1. MARKETS
  2. SECTOR : PHARMA & BIOTECH
  3. INDUSTRY : MAJOR PHARMACEUTICALS
  4. MADRIGAL PHARMACEUTICALS INC
Madrigal Pharmaceuticals Inc
XNAS: MDGL
Momentum Trap
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518.66 4.94 (0.96%)
95.72% Gain from 52W Low
183.8K
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XNAS 04 May, 2026 5:30 PM (EDT)

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Board Meeting
The next board meeting for Madrigal Pharma Inc is on 06 May 2026 for the purpose of Madrigal Pharmaceuticals Inc First Quarter Earnings Result for 2026 See details


Insider Trading disclosures for Madrigal Pharma Inc

The latest disclosure was made by Rebecca A. Taub in Madrigal Pharma Inc where a trade of 491 Common Stock done at an average price of $431.9 was reported to US exchanges on March 6, 2026.

Insider trading is the trading of a company’s securities by individuals with access to confidential or material non-public information about the company. A company is required to report trading by corporate officers, directors, or other company members with significant access to privileged information to the Securities and Exchange Commission (SEC).

Client Name Client Category Action Reported to Exchange Quantity Post Transaction Holding Traded % Avg. Price Value Security Type
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 431.94 per share. 06 Mar 2026 491 452,213 (2%) 0% 431.9 212,083 Common Stock
William John Sibold Director, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 18,743 18,743 - - Stock Option (Right to Buy)
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 431.94 per share. 04 Mar 2026 1,663 161,829 (1%) 0% 431.9 718,316 Common Stock
William John Sibold Director, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 14,995 163,492 (1%) 0% 0 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 431.94 per share. 04 Mar 2026 646 13,826 (0%) 0% 431.9 279,033 Common Stock
Mardi C. Dier EVP and CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 5,215 14,472 (0%) 0% 0 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 429.58 per share. 04 Mar 2026 40 13,086 (0%) 0% 429.6 17,183 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 428.99 per share. 04 Mar 2026 160 13,126 (0%) 0% 429.0 68,639 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 427.85 per share. 04 Mar 2026 80 13,286 (0%) 0% 427.9 34,228 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 426.86 per share. 04 Mar 2026 420 13,366 (0%) 0% 426.9 179,283 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 425.08 per share. 04 Mar 2026 40 13,786 (0%) 0% 425.1 17,003 Common Stock
Mardi C. Dier EVP and CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 6,519 6,519 - - Stock Option (Right to Buy)
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 437.65 per share. 04 Mar 2026 40 12,490 (0%) 0% 437.7 17,506 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 436.69 per share. 04 Mar 2026 80 12,530 (0%) 0% 436.7 34,935 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 435.31 per share. 04 Mar 2026 80 12,610 (0%) 0% 435.3 34,825 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 434.20 per share. 04 Mar 2026 160 12,690 (0%) 0% 434.2 69,472 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 432.55 per share. 04 Mar 2026 116 12,850 (0%) 0% 432.6 50,176 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 430.90 per share. 04 Mar 2026 120 12,966 (0%) 0% 430.9 51,708 Common Stock
David Soergel Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 4,374 11,919 (0%) 0% 0 Common Stock
David Soergel Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 5,467 5,467 - - Stock Option (Right to Buy)
Carole Huntsman Chief Commercial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 4,986 4,986 - - Stock Option (Right to Buy)
Carole Huntsman Chief Commercial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 3,989 13,111 (0%) 0% 0 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 431.94 per share. 04 Mar 2026 419 12,692 (0%) 0% 431.9 180,983 Common Stock
Shannon T. Kelley General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 5,022 5,022 - - Stock Option (Right to Buy)
Shannon T. Kelley General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 04 Mar 2026 4,017 12,498 (0%) 0% 0 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 431.94 per share. 04 Mar 2026 360 12,138 (0%) 0% 431.9 155,498 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 427.21 per share. 02 Mar 2026 1,183 9,257 (0%) 0% 427.2 505,389 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.36 per share. 23 Feb 2026 2,500 27,697 (0%) 0% 7.4 18,400 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 23 Feb 2026 2,500 0 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 492.42 per share. 26 Jan 2026 647 452,704 (2%) 0% 492.4 318,596 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.46 per share. 26 Jan 2026 4,000 25,197 (0%) 0% 16.5 65,840 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 26 Jan 2026 4,000 0 - - Stock Option (Right to Buy)
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 492.42 per share. 26 Jan 2026 1,577 148,497 (0%) 0% 492.4 776,546 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 494.59 per share. 26 Jan 2026 570 9,122 (0%) 0% 494.6 281,916 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 492.42 per share. 26 Jan 2026 340 9,692 (0%) 0% 492.4 167,423 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 490.77 per share. 20 Jan 2026 2,238 453,351 (2%) 0% 490.8 1,098,343 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 501.40 per share. 20 Jan 2026 429 8,481 (0%) 0% 501.4 215,101 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 490.77 per share. 20 Jan 2026 263 8,910 (0%) 0% 490.8 129,073 Common Stock
Rita Thakkar Chief Accounting Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 15 Jan 2026 2,398 2,398 (0%) 0% 0 Common Stock
Rita Thakkar Chief Accounting Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 15 Jan 2026 1,826 1,826 - - Stock Option (Right to Buy)
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.80 per share. 09 Jan 2026 280 187,444 (1%) 0% 15.8 4,424 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 551.24 per share. 09 Jan 2026 280 187,164 (1%) 0% 551.2 154,348 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 09 Jan 2026 280 0 - - Stock Option (Right to Buy)
