 348,141 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2024 | 72,500 | 1,792,745 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 19 Nov 2024 | 98,345 | 1,865,245 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 21.29 per share. | 19 Nov 2024 | 72,500 | 4,478,169 (4%) | 0% | 21.3 | 1,543,525 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.54 per share. | 19 Nov 2024 | 72,500 | 4,550,669 (4%) | 0% | 3.5 | 256,650 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 21.19 per share. | 19 Nov 2024 | 98,345 | 4,478,169 (4%) | 0% | 21.2 | 2,083,734 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 21.75 per share. | 13 Nov 2024 | 44,655 | 4,478,169 (4%) | 0% | 21.8 | 971,336 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.54 per share. | 13 Nov 2024 | 44,655 | 4,522,824 (4%) | 0% | 3.5 | 158,079 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 22.98 per share. | 13 Nov 2024 | 92,500 | 4,478,169 (4%) | 0% | 23.0 | 2,125,465 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.54 per share. | 13 Nov 2024 | 92,500 | 4,570,669 (4%) | 0% | 3.5 | 327,450 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Nov 2024 | 44,655 | 1,963,590 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Nov 2024 | 92,500 | 2,008,245 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 11 Nov 2024 | 230,000 | 4,708,169 (4%) | 0% | 4.0 | 922,300 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Nov 2024 | 70,000 | 2,292,745 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Nov 2024 | 192,000 | 2,100,745 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Nov 2024 | 230,000 | 2,362,745 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 23.20 per share. | 11 Nov 2024 | 192,000 | 4,478,169 (4%) | 0% | 23.2 | 4,454,592 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 3.54 per share. | 11 Nov 2024 | 192,000 | 4,670,169 (4%) | 0% | 3.5 | 679,680 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 23.42 per share. | 11 Nov 2024 | 70,000 | 4,478,169 (4%) | 0% | 23.4 | 1,639,470 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 11 Nov 2024 | 70,000 | 4,548,169 (4%) | 0% | 4.0 | 280,700 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Sale of securities on an exchange or to another person at price $ 23.55 per share. | 11 Nov 2024 | 230,000 | 4,478,169 (4%) | 0% | 23.5 | 5,416,040 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Gift of securities by or to the insider at price $ 0.00 per share. | 22 Aug 2024 | 5,100 | 4,478,169 (4%) | 0% | 0 | Common Stock, par value $0.001 per share | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 21 Aug 2024 | 15,000 | 363,874 (0%) | 0% | 4.0 | 60,150 | Common stock, par value $0.001 per share |
| David S. Tierney | Director | Sale of securities on an exchange or to another person at price $ 20.10 per share. | 21 Aug 2024 | 15,000 | 348,874 (0%) | 0% | 20.1 | 301,455 | Common stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Aug 2024 | 15,000 | 188,931 | - | - | Options to purchase common stock | |
| Steven R. Miller | Chief Op. & Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.26 per share. | 20 Aug 2024 | 50,000 | 775,124 (0%) | 0% | 20.3 | 1,013,050 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.58 per share. | 20 Aug 2024 | 50,000 | 675,124 (0%) | 0% | 20.6 | 1,029,250 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Op. & Scientific Officer | Sale of securities on an exchange or to another person at price $ 20.21 per share. | 20 Aug 2024 | 50,000 | 725,124 (0%) | 0% | 20.2 | 1,010,600 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Gift of securities by or to the insider at price $ 0.00 per share. | 15 Aug 2024 | 45,000 | 4,483,269 (4%) | 0% | 0 | Common Stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 18.04 per share. | 09 Aug 2024 | 100,000 | 51,391 (0%) | 0% | 18.0 | 1,804,000 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2024 | 100,000 | 950,575 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 09 Aug 2024 | 100,000 | 151,391 (0%) | 0% | 4.0 | 401,000 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.86 per share. | 09 Aug 2024 | 30,000 | 42,369 (0%) | 0% | 2.9 | 85,800 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 18.44 per share. | 09 Aug 2024 | 6,058 | 12,369 (0%) | 0% | 18.4 | 111,710 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Aug 2024 | 30,000 | 804,019 | - | - | Options to purchase common stock | |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 18.42 per share. | 09 Aug 2024 | 30,000 | 12,369 (0%) | 0% | 18.4 | 552,600 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 16.07 per share. | 07 Jun 2024 | 7,541 | 18,427 (0%) | 0% | 16.1 | 121,184 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 05 Jun 2024 | 80,000 | 131,391 (0%) | 0% | 4.0 | 320,800 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 16.16 per share. | 05 Jun 2024 | 80,000 | 51,391 (0%) | 0% | 16.2 | 1,292,800 | Common stock, par value $0.001 per share |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Jun 2024 | 80,000 | 1,050,575 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 15.98 per share. | 04 Jun 2024 | 17,323 | 234,824 (0%) | 0% | 16.0 | 276,735 | Common stock, par value $0.001 per share |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 04 Jun 2024 | 40,000 | 252,147 (0%) | 0% | 4.0 | 160,400 | Common stock, par value $0.001 per share |
