XNAS 01 May, 2026 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Ali Behbahani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Mar 2026 | 242,945 | 242,945 | - | - | Pre-Funded Warrants | |
| Ali Behbahani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 11.11 per share. | 10 Mar 2026 | 207,100 | 1,297,893 | - | 11.1 | 2,300,881 | Common Stock |
| Loic A Vincent | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2026 | 35,000 | 35,000 | - | - | Stock Option (Right to Buy) | |
| Oliver Dolan | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2026 | 15,000 | 15,000 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Cerio | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2026 | 23,000 | 23,000 | - | - | Stock Option (Right to Buy) | |
| Todd Chappell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2026 | 38,000 | 38,000 | - | - | Stock Option (Right to Buy) | |
| Ram Aiyar | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2026 | 40,000 | 40,000 | - | 0 | Common Stock | |
| Ram Aiyar | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Feb 2026 | 80,000 | 80,000 | - | - | Stock Option (Right to Buy) | |
| Loic A Vincent | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2025 | 21,715 | 21,715 | - | 0 | Common Stock | |
| Oliver Dolan | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2025 | 21,482 | 21,482 | - | 0 | Common Stock | |
| Jeffrey Cerio | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2025 | 41,902 | 41,902 | - | 0 | Common Stock | |
| Todd Chappell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2025 | 20,132 | 20,132 | - | 0 | Common Stock | |
| Rachel Meyers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2025 | 6,010 | 6,010 | - | - | Stock Option (Right to Buy) | |
| Jean-Francois Formela | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2025 | 6,010 | 6,010 | - | - | Stock Option (Right to Buy) | |
| Timothy R. Pearson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2025 | 6,010 | 6,010 | - | - | Stock Option (Right to Buy) | |
| Ali Behbahani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2025 | 6,010 | 6,010 | - | - | Stock Option (Right to Buy) | |
| Nessan Bermingham | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2025 | 6,010 | 6,010 | - | - | Stock Option (Right to Buy) | |
| Katharine Knobil | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2025 | 6,010 | 6,010 | - | - | Stock Option (Right to Buy) | |
| Loic A Vincent | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 70,000 | 70,000 | - | - | Stock Option (Right to Buy) | |
| Oliver Dolan | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Apr 2025 | 20,000 | 20,000 | - | - | Stock Option (Right to Buy) | |
| Jeffrey Cerio | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2025 | 29,000 | 29,000 | - | - | Stock Option (Right to Buy) | |
| Olukemi Olugemo | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2025 | 42,000 | 42,000 | - | - | Stock Option (Right to Buy) | |
| Todd Chappell | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2025 | 34,500 | 34,500 | - | - | Stock Option (Right to Buy) | |
| Vineet Agarwal | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2025 | 30,000 | 30,000 | - | - | Stock Option (Right to Buy) | |
| Ram Aiyar | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Feb 2025 | 100,000 | 100,000 | - | - | Stock Option (Right to Buy) | |
| Vineet Agarwal | Chief Financial Officer | 11 Nov 2024 | 800 | 30,807 | - | - | Stock Option (Right to Buy) | ||
| Vineet Agarwal | Chief Financial Officer | 11 Nov 2024 | 800 | 0 | - | 70 | 56,000 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 11 Nov 2024 | 800 | 800 | - | 11.7 | 9,344 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 115 | 7,914 | - | 74.6 | 8,575 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 953 | 45,594 | - | - | Stock Option (Right to Buy) | ||
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 2,023 | 8,193 | - | 71.5 | 144,663 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 164 | 8,029 | - | 73.7 | 12,089 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 56 | 7,858 | - | 76 | 4,256 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 23 | 7,835 | - | 77 | 1,771 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 260 | 7,575 | - | 77.6 | 20,164 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 457 | 7,118 | - | 78.6 | 35,914 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 4,961 | 342 | - | 80.5 | 399,374 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 317 | 25 | - | 81.5 | 25,829 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 25 | 0 | - | 82.9 | 2,072 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 1,815 | 5,303 | - | 79.8 | 144,821 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 9,263 | 31,607 | - | - | Stock Option (Right to Buy) | ||
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 9,263 | 9,263 | - | 11.7 | 108,192 | Common Stock | |
| Vineet Agarwal | Chief Financial Officer | 17 Oct 2024 | 953 | 10,216 | - | 15.0 | 14,276 | Common Stock | |
| Jeffrey Cerio | General Counsel | 03 Sep 2024 | 40,000 | 40,000 | - | - | Stock Option (Right to Buy) | ||
| Katharine Knobil | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Aug 2024 | 9,041 | 9,041 | - | - | Stock Option (Right to Buy) | |
| Rachel Meyers | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 5,190 | 5,190 | - | - | Stock Option (Right to Buy) | |
| David L. Lucchino | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 5,190 | 5,190 | - | - | Stock Option (Right to Buy) | |
| Nessan Bermingham | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 5,190 | 5,190 | - | - | Stock Option (Right to Buy) | |
| Ali Behbahani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 5,190 | 5,190 | - | - | Stock Option (Right to Buy) | |
| Timothy R. Pearson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 5,190 | 5,190 | - | - | Stock Option (Right to Buy) | |
| Jean-Francois Formela | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Jun 2024 | 5,190 | 5,190 | - | - | Stock Option (Right to Buy) | |
| Olukemi Olugemo | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 65,000 | 65,000 | - | - | Stock Option (Right to Buy) | |
| Jean-Francois Formela | Director | Grant, award, or other acquisition of securities at price $ 56.00 per share. | 22 Apr 2024 | 17,857 | 195,074 | - | 56 | 999,992 | Common Stock |
| Ali Behbahani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 56.00 per share. | 22 Apr 2024 | 17,857 | 1,090,793 | - | 56 | 999,992 | Common Stock |