Birchler Brian's most recent trade in Ionis Pharmaceuticals Inc was a trade of 351 Common Stock done at an average price of $48.9 . Disclosure was reported to the exchange on Feb. 27, 2026.
| Stock | Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|---|
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Other type of transaction at price $ 48.87 per share. | 27 Feb 2026 | 351 | 66,598 (0%) | 0% | 48.9 | 17,152 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2026 | 11,991 | 72,426 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 83.03 per share. | 29 Jan 2026 | 6,179 | 66,247 (0%) | 0% | 83.0 | 513,048 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2026 | 25,800 | 79,138 | - | - | Performance Restricted Stock Units | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2026 | 20,089 | 68,915 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2026 | 20,089 | 41,126 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2026 | 9,675 | 50,801 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 75.11 per share. | 15 Jan 2026 | 8,480 | 60,435 (0%) | 0% | 75.1 | 636,933 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2026 | 19,350 | 19,350 | - | - | Non-Qualified Stock Option (right to buy) | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 76.17 per share. | 06 Nov 2025 | 8,000 | 48,826 (0%) | 0% | 76.2 | 609,379 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Oct 2025 | 12,425 | 0 | - | - | Non-Qualified Stock Option (right to buy) | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 72.23 per share. | 14 Oct 2025 | 12,425 | 56,826 (0%) | 0% | 72.2 | 897,398 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 53.77 per share. | 14 Oct 2025 | 12,425 | 69,251 (0%) | 0% | 53.8 | 668,092 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Oct 2025 | 11,475 | 12,425 | - | - | Non-Qualified Stock Option (right to buy) | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 72.03 per share. | 14 Oct 2025 | 11,475 | 56,826 (0%) | 0% | 72.0 | 826,589 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 53.77 per share. | 14 Oct 2025 | 11,475 | 68,301 (0%) | 0% | 53.8 | 617,011 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Other type of transaction at price $ 27.71 per share. | 29 Aug 2025 | 166 | 56,826 (0%) | 0% | 27.7 | 4,600 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Apr 2025 | 1,875 | 61,215 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Apr 2025 | 1,875 | 57,340 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 28.37 per share. | 15 Apr 2025 | 680 | 56,660 (0%) | 0% | 28.4 | 19,292 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Other type of transaction at price $ 28.21 per share. | 28 Feb 2025 | 414 | 55,465 (0%) | 0% | 28.2 | 11,680 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 33,000 | 77,373 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2025 | 22,000 | 53,338 | - | - | Performance Restricted Stock Units | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2025 | 14,283 | 60,451 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Jan 2025 | 14,283 | 63,090 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 32.70 per share. | 15 Jan 2025 | 5,400 | 55,051 (0%) | 0% | 32.7 | 176,580 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2025 | 22,000 | 22,000 | - | - | Non-Qualified Stock Option (right to buy) | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Other type of transaction at price $ 38.67 per share. | 30 Aug 2024 | 12 | 46,168 (0%) | 0% | 38.7 | 464 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Apr 2024 | 1,875 | 44,373 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Apr 2024 | 1,875 | 47,061 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 41.66 per share. | 15 Apr 2024 | 905 | 46,156 (0%) | 0% | 41.7 | 37,698 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | Vice President Level 14 | Other type of transaction at price $ 34.43 per share. | 29 Feb 2024 | 604 | 45,186 (0%) | 0% | 34.4 | 20,793 | Common Stock |
| Ionis Pharma Inc | Birchler Brian | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jan 2024 | 12,080 | 46,248 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Birchler Brian | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jan 2024 | 12,080 | 49,079 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 50.42 per share. | 16 Jan 2024 | 4,497 | 44,582 (0%) | 0% | 50.4 | 226,725 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2024 | 20,400 | 58,328 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jan 2024 | 17,000 | 31,338 | - | - | Performance Restricted Stock Units | |
| Ionis Pharma Inc | Birchler Brian | EVP, Corp and Development Ops | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 02 Jan 2024 | 27,200 | 27,200 | - | - | Non-Qualified Stock Option (right to buy) | |
| Ionis Pharma Inc | Birchler Brian | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Dec 2023 | 11,500 | 15,482 | - | - | Non-Qualified Stock Option (right to buy) | |
| Ionis Pharma Inc | Birchler Brian | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 47.34 per share. | 28 Dec 2023 | 11,500 | 48,028 (0%) | 0% | 47.3 | 544,410 | Common Stock |
| Ionis Pharma Inc | Birchler Brian | EVP, Corp and Development Ops | Payment of exercise price or tax liability using portion of securities received from the company at price $ 50.50 per share. | 28 Dec 2023 | 11,029 | 36,999 (0%) | 0% | 50.5 | 556,965 | Common Stock |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2023 | 1,875 | 27,720 | - | - | Restricted Stock Unit | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2023 | 1,875 | 37,200 (0%) | 0% | 0 | Common Stock | |
| Ionis Pharma Inc | Brian Birchler | EVP, Corp and Development Ops | Sale of securities on an exchange or to another person at price $ 36.50 per share. | 17 Apr 2023 | 672 | 36,528 (0%) | 0% | 36.5 | 24,530 | Common Stock |