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.80 per share. 09 Jan 2026 24,520 211,684 (1%) 0% 15.8 387,416 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 511.98 per share. 09 Jan 2026 1,480 210,204 (1%) 0% 512.0 757,727 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 513.11 per share. 09 Jan 2026 1,094 209,110 (1%) 0% 513.1 561,340 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 514.68 per share. 09 Jan 2026 1,345 207,765 (1%) 0% 514.7 692,246 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 515.81 per share. 09 Jan 2026 1,996 205,769 (1%) 0% 515.8 1,029,561 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 516.84 per share. 09 Jan 2026 766 205,003 (1%) 0% 516.8 395,896 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 517.86 per share. 09 Jan 2026 2,450 202,553 (1%) 0% 517.9 1,268,755 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 518.68 per share. 09 Jan 2026 1,363 201,190 (1%) 0% 518.7 706,966 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 519.88 per share. 09 Jan 2026 846 200,344 (1%) 0% 519.9 439,822 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 521.03 per share. 09 Jan 2026 681 199,663 (1%) 0% 521.0 354,823 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 521.98 per share. 09 Jan 2026 840 198,823 (1%) 0% 522.0 438,461 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 523.00 per share. 09 Jan 2026 970 197,853 (1%) 0% 523.0 507,307 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 524.10 per share. 09 Jan 2026 1,199 196,654 (1%) 0% 524.1 628,394 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 525.05 per share. 09 Jan 2026 2,432 194,222 (1%) 0% 525.0 1,276,916 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 526.00 per share. 09 Jan 2026 1,066 193,156 (1%) 0% 526.0 560,717 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 526.97 per share. 09 Jan 2026 1,560 191,596 (1%) 0% 527.0 822,071 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 528.18 per share. 09 Jan 2026 575 191,021 (1%) 0% 528.2 303,702 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 529.16 per share. 09 Jan 2026 691 190,330 (1%) 0% 529.2 365,653 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 529.77 per share. 09 Jan 2026 166 190,164 (1%) 0% 529.8 87,941 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 530.69 per share. 09 Jan 2026 280 189,884 (1%) 0% 530.7 148,592 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 532.50 per share. 09 Jan 2026 80 189,804 (1%) 0% 532.5 42,600 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 534.16 per share. 09 Jan 2026 332 189,472 (1%) 0% 534.2 177,342 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 535.29 per share. 09 Jan 2026 148 189,324 (1%) 0% 535.3 79,223 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 536.02 per share. 09 Jan 2026 473 188,851 (1%) 0% 536.0 253,538 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 536.88 per share. 09 Jan 2026 487 188,364 (1%) 0% 536.9 261,459 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 537.85 per share. 09 Jan 2026 80 188,284 (1%) 0% 537.9 43,028 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 539.23 per share. 09 Jan 2026 480 187,804 (1%) 0% 539.2 258,831 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 540.36 per share. 09 Jan 2026 600 187,204 (1%) 0% 540.4 324,215 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 545.80 per share. 09 Jan 2026 40 187,164 (1%) 0% 545.8 21,832 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 09 Jan 2026 24,520 280 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.80 per share. 09 Jan 2026 18,410 473,999 (3%) 0% 15.8 290,878 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 09 Jan 2026 240 0 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 512.02 per share. 09 Jan 2026 960 473,039 (3%) 0% 512.0 491,537 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 513.12 per share. 09 Jan 2026 960 472,079 (3%) 0% 513.1 492,595 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 514.63 per share. 09 Jan 2026 937 471,142 (3%) 0% 514.6 482,207 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 515.82 per share. 09 Jan 2026 1,578 469,564 (3%) 0% 515.8 813,968 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 516.81 per share. 09 Jan 2026 521 469,043 (3%) 0% 516.8 269,257 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 517.84 per share. 09 Jan 2026 2,044 466,999 (3%) 0% 517.8 1,058,468 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 518.67 per share. 09 Jan 2026 970 466,029 (3%) 0% 518.7 503,106 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 519.89 per share. 09 Jan 2026 539 465,490 (3%) 0% 519.9 280,220 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 521.11 per share. 09 Jan 2026 440 465,050 (3%) 0% 521.1 229,289 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 521.95 per share. 09 Jan 2026 588 464,462 (3%) 0% 522.0 306,909 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 522.98 per share. 09 Jan 2026 732 463,730 (3%) 0% 523.0 382,823 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 524.06 per share. 09 Jan 2026 1,335 462,395 (2%) 0% 524.1 699,623 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 525.12 per share. 09 Jan 2026 1,489 460,906 (2%) 0% 525.1 781,903 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 526.05 per share. 09 Jan 2026 913 459,993 (2%) 0% 526.0 480,281 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 526.95 per share. 09 Jan 2026 1,135 458,858 (2%) 0% 527.0 598,091 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 528.16 per share. 09 Jan 2026 465 458,393 (2%) 0% 528.2 245,593 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 529.28 per share. 09 Jan 2026 554 457,839 (2%) 0% 529.3 293,222 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 530.45 per share. 09 Jan 2026 256 457,583 (2%) 0% 530.5 135,796 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 531.07 per share. 09 Jan 2026 30 457,553 (2%) 0% 531.1 15,932 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 532.50 per share. 09 Jan 2026 40 457,513 (2%) 0% 532.5 21,300 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 534.17 per share. 