| Richard J. Daly | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 04 Jun 2024 | 40,000 | 1,731,012 | - | - | Options to purchase common stock | |
| Molly Harper | Director | Sale of securities on an exchange or to another person at price $ 16.30 per share. | 03 Jun 2024 | 5,333 | 0 (0%) | 0% | 16.3 | 86,949 | Common Stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Apr 2024 | 25,000 | 203,931 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Sale of securities on an exchange or to another person at price $ 15.68 per share. | 08 Apr 2024 | 25,000 | 348,874 (0%) | 0% | 15.7 | 392,000 | Common stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 08 Apr 2024 | 25,000 | 373,874 (0%) | 0% | 4.0 | 100,250 | Common stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 16.44 per share. | 27 Mar 2024 | 25,000 | 124,433 (0%) | 0% | 16.4 | 411,000 | Common stock, par value $0.001 per share |
| J. Daly Richard | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 1,771,012 | - | - | Restricted Stock Units | |
| David Tierney S. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 228,931 | - | - | Restricted Stock Units | |
| Charles O'Keeffe B. | Director | 15 Feb 2024 | 4,000 | 685,724 (0%) | 0% | - | Common Stock, par value $0.001 per share | ||
| Del Carmen Jeffrey | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 15 Feb 2024 | 3,125 | 25,968 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Elsbernd Brian | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 15 Feb 2024 | 2,353 | 149,433 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Jeffrey Carmen Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 10,667 | 29,093 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Gary Ingenito | Chief Med. & Reg. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 15 Feb 2024 | 2,435 | 51,391 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 9,667 | 151,786 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| A. Donald Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 438,333 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| R. Miller Steven | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 13,667 | 1,621,289 | - | - | Restricted Stock Units | |
| Steven R. Miller | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 13,667 | 825,124 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Harper Molly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 5,333 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| B. Charles O'Keeffe | Director | 15 Feb 2024 | 4,000 | 228,931 | - | - | Restricted Stock Units | ||
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 16,667 | 554,259 | - | - | Restricted Stock Units | |
| J. Daly Richard | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 213,333 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Denkhaus A. Donald | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 188,931 | - | - | Restricted Stock Units | |
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 10,000 | 53,826 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 15 Feb 2024 | 6,025 | 25,541 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 16,667 | 31,566 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 10,667 | 834,019 | - | - | Restricted Stock Units | |
| Elsbernd Brian | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 9,667 | 1,012,823 | - | - | Restricted Stock Units | |
| Harper Molly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 125,431 | - | - | Restricted Stock Units | |
| S. David Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 4,000 | 348,874 (0%) | 0% | - | Common Stock, Par Value $0.001 per share | |
| Daly J. Richard | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 15 Feb 2024 | 1,186 | 212,147 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Ingenito Gary | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2024 | 10,000 | 1,130,575 | - | - | Restricted Stock Units | |
| A. Donald Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Feb 2024 | 40,000 | 192,931 | - | - | Options to purchase common stock | |
| A. Denkhaus Donald | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.01 per share. | 05 Feb 2024 | 40,000 | 434,333 (0%) | 0% | 4.0 | 160,400 | Common Stock, par value $0.001 per share |
| J. McEnany Patrick | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2024 | 26,333 | 4,411,589 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| J. McEnany Patrick | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2024 | 116,667 | 4,528,256 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| McEnany Patrick J. | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2024 | 26,333 | 2,709,412 | - | - | Restricted Stock Units | |
