| 
                    Mark A. Meltz
                 | 
                COO GENERAL COUNSEL SECRETARY | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.59 per share.  | 
                01 Mar 2024 | 
                558 | 
                
                    
                        27,578
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        1,445
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                CHIEF MEDICAL OFFICER | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.59 per share.  | 
                01 Mar 2024 | 
                558 | 
                
                    
                        67,588
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        1,445
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                CHIEF FINANCIAL OFFICER | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.59 per share.  | 
                01 Mar 2024 | 
                1,506 | 
                
                    
                        64,087
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        3,901
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Krishnamohan Neha
                 | 
                Chief Financial Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.25 per share.  | 
                01 Dec 2023 | 
                1,459 | 
                
                    
                        65,593
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.3 | 
                
                    
                        3,283
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Meltz A. Mark
                 | 
                COO General Counsel Secretary | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.25 per share.  | 
                01 Dec 2023 | 
                541 | 
                
                    
                        28,136
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.2 | 
                
                    
                        1,217
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Thomas Williams Richard
                 | 
                Chief Medical Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 2.25 per share.  | 
                01 Dec 2023 | 
                541 | 
                
                    
                        68,146
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.2 | 
                
                    
                        1,217
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Dean Jonathan Mitchell
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Jun 2023 | 
                25,000 | 
                
                    
                        25,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Jun 2023 | 
                25,000 | 
                
                    
                        25,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Keith Flaherty
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Jun 2023 | 
                25,000 | 
                
                    
                        25,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Laurie Smaldone Alsup
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Jun 2023 | 
                25,000 | 
                
                    
                        25,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Helen Sabzevari
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Jun 2023 | 
                25,000 | 
                
                    
                        25,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Melissa B. Epperly
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Jun 2023 | 
                25,000 | 
                
                    
                        25,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Secretary | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.30 per share.  | 
                01 Jun 2023 | 
                541 | 
                
                    
                        29,218
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                4.3 | 
                
                    
                        2,326
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.30 per share.  | 
                01 Jun 2023 | 
                541 | 
                
                    
                        69,228
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                4.3 | 
                
                    
                        2,326
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 4.30 per share.  | 
                01 Jun 2023 | 
                1,459 | 
                
                    
                        68,511
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                4.3 | 
                
                    
                        6,274
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.80 per share.  | 
                08 May 2023 | 
                1,550,956 | 
                
                    
                        3,525,957
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.8 | 
                
                    
                        4,342,677
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.80 per share.  | 
                08 May 2023 | 
                229,044 | 
                
                    
                        520,711
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.8 | 
                
                    
                        641,323
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.82 per share.  | 
                04 May 2023 | 
                490,511 | 
                
                    
                        1,368,338
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.8 | 
                
                    
                        1,383,241
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.75 per share.  | 
                04 May 2023 | 
                83,459 | 
                
                    
                        877,827
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.7 | 
                
                    
                        229,512
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.75 per share.  | 
                04 May 2023 | 
                312,991 | 
                
                    
                        4,738,453
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.7 | 
                
                    
                        860,725
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.82 per share.  | 
                04 May 2023 | 
                490,512 | 
                
                    
                        1,368,339
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.8 | 
                
                    
                        1,383,244
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.75 per share.  | 
                04 May 2023 | 
                83,459 | 
                
                    
                        877,827
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.7 | 
                
                    
                        229,512
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.67 per share.  | 
                28 Apr 2023 | 
                220,610 | 
                
                    
                        4,425,462
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.7 | 
                
                    
                        589,029
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.55 per share.  | 
                28 Apr 2023 | 
                60,998 | 
                
                    
                        610,998
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        155,545
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.55 per share.  | 
                28 Apr 2023 | 
                228,754 | 
                
                    
                        3,737,784
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        583,323
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.55 per share.  | 
                28 Apr 2023 | 
                60,997 | 
                
                    
                        610,997
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.5 | 
                
                    
                        155,542
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.62 per share.  | 
                28 Apr 2023 | 
                124,544 | 
                
                    
                        735,542
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        326,305
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.62 per share.  | 
                28 Apr 2023 | 
                467,068 | 
                