09 Jan 2026 271 457,242 (2%) 0% 534.2 144,761 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 534.93 per share. 09 Jan 2026 89 457,153 (2%) 0% 534.9 47,609 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 535.80 per share. 09 Jan 2026 299 456,854 (2%) 0% 535.8 160,205 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 536.88 per share. 09 Jan 2026 385 456,469 (2%) 0% 536.9 206,700 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 537.85 per share. 09 Jan 2026 40 456,429 (2%) 0% 537.9 21,514 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 539.26 per share. 09 Jan 2026 400 456,029 (2%) 0% 539.3 215,706 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 540.25 per share. 09 Jan 2026 40 455,989 (2%) 0% 540.3 21,610 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 542.72 per share. 09 Jan 2026 400 455,589 (2%) 0% 542.7 217,088 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 09 Jan 2026 18,410 240 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.80 per share. 09 Jan 2026 240 455,829 (2%) 0% 15.8 3,792 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 545.80 per share. 09 Jan 2026 40 455,789 (2%) 0% 545.8 21,832 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 551.24 per share. 09 Jan 2026 200 455,589 (2%) 0% 551.2 110,248 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 10 Dec 2025 24,800 24,800 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 555.39 per share. 10 Dec 2025 160 187,164 (1%) 0% 555.4 88,862 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 555.00 per share. 10 Dec 2025 1,029 187,324 (1%) 0% 555.0 571,091 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 553.83 per share. 10 Dec 2025 5,001 188,353 (1%) 0% 553.8 2,769,728 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 552.74 per share. 10 Dec 2025 5,533 193,354 (1%) 0% 552.7 3,058,332 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 551.67 per share. 10 Dec 2025 7,193 198,887 (1%) 0% 551.7 3,968,129 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 550.93 per share. 10 Dec 2025 4,316 206,080 (1%) 0% 550.9 2,377,826 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 549.99 per share. 10 Dec 2025 409 210,396 (1%) 0% 550.0 224,945 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 548.51 per share. 10 Dec 2025 535 210,805 (1%) 0% 548.5 293,451 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 547.75 per share. 10 Dec 2025 624 211,340 (1%) 0% 547.7 341,794 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.80 per share. 10 Dec 2025 24,800 211,964 (1%) 0% 15.8 391,840 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 15.80 per share. 10 Dec 2025 18,650 479,694 (3%) 0% 15.8 294,670 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 547.76 per share. 10 Dec 2025 491 479,203 (3%) 0% 547.8 268,949 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 10 Dec 2025 18,650 18,650 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Gift of securities by or to the insider at price $ 0.00 per share. 10 Dec 2025 5,455 455,589 (2%) 0% 0 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 555.39 per share. 10 Dec 2025 200 461,044 (2%) 0% 555.4 111,078 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 554.84 per share. 10 Dec 2025 1,027 461,244 (2%) 0% 554.8 569,822 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 553.88 per share. 10 Dec 2025 3,087 462,271 (2%) 0% 553.9 1,709,826 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 552.81 per share. 10 Dec 2025 3,857 465,358 (3%) 0% 552.8 2,132,197 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 551.85 per share. 10 Dec 2025 4,410 469,215 (3%) 0% 551.8 2,433,641 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 550.99 per share. 10 Dec 2025 4,723 473,625 (3%) 0% 551.0 2,602,307 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 550.07 per share. 10 Dec 2025 486 478,348 (3%) 0% 550.1 267,335 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 548.56 per share. 10 Dec 2025 369 478,834 (3%) 0% 548.6 202,418 Common Stock
William John Sibold Director, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Dec 2025 50,000 152,474 (0%) 0% - Common Stock
William John Sibold Director, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Dec 2025 50,000 0 - - Performance Restricted Stock Units
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 575.34 per share. 03 Dec 2025 2,400 150,074 (0%) 0% 575.3 1,380,816 Common Stock
Mardi C. Dier EVP and CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 251.63 per share. 02 Dec 2025 4,173 14,613 (0%) 0% 251.6 1,050,052 Common Stock
Mardi C. Dier EVP and CFO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 02 Dec 2025 4,173 9,180 - - Stock Option (Right to Buy)
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 596.19 per share. 02 Dec 2025 80 10,440 (0%) 0% 596.2 47,695 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 595.20 per share. 02 Dec 2025 74 10,520 (0%) 0% 595.2 44,045 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 590.38 per share. 02 Dec 2025 160 10,594 (0%) 0% 590.4 94,460 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 589.65 per share. 02 Dec 2025 160 10,754 (0%) 0% 589.7 94,344 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 587.85 per share. 02 Dec 2025 240 10,914 (0%) 0% 587.9 141,084 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 585.44 per share. 02 Dec 2025 240 11,154 (0%) 0% 585.4 140,505 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 579.85 per share. 02 Dec 2025 480 11,394 (0%) 0% 579.9 278,329 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 578.83 per share. 02 Dec 2025 258 11,874 (0%) 0% 578.8 149,338 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 577.82 per share. 02 Dec 2025 320 12,132 (0%) 0% 577.8 184,901 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 576.15 per share. 02 Dec 2025 240 12,452 (0%) 0% 576.2 138,276 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 574.95 per share. 02 Dec 2025 120 12,692 (0%) 0% 575.0 68,994 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 574.00 per share. 02 Dec 2025 717 12,812 (0%) 0% 574.0 411,559 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 573.01 per share. 02 Dec 2025 354 13,529 (0%) 0% 573.0 202,847 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 571.99 per share. 02 Dec 2025 410 13,883 (0%) 0% 572.0 234,516 Common Stock