| Patrick J. McEnany | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Jan 2024 | 116,667 | 2,592,745 | - | - | Restricted Stock Units | |
| Tierney David S. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2024 | 10,000 | 232,931 | - | - | Options to purchase common stock | |
| Charles O'Keeffe B. | Director | 02 Jan 2024 | 60,000 | 681,724 (0%) | 0% | 1.1 | 67,800 | Common Stock, par value $0.001 per share | |
| Charles B. O'Keeffe | Director | 02 Jan 2024 | 60,000 | 232,931 | - | - | Options to purchase common stock | ||
| Tierney S. David | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 02 Jan 2024 | 10,000 | 344,874 (0%) | 0% | 1.1 | 11,300 | Common Stock, Par Value $0.001 per share |
| McEnany J. Patrick | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 02 Jan 2024 | 250,000 | 4,385,256 (4%) | 0% | 1.1 | 282,500 | Common stock, par value $0.001 per share |
| McEnany J. Patrick | Director, Chairman of Board of Directors | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2024 | 250,000 | 2,735,745 | - | - | Options to purchase common stock | |
| Richard Daly J. | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2024 | 1,365,319 | 1,564,486 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jan 2024 | 210,526 | 1,775,012 | - | - | Restricted Stock Units | |
| S. David Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 334,874 (0%) | 0% | - | Common Stock, Par Value $0.001 per share | |
| R. Miller Steven | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 14,000 | 811,457 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Ingenito Gary | Chief Med. & Reg. Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2023 | 3,541 | 43,826 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Charles B. O'Keeffe | Director | 27 Dec 2023 | 1,333 | 621,724 (0%) | 0% | - | Common Stock, par value $0.001 per share | ||
| Steven Miller R. | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 14,000 | 1,634,956 | - | - | Restricted Stock Units | |
| Elsbernd Brian | Chief Compliance/Legal Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2023 | 2,623 | 142,119 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Daly Richard J. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 199,167 | - | - | Restricted Stock Units | |
| Jeffrey Carmen Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 8,666 | 22,265 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| J. McEnany Patrick | Director, President and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2023 | 10,362 | 4,135,256 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Alicia Grande | VP, Treasurer and CFO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2023 | 3,410 | 55,813 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Carmen Del Jeffrey | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 8,666 | 844,686 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 6,666 | 144,742 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| McEnany Patrick J. | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 26,333 | 4,145,618 (4%) | 0% | - | Common Stock, par value $0.001 per share | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 129,431 | - | - | Restricted Stock Units | |
| Preethi Sundaram | Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2023 | 2,409 | 14,899 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 8,666 | 1,187,168 | - | - | Restricted Stock Units | |
| Harper Molly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 1,333 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 6,666 | 17,308 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Del Jeffrey Carmen | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Dec 2023 | 3,839 | 18,426 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Donald Denkhaus A. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 232,931 | - | - | Restricted Stock Units | |
| O'Keeffe Charles B. | Director | 27 Dec 2023 | 1,333 | 292,931 | - | - | Restricted Stock Units | ||
| Gary Ingenito | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 9,000 | 47,367 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| S. Tierney David | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 242,931 | - | - | Restricted Stock Units | |
| Ingenito Gary | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 9,000 | 1,140,575 | - | - | Restricted Stock Units | |
| J. McEnany Patrick | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 26,333 | 2,985,745 | - | - | Restricted Stock Units | |
| Daly Richard J. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 209,333 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 8,666 | 59,223 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| A. Denkhaus Donald | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 1,333 | 394,333 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Preethi Sundaram | Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 6,666 | 570,926 | - | - | Restricted Stock Units | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Dec 2023 | 6,666 | 1,022,490 | - | - | Restricted Stock Units | |