                    
                        4,204,852
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        1,223,718
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.62 per share.  | 
                28 Apr 2023 | 
                124,545 | 
                
                    
                        735,542
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.6 | 
                
                    
                        326,308
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.67 per share.  | 
                28 Apr 2023 | 
                58,826 | 
                
                    
                        794,368
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.7 | 
                
                    
                        157,065
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 2.67 per share.  | 
                28 Apr 2023 | 
                58,826 | 
                
                    
                        794,368
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                2.7 | 
                
                    
                        157,065
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Secretary | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.21 per share.  | 
                01 Mar 2023 | 
                638 | 
                
                    
                        27,286
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                5.2 | 
                
                    
                        3,324
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.21 per share.  | 
                01 Mar 2023 | 
                638 | 
                
                    
                        67,295
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                5.2 | 
                
                    
                        3,324
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 5.21 per share.  | 
                01 Mar 2023 | 
                1,721 | 
                
                    
                        67,378
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                5.2 | 
                
                    
                        8,966
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jill DeSimone
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                01 Mar 2023 | 
                50,000 | 
                
                    
                        50,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                17 Feb 2023 | 
                550,000 | 
                
                    
                        550,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director, Ten Percent Owner | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                17 Feb 2023 | 
                550,000 | 
                
                    
                        550,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Other type of transaction at price $ 0.00 per share.  | 
                17 Feb 2023 | 
                1,100,000 | 
                
                    
                        1,975,001
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Secretary | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                10 Feb 2023 | 
                215,000 | 
                
                    
                        215,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Nima Farzan
                 | 
                Director, Chief Executive Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                10 Feb 2023 | 
                750,000 | 
                
                    
                        750,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                10 Feb 2023 | 
                215,000 | 
                
                    
                        215,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                10 Feb 2023 | 
                215,000 | 
                
                    
                        215,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Secretary | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.75 per share.  | 
                01 Dec 2022 | 
                541 | 
                
                    
                        27,924
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                7.8 | 
                
                    
                        4,193
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.75 per share.  | 
                01 Dec 2022 | 
                541 | 
                
                    
                        67,933
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                7.8 | 
                
                    
                        4,193
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Payment of exercise price or tax liability using portion of securities received from the company at price $ 7.75 per share.  | 
                01 Dec 2022 | 
                1,459 | 
                
                    
                        69,099
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                7.7 | 
                
                    
                        11,307
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Secretary | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                01 Sep 2022 | 
                25,000 | 
                
                    
                        28,465
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        0
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                01 Sep 2022 | 
                25,000 | 
                
                    
                        68,474
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        0
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                01 Sep 2022 | 
                67,500 | 
                
                    
                        69,015
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        0
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Dean Jonathan Mitchell
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Keith Flaherty
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Laurie Smaldone Alsup
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Helen Sabzevari
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Melissa B. Epperly
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Michael Rome
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                13 Jun 2022 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Purchase of securities on an exchange or from another person at price $ 8.64 per share.  | 
                11 Mar 2022 | 
                15,000 | 
                
                    
                        17,333
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                8.6 | 
                
                    
                        129,600
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Purchase of securities on an exchange or from another person at price $ 8.37 per share.  | 
                11 Mar 2022 | 
                25,000 | 
                
                    
                        42,333
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                8.4 | 
                
                    
                        209,250
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director | 
                 Purchase of securities on an exchange or from another person at price $ 9.96 per share.  | 
                11 Feb 2022 | 
                9,000 | 
                
                    
                        3,509,030
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                10.0 | 
                
                    
                        89,640
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director | 
                 Purchase of securities on an exchange or from another person at price $ 9.89 per share.  | 
                11 Feb 2022 | 
                10,000 | 
                
                    
                        3,500,030
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                9.9 | 
                
                    
                        98,900
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director | 
                 Purchase of securities on an exchange or from another person at price $ 9.98 per share.  | 
                11 Feb 2022 | 
                20,700 | 
                
                    
                        3,490,030
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                10.0 | 
                
                    
                        206,586
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L. Gordon
                 | 
                Director | 
                 Purchase of securities on an exchange or from another person at price $ 10.22 per share.  | 
                11 Feb 2022 | 
                156,000 | 
                