Mardi C. Dier EVP and CFO Sale of securities on an exchange or to another person at price $ 570.39 per share. 02 Dec 2025 320 14,293 (0%) 0% 570.4 182,524 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 550.97 per share. 21 Nov 2025 894 11,096 (0%) 0% 551.0 492,567 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 563.20 per share. 21 Nov 2025 40 10,112 (0%) 0% 563.2 22,528 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 560.62 per share. 21 Nov 2025 80 10,152 (0%) 0% 560.6 44,850 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 559.60 per share. 21 Nov 2025 200 10,232 (0%) 0% 559.6 111,920 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 556.04 per share. 21 Nov 2025 120 10,432 (0%) 0% 556.0 66,725 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 553.22 per share. 21 Nov 2025 40 10,552 (0%) 0% 553.2 22,129 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 552.38 per share. 21 Nov 2025 200 10,592 (0%) 0% 552.4 110,477 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 564.56 per share. 21 Nov 2025 80 10,032 (0%) 0% 564.6 45,165 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 549.35 per share. 21 Nov 2025 40 10,792 (0%) 0% 549.4 21,974 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 548.71 per share. 21 Nov 2025 120 10,832 (0%) 0% 548.7 65,845 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 547.27 per share. 21 Nov 2025 144 10,952 (0%) 0% 547.3 78,807 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.36 per share. 13 Nov 2025 2,500 23,697 (0%) 0% 7.4 18,400 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 13 Nov 2025 6,000 4,000 - - Stock Option (Right to Buy)
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 13 Nov 2025 2,500 2,500 - - Stock Option (Right to Buy)
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 530.20 per share. 13 Nov 2025 40 21,197 (0%) 0% 530.2 21,208 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 528.60 per share. 13 Nov 2025 440 21,237 (0%) 0% 528.6 232,586 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 527.85 per share. 13 Nov 2025 200 21,677 (0%) 0% 527.9 105,570 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 526.68 per share. 13 Nov 2025 120 21,877 (0%) 0% 526.7 63,202 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 524.49 per share. 13 Nov 2025 153 21,997 (0%) 0% 524.5 80,247 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 523.66 per share. 13 Nov 2025 811 22,150 (0%) 0% 523.7 424,687 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 522.70 per share. 13 Nov 2025 1,434 22,961 (0%) 0% 522.7 749,557 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 521.79 per share. 13 Nov 2025 1,094 24,395 (0%) 0% 521.8 570,836 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 520.68 per share. 13 Nov 2025 308 25,489 (0%) 0% 520.7 160,369 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 519.67 per share. 13 Nov 2025 1,355 25,797 (0%) 0% 519.7 704,147 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 518.53 per share. 13 Nov 2025 835 27,152 (0%) 0% 518.5 432,974 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 517.51 per share. 13 Nov 2025 645 27,987 (0%) 0% 517.5 333,796 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 515.64 per share. 13 Nov 2025 919 28,632 (0%) 0% 515.6 473,876 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 514.67 per share. 13 Nov 2025 146 29,551 (0%) 0% 514.7 75,142 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 16.46 per share. 13 Nov 2025 6,000 29,697 (0%) 0% 16.5 98,760 Common Stock
Kenneth M. Bate Director 05 Nov 2025 5,470 8,097 (0%) 0% 9.5 51,692 Common Stock
Kenneth M. Bate Director 05 Nov 2025 1,105 0 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 05 Nov 2025 10,000 0 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 05 Nov 2025 5,470 0 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 05 Nov 2025 30 2,627 (0%) 0% 491.0 14,729 Common Stock
Kenneth M. Bate Director 05 Nov 2025 933 2,657 (0%) 0% 489.9 457,119 Common Stock
Kenneth M. Bate Director 05 Nov 2025 696 3,590 (0%) 0% 489.1 340,409 Common Stock
Kenneth M. Bate Director 05 Nov 2025 2,775 4,286 (0%) 0% 487.5 1,352,796 Common Stock
Kenneth M. Bate Director 05 Nov 2025 827 7,061 (0%) 0% 486.7 402,530 Common Stock
Kenneth M. Bate Director 05 Nov 2025 1,008 7,888 (0%) 0% 485.5 489,421 Common Stock
Kenneth M. Bate Director 05 Nov 2025 1,931 8,896 (0%) 0% 484.8 936,105 Common Stock
Kenneth M. Bate Director 05 Nov 2025 2,069 10,827 (0%) 0% 483.4 1,000,170 Common Stock
Kenneth M. Bate Director 05 Nov 2025 1,284 12,896 (0%) 0% 482.4 619,417 Common Stock
Kenneth M. Bate Director 05 Nov 2025 3,259 14,180 (0%) 0% 481.1 1,567,995 Common Stock
Kenneth M. Bate Director 05 Nov 2025 1,763 17,439 (0%) 0% 480.2 846,663 Common Stock
Kenneth M. Bate Director 05 Nov 2025 1,105 19,202 (0%) 0% 280.0 309,444 Common Stock
Kenneth M. Bate Director 05 Nov 2025 10,000 18,097 (0%) 0% 303.8 3,037,900 Common Stock
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 445.63 per share. 09 Sep 2025 7,279 102,474 (0%) 0% 445.6 3,243,741 Common Stock
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 400.03 per share. 21 Aug 2025 6,485 110,884 (0%) 0% 400.0 2,594,225 Common Stock
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 401.00 per share. 21 Aug 2025 1,131 109,753 (0%) 0% 401 453,531 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 358.66 per share. 18 Aug 2025 458 10,019 (0%) 0% 358.7 164,266 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 376.62 per share. 18 Aug 2025 42 9,173 (0%) 0% 376.6 15,818 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 375.75 per share. 18 Aug 2025 190 9,215 (0%) 0% 375.8 71,393 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 374.13 per share. 18 Aug 2025 68 9,405 (0%) 0% 374.1 25,441 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 372.44 per share. 18 Aug 2025 252 9,473 (0%) 0% 372.4 93,855 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 371.35 per share. 18 Aug 2025 84 9,725 (0%) 0% 371.3 31,193 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 370.06 per share. 18 Aug 2025 84 9,809 (0%) 0% 370.1 31,085 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 369.64 per share. 18 Aug 2025 126 9,893 (0%) 0% 369.6 46,575 Common Stock