| Molly Harper | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.78 per share. | 15 Dec 2023 | 10,000 | 10,000 (0%) | 0% | 5.8 | 57,800 | Common stock, par value $0.001 per share |
| Molly Harper | Director | Sale of securities on an exchange or to another person at price $ 14.37 per share. | 15 Dec 2023 | 10,000 | 0 (0%) | 0% | 14.4 | 143,700 | Common stock, par value $0.001 per share |
| Harper Molly | Director | Sale of securities on an exchange or to another person at price $ 14.43 per share. | 15 Dec 2023 | 4,000 | 0 (0%) | 0% | 14.4 | 57,720 | Common stock, par value $0.001 per share |
| Harper Molly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Dec 2023 | 10,000 | 130,764 | - | - | Options to purchase common stock | |
| Tierney S. David | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2023 | 50,000 | 244,264 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 12 Dec 2023 | 50,000 | 383,541 (0%) | 0% | 1.1 | 56,500 | Common stock, par value $0.001 per share |
| David Tierney S. | Director | Sale of securities on an exchange or to another person at price $ 13.32 per share. | 12 Dec 2023 | 50,000 | 333,541 (0%) | 0% | 13.3 | 666,250 | Common stock, par value $0.001 per share |
| Steven Miller R. | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 11 Dec 2023 | 150,000 | 797,457 (0%) | 0% | 1.1 | 169,500 | Common stock, par value $0.001 per share |
| Miller Steven R. | Chief Op. & Scientific Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Dec 2023 | 150,000 | 1,648,956 | - | - | Options to purchase common stock | |
| B. O'Keeffe Charles | Director | 08 Dec 2023 | 29,524 | 290,024 | - | - | Options to purchase common stock | ||
| Grande Alicia | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2023 | 60,000 | 1,195,834 | - | - | Options to purchase common stock | |
| Elsbernd Brian | Chief Compliance/Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 147,621 | 1,007,955 | - | - | Options to purchase common stock | |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 14.30 per share. | 08 Dec 2023 | 20,000 | 50,557 (0%) | 0% | 14.3 | 286,000 | Common Stock, par value $0.001 per share |
| Donald Denkhaus A. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 29,524 | 230,024 | - | - | Options to purchase common stock | |
| Grande Alicia | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 08 Dec 2023 | 40,000 | 90,557 (0%) | 0% | 1.1 | 45,200 | Common stock, par value $0.001 per share |
| McEnany J. Patrick | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 10,601 | 3,012,078 | - | - | Restricted Stock Units | |
| Harper Molly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 4,240 | 140,764 | - | - | Restricted Stock Units | |
| David S. Tierney | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 29,524 | 290,024 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 22,049 | 1,149,575 | - | - | Restricted Stock Units | |
| Tierney David S. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 4,240 | 294,264 | - | - | Restricted Stock Units | |
| Thompson Tamar | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 4,240 | 73,764 | - | - | Restricted Stock Units | |
| Charles B. O'Keeffe | Director | 08 Dec 2023 | 4,240 | 294,264 | - | - | Restricted stock units | ||
| Grande Alicia | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 08 Dec 2023 | 60,000 | 110,557 (0%) | 0% | 1.1 | 67,800 | Common Stock, par value $0.001 per share |
| Donald Denkhaus A. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 4,240 | 234,264 | - | - | Restricted Stock Units | |
| Tamar Thompson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 29,524 | 69,524 | - | - | Options to purchase common stock | |
| Del Jeffrey Carmen | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 167,918 | 829,235 | - | - | Options to purchase common stock | |
| Carmen Jeffrey Del | Chief Commercial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 24,117 | 853,352 | - | - | Restricted Stock Units | |
| Grande Alicia | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Dec 2023 | 40,000 | 1,255,834 | - | - | Options to purchase common stock | |
| McEnany J. Patrick | Director, Chairman and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 73,810 | 3,001,477 | - | - | Options to purchase common stock | |
| Sundaram Preethi | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 143,193 | 557,027 | - | - | Options to purchase common stock | |
| Gary Ingenito | Chief Med. & Reg. Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 153,526 | 1,127,526 | - | - | Options to purchase common stock | |
| Preethi Sundaram | Chief Strategy Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 20,565 | 577,592 | - | - | Restricted Stock Units | |