                    
                        3,469,330
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                10.2 | 
                
                    
                        1,594,320
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Treasurer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Feb 2022 | 
                135,000 | 
                
                    
                        135,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Nima Farzan
                 | 
                Director, Chief Executive Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Feb 2022 | 
                400,000 | 
                
                    
                        400,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Feb 2022 | 
                135,000 | 
                
                    
                        135,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Feb 2022 | 
                185,000 | 
                
                    
                        185,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Dean Jonathan Mitchell
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Jun 2021 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Keith Flaherty
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Jun 2021 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Laurie Smaldone Alsup
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Jun 2021 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Melissa B. Epperly
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                11 Jun 2021 | 
                20,250 | 
                
                    
                        20,250
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Neha Krishnamohan
                 | 
                Chief Financial Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                07 Jun 2021 | 
                270,000 | 
                
                    
                        270,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Mark A. Meltz
                 | 
                COO General Counsel Treasurer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Feb 2021 | 
                100,000 | 
                
                    
                        100,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Nima Farzan
                 | 
                Director, Chief Executive Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Feb 2021 | 
                275,000 | 
                
                    
                        275,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee stock option (right to buy) | 
            
        
            
                
                | 
                    Eric Anthony Murphy
                 | 
                Chief Scientific Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Feb 2021 | 
                60,000 | 
                
                    
                        60,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Richard Thomas Williams
                 | 
                Chief Medical Officer | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                12 Feb 2021 | 
                100,000 | 
                
                    
                        100,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Employee Stock Option (right to buy) | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                50,501 | 
                
                    
                        50,501
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                243,494 | 
                
                    
                        543,494
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                118,398 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series C Preferred Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                2,651,042 | 
                
                    
                        3,194,536
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                2,651,042 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series B Preferred Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                118,794 | 
                
                    
                        3,313,330
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                243,494 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series A Preferred Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                24,637 | 
                
                    
                        84,599
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                24,555 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series C Preferred Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                9,461 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series B Preferred Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                50,501 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series A Preferred Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                9,461 | 
                
                    
                        59,962
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                9,171,643 | 
                
                    
                        9,671,643
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        0
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                298,465 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series A Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                6,347,893 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series A Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                166,667 | 
                
                    
                        291,667
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        0
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                500,001 | 
                
                    
                        875,001
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        0
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                48,376 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series C Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                145,128 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series C Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                157,222 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series C Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                18,641 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series B Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                55,922 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series B Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                2,666,002 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series B Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                   | 
                07 Dec 2020 | 
                99,488 | 
                
                    
                        0
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Series A Preferred Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 20.00 per share.  | 
                03 Dec 2020 | 
                500,000 | 
                
                    
                        500,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                20 | 
                
                    
                        10,000,000
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 20.00 per share.  | 
                03 Dec 2020 | 
                375,000 | 
                
                    
                        375,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                20 | 
                
                    
                        7,500,000
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 20.00 per share.  | 
                03 Dec 2020 | 
                125,000 | 
                
                    
                        125,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                20 | 
                
                    
                        2,500,000
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 20.00 per share.  | 
                02 Dec 2020 | 
                300,000 | 
                
                    
                        300,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                20 | 
                
                    
                        6,000,000
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                02 Dec 2020 | 
                40,501 | 
                
                    
                        40,501
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Carl L Gordon
                 | 
                Director, Ten Percent Owner | 
                 Purchase of securities on an exchange or from another person at price $ 20.00 per share.  | 
                02 Dec 2020 | 
                450,000 | 
                
                    
                        450,000
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                20 | 
                
                    
                        9,000,000
                    
                 | 
                Common Stock | 
            
        
            
                
                | 
                    Jim Tananbaum
                 | 
                Director, Ten Percent Owner | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                02 Dec 2020 | 
                40,501 | 
                
                    
                        40,501
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) | 
            
        
            
                
                | 
                    Michael Rome
                 | 
                Director | 
                 Grant, award, or other acquisition of securities at price $ 0.00 per share.  | 
                02 Dec 2020 | 
                40,501 | 
                
                    
                        40,501
                    
                    
                 | 
                
                    
                       -
                    
                 | 
                 | 
                
                    
                        -
                    
                 | 
                Stock Option (right to buy) |