Kenneth M. Bate Director 15 Aug 2025 10,000 12,627 (0%) 0% 16.5 164,600 Common Stock
Kenneth M. Bate Director 15 Aug 2025 10,000 0 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 15 Aug 2025 896 2,627 (0%) 0% 368.6 330,226 Common Stock
Kenneth M. Bate Director 15 Aug 2025 1,104 3,523 (0%) 0% 367.6 405,865 Common Stock
Kenneth M. Bate Director 15 Aug 2025 600 4,627 (0%) 0% 366.1 219,683 Common Stock
Kenneth M. Bate Director 15 Aug 2025 2,567 5,227 (0%) 0% 365.3 937,793 Common Stock
Kenneth M. Bate Director 15 Aug 2025 2,516 7,794 (0%) 0% 364.2 916,428 Common Stock
Kenneth M. Bate Director 15 Aug 2025 2,317 10,310 (0%) 0% 363.4 842,014 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 13 Aug 2025 129,172 316,336 (2%) 0% 9.4 1,220,675 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 13 Aug 2025 129,172 0 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 374.38 per share. 13 Aug 2025 4,155 187,164 (1%) 0% 374.4 1,555,563 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 373.35 per share. 13 Aug 2025 24,166 191,319 (1%) 0% 373.3 9,022,330 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 372.39 per share. 13 Aug 2025 28,976 215,485 (1%) 0% 372.4 10,790,486 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 371.53 per share. 13 Aug 2025 22,710 244,461 (1%) 0% 371.5 8,437,340 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 370.44 per share. 13 Aug 2025 7,877 267,171 (1%) 0% 370.4 2,917,943 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 369.44 per share. 13 Aug 2025 7,992 275,048 (1%) 0% 369.4 2,952,555 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 368.34 per share. 13 Aug 2025 6,788 283,040 (1%) 0% 368.3 2,500,325 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 367.31 per share. 13 Aug 2025 7,119 289,828 (1%) 0% 367.3 2,614,888 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 366.22 per share. 13 Aug 2025 3,152 296,947 (1%) 0% 366.2 1,154,330 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 365.19 per share. 13 Aug 2025 1,716 300,099 (1%) 0% 365.2 626,671 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 364.02 per share. 13 Aug 2025 3,529 301,815 (1%) 0% 364.0 1,284,639 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 363.08 per share. 13 Aug 2025 2,591 305,344 (1%) 0% 363.1 940,731 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 362.29 per share. 13 Aug 2025 1,439 307,935 (1%) 0% 362.3 521,332 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 361.13 per share. 13 Aug 2025 1,754 309,374 (2%) 0% 361.1 633,424 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 360.27 per share. 13 Aug 2025 3,153 311,128 (2%) 0% 360.3 1,135,938 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 359.31 per share. 13 Aug 2025 455 314,281 (2%) 0% 359.3 163,485 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 358.23 per share. 13 Aug 2025 1,600 314,736 (2%) 0% 358.2 573,171 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 350.19 per share. 11 Aug 2025 2,903 187,464 (1%) 0% 350.2 1,016,605 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 Aug 2025 43,605 129,172 - - Stock Option (Right to Buy)
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 Aug 2025 3,203 172,777 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 359.81 per share. 11 Aug 2025 600 187,164 (1%) 0% 359.8 215,886 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 358.83 per share. 11 Aug 2025 5,032 187,764 (1%) 0% 358.8 1,805,615 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 357.93 per share. 11 Aug 2025 8,434 192,796 (1%) 0% 357.9 3,018,786 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 356.94 per share. 11 Aug 2025 5,094 201,230 (1%) 0% 356.9 1,818,251 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 355.97 per share. 11 Aug 2025 5,244 206,324 (1%) 0% 356.0 1,866,710 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 355.00 per share. 11 Aug 2025 6,546 211,568 (1%) 0% 355.0 2,323,856 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 354.06 per share. 11 Aug 2025 4,768 218,114 (1%) 0% 354.1 1,688,137 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 352.61 per share. 11 Aug 2025 1,382 222,882 (1%) 0% 352.6 487,309 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 351.59 per share. 11 Aug 2025 3,202 224,264 (1%) 0% 351.6 1,125,806 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 350.93 per share. 11 Aug 2025 3,303 227,466 (1%) 0% 350.9 1,159,113 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 11 Aug 2025 43,605 230,769 (1%) 0% 9.4 412,067 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 351.04 per share. 11 Aug 2025 300 187,164 (1%) 0% 351.0 105,312 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 11 Aug 2025 3,203 190,367 (1%) 0% 9.4 30,268 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 Aug 2025 43,263 0 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 11 Aug 2025 3,200 43,263 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 359.71 per share. 11 Aug 2025 700 461,044 (2%) 0% 359.7 251,798 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 358.81 per share. 11 Aug 2025 6,541 461,744 (2%) 0% 358.8 2,346,983 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 357.85 per share. 11 Aug 2025 6,715 468,285 (3%) 0% 357.9 2,402,982 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 356.88 per share. 11 Aug 2025 4,864 475,000 (3%) 0% 356.9 1,735,861 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 355.95 per share. 11 Aug 2025 5,752 479,864 (3%) 0% 356.0 2,047,436 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 354.97 per share. 11 Aug 2025 6,479 485,616 (3%) 0% 355.0 2,299,873 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 354.04 per share. 11 Aug 2025 4,587 492,095 (3%) 0% 354.0 1,623,997 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 352.45 per share. 11 Aug 2025 1,175 496,682 (3%) 0% 352.5 414,130 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 351.60 per share. 11 Aug 2025 2,870 497,857 (3%) 0% 351.6 1,009,091 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 350.87 per share. 11 Aug 2025 3,580 500,727 (3%) 0% 350.9 1,256,127 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 11 Aug 2025 43,263 504,307 (3%) 0% 9.4 408,835 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 351.02 per share. 