| Grande Alicia | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 13.74 per share. | 08 Dec 2023 | 30,000 | 80,557 (0%) | 0% | 13.7 | 412,200 | Common Stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 14.25 per share. | 08 Dec 2023 | 20,000 | 70,557 (0%) | 0% | 14.3 | 285,000 | Common Stock, par value $0.001 per share |
| Miller Steven R. | Chief Op. & Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 248,004 | 1,763,338 | - | - | Options to purchase common stock | |
| R. Miller Steven | Chief Op. & Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 35,618 | 1,798,956 | - | - | Restricted Stock Units | |
| Harper Molly | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 29,524 | 136,524 | - | - | Options to purchase common stock | |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 13.79 per share. | 08 Dec 2023 | 30,000 | 50,557 (0%) | 0% | 13.8 | 413,580 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2023 | 21,201 | 1,029,156 | - | - | Restricted Stock Units | |
| Daly J. Richard | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Dec 2023 | 60,000 | 200,500 | - | - | Options to purchase common stock | |
| J. Richard Daly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 07 Dec 2023 | 60,000 | 208,000 (0%) | 0% | 1.1 | 67,800 | Common Stock, par value $0.001 per share |
| Ingenito Gary | Chief Med. & Reg. Officer | Sale of securities on an exchange or to another person at price $ 14.02 per share. | 06 Dec 2023 | 50,000 | 38,367 (0%) | 0% | 14.0 | 701,000 | Common stock, par value $0.001 per share |
| Ingenito Gary | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 06 Dec 2023 | 50,000 | 88,367 (0%) | 0% | 1.1 | 56,500 | Common stock, par value $0.001 per share |
| Ingenito Gary | Chief Med. & Reg. Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Dec 2023 | 50,000 | 974,000 | - | - | Options to purchase common stock | |
| R. Miller Steven | Chief Op. & Scientific Officer | Sale of securities on an exchange or to another person at price $ 14.24 per share. | 05 Dec 2023 | 40,000 | 647,457 (0%) | 0% | 14.2 | 569,600 | Common stock, par value $0.001 per share |
| Donald Denkhaus A. | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Aug 2023 | 60,000 | 200,500 | - | - | Options to purchase common stock | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 03 Aug 2023 | 60,000 | 393,000 (0%) | 0% | 1.1 | 67,800 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jun 2023 | 10,000 | 661,317 | - | - | Restricted Stock Units | |
| Carmen Jeffrey Del | Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 0.00 per share. | 27 Jun 2023 | 3,942 | 13,599 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Jun 2023 | 10,000 | 17,541 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 15 May 2023 | 26,151 | 3,971,587 (3%) | 0% | 0.8 | 20,659 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 13.23 per share. | 15 May 2023 | 26,151 | 3,945,436 (3%) | 0% | 13.2 | 345,978 | Common stock, par value $0.001 per share |
| Patrick J. McEnany | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 173,849 | 2,927,667 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 May 2023 | 26,151 | 3,101,516 | - | - | Options to purchase common stock | |
| Patrick J. McEnany | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 15 May 2023 | 173,849 | 4,119,285 (3%) | 0% | 0.8 | 137,341 | Common stock, par value $0.001 per share |
| Richard J. Daly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 May 2023 | 50,000 | 260,500 | - | - | Options to purchase common stock | |
| Richard J. Daly | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 12 May 2023 | 50,000 | 148,000 (0%) | 0% | 0.8 | 39,500 | Common Stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2023 | 20,000 | 260,500 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 11 May 2023 | 20,000 | 333,541 (0%) | 0% | 0.8 | 15,800 | Common stock, par value $0.001 per share |
| Steven R. Miller | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 May 2023 | 100,000 | 1,515,334 | - | - | Options to purchase common stock | |
| Steven R. Miller | Chief Operating Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 11 May 2023 | 100,000 | 687,457 (0%) | 0% | 0.8 | 79,000 | Common stock, par value $0.001 per share |
| Philip H. Coelho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2023 | 50,000 | 260,500 | - | - | Options to purchase Common Stock | |
| Philip H. Coelho | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 04 May 2023 | 50,000 | 204,887 (0%) | 0% | 0.8 | 39,500 | Common stock, par value $0.001 per share |