11 Aug 2025 220 461,044 (2%) 0% 351.0 77,225 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 350.18 per share. 11 Aug 2025 2,980 461,264 (2%) 0% 350.2 1,043,528 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 11 Aug 2025 3,200 464,244 (3%) 0% 9.5 30,240 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 18 Jul 2025 1,400 175,980 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 350.00 per share. 18 Jul 2025 1,000 461,044 (2%) 0% 350.0 350,005 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 18 Jul 2025 1,000 462,044 (2%) 0% 9.5 9,450 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 18 Jul 2025 1,000 46,463 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 350.03 per share. 18 Jul 2025 1,400 187,164 (1%) 0% 350.0 490,044 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 18 Jul 2025 1,400 188,564 (1%) 0% 9.5 13,230 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 16 Jul 2025 26,176 213,340 (1%) 0% 9.4 247,363 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 16 Jul 2025 26,176 180,080 - - Stock Option (Right to Buy)
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 16 Jul 2025 2,700 177,380 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 351.57 per share. 16 Jul 2025 700 187,164 (1%) 0% 351.6 246,098 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 350.10 per share. 16 Jul 2025 2,000 187,864 (1%) 0% 350.1 700,203 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 16 Jul 2025 2,700 189,864 (1%) 0% 9.5 25,515 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 356.62 per share. 16 Jul 2025 1,200 187,164 (1%) 0% 356.6 427,941 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 355.61 per share. 16 Jul 2025 5,784 188,364 (1%) 0% 355.6 2,056,860 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 354.65 per share. 16 Jul 2025 6,851 194,148 (1%) 0% 354.6 2,429,697 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 353.82 per share. 16 Jul 2025 2,319 200,999 (1%) 0% 353.8 820,507 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 352.67 per share. 16 Jul 2025 2,110 203,318 (1%) 0% 352.7 744,133 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 351.38 per share. 16 Jul 2025 2,371 205,428 (1%) 0% 351.4 833,131 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 350.17 per share. 16 Jul 2025 5,541 207,799 (1%) 0% 350.2 1,940,275 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 350.19 per share. 16 Jul 2025 6,000 481,488 (3%) 0% 350.2 2,101,142 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 16 Jul 2025 2,657 47,463 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 16 Jul 2025 26,444 50,120 - - Stock Option (Right to Buy)
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 351.50 per share. 16 Jul 2025 600 461,044 (2%) 0% 351.5 210,898 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 350.09 per share. 16 Jul 2025 2,057 461,644 (2%) 0% 350.1 720,137 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 16 Jul 2025 2,657 463,701 (3%) 0% 9.5 25,109 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 356.52 per share. 16 Jul 2025 1,380 461,044 (2%) 0% 356.5 492,004 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 355.61 per share. 16 Jul 2025 6,441 462,424 (2%) 0% 355.6 2,290,499 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 354.61 per share. 16 Jul 2025 5,800 468,865 (3%) 0% 354.6 2,056,738 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 353.82 per share. 16 Jul 2025 2,569 474,665 (3%) 0% 353.8 908,963 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 352.64 per share. 16 Jul 2025 2,357 477,234 (3%) 0% 352.6 831,170 Common Stock
Rebecca A. Taub Director Sale of securities on an exchange or to another person at price $ 351.37 per share. 16 Jul 2025 1,897 479,591 (3%) 0% 351.4 666,546 Common Stock
Rebecca A. Taub Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 16 Jul 2025 26,444 487,488 (3%) 0% 9.5 249,896 Common Stock
Paul A. Friedman Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 715 187,164 (1%) 0% 0 Common Stock
Paul A. Friedman Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 1,290 1,290 - - Stock Option (Right to Buy)
Jacqualyn A. Fouse Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 366 366 - - Stock Option (Right to Buy)
Jacqualyn A. Fouse Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 203 1,097 (0%) 0% 0 Common Stock
Kenneth M. Bate Director 20 Jun 2025 715 2,627 (0%) 0% 0 Common Stock
Kenneth M. Bate Director 20 Jun 2025 1,290 1,290 - - Stock Option (Right to Buy)
Richard S. Levy Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 1,290 1,290 - - Stock Option (Right to Buy)
Richard S. Levy Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 715 21,197 (0%) 0% 0 Common Stock
James M. Daly Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 1,290 1,290 - - Stock Option (Right to Buy)
James M. Daly Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 20 Jun 2025 715 2,627 (0%) 0% 0 Common Stock
David Soergel Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 15 May 2025 7,545 7,545 (0%) 0% 0 Common Stock
David Soergel Chief Medical Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 15 May 2025 12,839 12,839 - - Stock Option (Right to Buy)
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.06 per share. 10 Apr 2025 9,470 20,482 (0%) 0% 65.1 616,118 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 10 Apr 2025 9,470 0 - - Stock Option (Right to Buy)
Frederick B. Craves Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.06 per share. 12 Mar 2025 1,728 351,804 (2%) 0% 65.1 112,424 Common Stock
Frederick B. Craves Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 12 Mar 2025 7,742 0 - - Stock Option (Right to Buy)
Frederick B. Craves Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 12 Mar 2025 6,000 0 - - Stock Option (Right to Buy)
Frederick B. Craves Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 12 Mar 2025 1,728 7,742 - - Stock Option (Right to Buy)