| David S. Tierney | Director | Sale of securities on an exchange or to another person at price $ 16.83 per share. | 05 Apr 2023 | 30,000 | 313,541 (0%) | 0% | 16.8 | 504,900 | Common stock, par value $0.001 per share |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Apr 2023 | 30,000 | 280,500 | - | - | Options to purchase common stock | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 05 Apr 2023 | 30,000 | 343,541 (0%) | 0% | 0.8 | 23,700 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 16.70 per share. | 29 Mar 2023 | 20,983 | 7,541 (0%) | 0% | 16.7 | 350,416 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Mar 2023 | 19,017 | 671,317 | - | - | Options to purchase common stock | |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 29 Mar 2023 | 20,983 | 690,334 | - | - | Options to purchase common stock | |
| Carmen Jeffrey Del | Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 16.69 per share. | 29 Mar 2023 | 19,017 | 7,541 (0%) | 0% | 16.7 | 317,394 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.21 per share. | 29 Mar 2023 | 19,017 | 26,558 (0%) | 0% | 4.2 | 80,062 | Common stock, par value $0.001 per share |
| Carmen Jeffrey Del | Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 2.24 per share. | 29 Mar 2023 | 20,983 | 28,524 (0%) | 0% | 2.2 | 47,002 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 28 Mar 2023 | 50,000 | 100,557 (0%) | 0% | 1.1 | 56,500 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.37 per share. | 28 Mar 2023 | 10,000 | 50,557 (0%) | 0% | 16.4 | 163,700 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.52 per share. | 28 Mar 2023 | 10,000 | 60,557 (0%) | 0% | 16.5 | 165,200 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.55 per share. | 28 Mar 2023 | 10,000 | 70,557 (0%) | 0% | 16.6 | 165,500 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.60 per share. | 28 Mar 2023 | 28,216 | 80,557 (0%) | 0% | 16.6 | 468,386 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 28 Mar 2023 | 58,216 | 108,773 (0%) | 0% | 0.8 | 45,991 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Mar 2023 | 50,000 | 1,295,834 | - | - | Options to purchase common stock | |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Mar 2023 | 58,216 | 1,345,834 | - | - | Options to purchase common stock | |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.67 per share. | 28 Mar 2023 | 10,000 | 50,557 (0%) | 0% | 16.7 | 166,700 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.70 per share. | 28 Mar 2023 | 20,000 | 60,557 (0%) | 0% | 16.7 | 334,000 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.72 per share. | 28 Mar 2023 | 20,000 | 80,557 (0%) | 0% | 16.7 | 334,400 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 22 Mar 2023 | 38,524 | 89,081 (0%) | 0% | 0.8 | 30,434 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.79 per share. | 22 Mar 2023 | 3,260 | 53,817 (0%) | 0% | 0.8 | 2,575 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.41 per share. | 22 Mar 2023 | 3,260 | 50,557 (0%) | 0% | 16.4 | 53,497 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Sale of securities on an exchange or to another person at price $ 16.51 per share. | 22 Mar 2023 | 38,524 | 50,557 (0%) | 0% | 16.5 | 636,031 | Common stock, par value $0.001 per share |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2023 | 3,260 | 1,442,574 | - | - | Options to purchase common stock | |
| Alicia Grande | VP, Treasurer and CFO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Mar 2023 | 38,524 | 1,404,050 | - | - | Options to purchase common stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 1.13 per share. | 20 Mar 2023 | 50,000 | 188,076 (0%) | 0% | 1.1 | 56,500 | Common Stock, par value $0.001 per share |
| Brian Elsbernd | Chief Compliance/Legal Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 20 Mar 2023 | 50,000 | 860,334 | - | - | Options to Purchase Common Stock | |
| Brian Elsbernd | Chief Compliance/Legal Officer | Sale of securities on an exchange or to another person at price $ 16.07 per share. | 20 Mar 2023 | 50,000 | 138,076 (0%) | 0% | 16.1 | 803,450 | Common Stock, par value $0.001 per share |
| Charles B. O'Keeffe | Director | 15 Feb 2023 | 4,000 | 620,391 (0%) | 0% | - | Common Stock, par value $0.001 per share | ||
| Charles B. O'Keeffe | Director | 15 Feb 2023 | 4,000 | 260,500 | - | - | Restricted Stock Units | ||
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 4,000 | 313,541 (0%) | 0% | - | Common Stock, Par Value $0.001 per share | |
| David S. Tierney | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 4,000 | 310,500 | - | - | Restricted Stock Units | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 4,000 | 333,000 (0%) | 0% | - | Common Stock, par value $0.001 per share | |
| Donald A. Denkhaus | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 4,000 | 260,500 | - | - | Restricted Stock Units | |
| Philip H. Coelho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2023 | 4,000 | 310,500 | - | - | Restricted Stock Units | |
| Philip H. Coelho | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 4,000 | 154,887 (0%) | 0% | - | Common stock, par value $0.001 per share | |
| Patrick J. McEnany | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Feb 2023 | 58,333 | 3,959,640 (3%) | 0% | - | Common Stock, par value $0.001 per share |