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 330.23 per share. 12 Mar 2025 75 350,076 (2%) 0% 330.2 24,767 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 329.86 per share. 12 Mar 2025 967 350,151 (2%) 0% 329.9 318,975 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 328.68 per share. 12 Mar 2025 400 351,118 (2%) 0% 328.7 131,472 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 327.63 per share. 12 Mar 2025 1,000 351,518 (2%) 0% 327.6 327,627 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 325.63 per share. 12 Mar 2025 800 352,518 (2%) 0% 325.6 260,501 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 324.69 per share. 12 Mar 2025 900 353,318 (2%) 0% 324.7 292,218 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 323.47 per share. 12 Mar 2025 1,649 354,218 (2%) 0% 323.5 533,394 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 322.45 per share. 12 Mar 2025 1,951 355,867 (2%) 0% 322.5 629,100 Common Stock
Frederick B. Craves Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.06 per share. 12 Mar 2025 7,742 357,818 (2%) 0% 65.1 503,695 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 334.97 per share. 12 Mar 2025 200 350,076 (2%) 0% 335.0 66,994 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 333.66 per share. 12 Mar 2025 800 350,276 (2%) 0% 333.7 266,926 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 332.38 per share. 12 Mar 2025 2,382 351,076 (2%) 0% 332.4 791,726 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 331.36 per share. 12 Mar 2025 2,759 353,458 (2%) 0% 331.4 914,221 Common Stock
Frederick B. Craves Director Sale of securities on an exchange or to another person at price $ 330.54 per share. 12 Mar 2025 1,587 356,217 (2%) 0% 330.5 524,560 Common Stock
Frederick B. Craves Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 111.06 per share. 12 Mar 2025 6,000 357,804 (2%) 0% 111.1 666,360 Common Stock
Jacqualyn A. Fouse Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 10 Mar 2025 894 894 (0%) 0% 0 Common Stock
Jacqualyn A. Fouse Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 10 Mar 2025 1,579 1,579 - - Stock Option (Right to Buy)
Mardi C. Dier SVP and CFO Sale of securities on an exchange or to another person at price $ 323.04 per share. 10 Mar 2025 258 10,440 (0%) 0% 323.0 83,344 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 4,382 461,044 (2%) 0% 0 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 7,381 7,381 - - Stock Option (Right to Buy)
William John Sibold Director, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 22,009 22,009 - - Stock Option (Right to Buy)
William John Sibold Director, President and CEO Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 13,066 117,369 (0%) 0% 0 Common Stock
Mardi C. Dier SVP and CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 6,374 6,374 - - Stock Option (Right to Buy)
Mardi C. Dier SVP and CFO Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 3,784 10,698 (0%) 0% 0 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 344.76 per share. 05 Mar 2025 1,412 3,728 (0%) 0% 344.8 486,797 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 343.85 per share. 05 Mar 2025 4,701 5,140 (0%) 0% 343.8 1,616,429 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 342.90 per share. 05 Mar 2025 1,077 9,841 (0%) 0% 342.9 369,300 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 341.84 per share. 05 Mar 2025 1,043 10,918 (0%) 0% 341.8 356,537 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 340.75 per share. 05 Mar 2025 1,657 11,961 (0%) 0% 340.8 564,627 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 1,157 1,157 - - Stock Option (Right to Buy)
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 338.09 per share. 05 Mar 2025 1,146 14,018 (0%) 0% 338.1 387,452 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 336.78 per share. 05 Mar 2025 1,777 15,164 (0%) 0% 336.8 598,457 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 335.15 per share. 05 Mar 2025 900 16,941 (0%) 0% 335.1 301,631 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Exercise or conversion of derivative security received from the company (such as an option) at price $ 87.09 per share. 05 Mar 2025 7,288 17,841 (0%) 0% 87.1 634,712 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Exercise or conversion of derivative security received from the company (such as an option) at price $ 87.92 per share. 05 Mar 2025 6,825 10,553 (0%) 0% 87.9 600,054 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 339.68 per share. 05 Mar 2025 400 13,618 (0%) 0% 339.7 135,874 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Mar 2025 7,288 3,062 - - Stock Option (Right to Buy)
Robert E. Waltermire Senior VP, Chief Pharma Dev. Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 05 Mar 2025 6,825 4,375 - - Stock Option (Right to Buy)
Robert E. Waltermire Senior VP, Chief Pharma Dev. Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 2,061 5,789 (0%) 0% 0 Common Stock
Carole Huntsman Chief Commercial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 5,703 5,703 - - Stock Option (Right to Buy)
Carole Huntsman Chief Commercial Officer Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 3,386 11,990 (0%) 0% 0 Common Stock
Shannon T. Kelley General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 3,187 10,477 (0%) 0% 0 Common Stock
Shannon T. Kelley General Counsel Grant, award, or other acquisition of securities at price $ 0.00 per share. 05 Mar 2025 5,368 5,368 - - Stock Option (Right to Buy)
Mardi C. Dier SVP and CFO Sale of securities on an exchange or to another person at price $ 323.54 per share. 03 Mar 2025 774 6,914 (0%) 0% 323.5 250,417 Common Stock
Mardi C. Dier SVP and CFO Sale of securities on an exchange or to another person at price $ 325.89 per share. 03 Mar 2025 1,187 7,688 (0%) 0% 325.9 386,831 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 314.74 per share. 03 Mar 2025 200 10,167 (0%) 0% 314.7 62,948 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 313.08 per share. 03 Mar 2025 71 10,367 (0%) 0% 313.1 22,229 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 335.00 per share. 03 Mar 2025 563 8,604 (0%) 0% 335 188,605 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 329.64 per share. 03 Mar 2025 100 9,167 (0%) 0% 329.6 32,964 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 327.49 per share. 03 Mar 2025 100 9,267 (0%) 0% 327.5 32,749 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 326.34 per share. 03 Mar 2025 100 9,367 (0%) 0% 326.3 32,634 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 324.59 per share. 03 Mar 2025 200 9,467 (0%) 0% 324.6 64,918 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 323.65 per share. 03 Mar 2025 200 9,667 (0%) 0% 323.7 64,730 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 320.21 per share. 03 Mar 2025 300 9,867 (0%) 0% 320.2 96,063 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 335.00 per share. 03 Mar 2025 415 7,290 (0%) 0% 335 139,025 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 340.99 per share. 28 Feb 2025 1,052 3,903 (0%) 0% 341.0 358,717 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 341.55 per share. 28 Feb 2025 175 3,728 (0%) 0% 341.5 59,771 Common Stock
Kenneth M. Bate Director 27 Feb 2025 8,545 12,529 (0%) 0% 355.1 3,034,150 Common Stock
Kenneth M. Bate Director 27 Feb 2025 6,000 7,912 (0%) 0% 111.1 666,360 Common Stock
Kenneth M. Bate Director 27 Feb 2025 9,470 17,382 (0%) 0% 65.1 616,118 Common Stock
Kenneth M. Bate Director 27 Feb 2025 4,530 21,912 (0%) 0% 9.5 42,809 Common Stock
Kenneth M. Bate Director 27 Feb 2025 100 21,812 (0%) 0% 351.0 35,101 Common Stock
Kenneth M. Bate Director 27 Feb 2025 500 21,312 (0%) 0% 352.0 175,995 Common Stock
Kenneth M. Bate Director 27 Feb 2025 238 21,074 (0%) 0% 353.8 84,213 Common Stock
Kenneth M. Bate Director 27 Feb 2025 2,038 7,700 (0%) 0% 357.3 728,109 Common Stock
Kenneth M. Bate Director 27 Feb 2025 2,791 9,738 (0%) 0% 356.5 995,016 Common Stock
Kenneth M. Bate Director 27 Feb 2025 2,024 2,128 (0%) 0% 359.2 727,042 Common Stock
Kenneth M. Bate Director 27 Feb 2025 3,548 4,152 (0%) 0% 358.3 1,271,359 Common Stock
Kenneth M. Bate Director 27 Feb 2025 4,530 5,470 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 27 Feb 2025 9,470 0 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 27 Feb 2025 6,000 0 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 27 Feb 2025 216 1,912 (0%) 0% 360.1 77,774 Common Stock
William John Sibold Director, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 27 Feb 2025 50,000 104,303 (0%) 0% - Common Stock
William John Sibold Director, President and CEO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 27 Feb 2025 50,000 0 - - Performance Restricted Stock Units
James M. Daly Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 27 Feb 2025 9,470 0 - - Stock Option (Right to Buy)
James M. Daly Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 65.06 per share. 27 Feb 2025 9,470 11,382 (0%) 0% 65.1 616,118 Common Stock
James M. Daly Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 111.06 per share. 27 Feb 2025 6,000 17,382 (0%) 0% 111.1 666,360 Common Stock
James M. Daly Director Sale of securities on an exchange or to another person at price $ 346.90 per share. 27 Feb 2025 398 16,984 (0%) 0% 346.9 138,067 Common Stock
James M. Daly Director Sale of securities on an exchange or to another person at price $ 347.39 per share. 27 Feb 2025 14,302 2,682 (0%) 0% 347.4 4,968,372 Common Stock
James M. Daly Director Sale of securities on an exchange or to another person at price $ 348.94 per share. 27 Feb 2025 770 1,912 (0%) 0% 348.9 268,686 Common Stock
James M. Daly Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 27 Feb 2025 6,000 0 - - Stock Option (Right to Buy)
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 335.24 per share. 24 Jan 2025 648 456,662 (2%) 0% 335.2 217,236 Common Stock
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 335.24 per share. 24 Jan 2025 1,584 54,303 (0%) 0% 335.2 531,020 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 335.24 per share. 24 Jan 2025 103 4,955 (0%) 0% 335.2 34,530 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 335.24 per share. 24 Jan 2025 347 10,438 (0%) 0% 335.2 116,328 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 273.41 per share. 17 Jan 2025 1,689 457,310 (2%) 0% 273.4 461,789 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. Sale of securities on an exchange or to another person at price $ 273.41 per share. 17 Jan 2025 442 5,058 (0%) 0% 273.4 120,847 Common Stock
Shannon T. Kelley General Counsel Sale of securities on an exchange or to another person at price $ 273.41 per share. 17 Jan 2025 277 7,705 (0%) 0% 273.4 75,735 Common Stock
Craves Frederick B. Director 03 Dec 2024 3,080 11,520 (0%) 0% 315.2 970,852 Common Stock
Craves B. Frederick Director 03 Dec 2024 520 11,000 (0%) 0% 315.9 164,270 Common Stock
Craves B. Frederick Director 25 Nov 2024 1,200 14,600 (0%) 0% 350.7 420,858 Common Stock
B. Craves Frederick Director 25 Nov 2024 2,200 15,800 (0%) 0% 350.1 770,171 Common Stock
Carole Huntsman Chief Commercial Officer Sale of securities on an exchange or to another person at price $ 316.92 per share. 21 Nov 2024 688 10,785 (0%) 0% 316.9 218,041 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.36 per share. 07 Nov 2024 5,000 16,012 (0%) 0% 7.4 36,800 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 07 Nov 2024 5,000 5,000 - - Stock Option (Right to Buy)
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 350.00 per share. 07 Nov 2024 5,000 11,012 (0%) 0% 350 1,750,000 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 7.36 per share. 01 Nov 2024 5,000 16,012 (0%) 0% 7.4 36,800 Common Stock
Richard S. Levy Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 01 Nov 2024 5,000 10,000 - - Stock Option (Right to Buy)
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 304.29 per share. 01 Nov 2024 300 11,012 (0%) 0% 304.3 91,287 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 302.25 per share. 01 Nov 2024 800 11,312 (0%) 0% 302.2 241,799 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 301.22 per share. 01 Nov 2024 1,100 12,112 (0%) 0% 301.2 331,339 Common Stock
Richard S. Levy Director Sale of securities on an exchange or to another person at price $ 300.10 per share. 01 Nov 2024 2,800 13,212 (0%) 0% 300.1 840,278 Common Stock
Frederick B. Craves Director 13 Sep 2024 15,000 360,076 (2%) 0% 0 Common Stock
William John Sibold Director, President and CEO Sale of securities on an exchange or to another person at price $ 243.83 per share. 09 Sep 2024 6,363 55,887 (0%) 0% 243.8 1,551,490 Common Stock
Shannon T. Kelley General Counsel 15 Aug 2024 5,215 7,982 (0%) 0% 0 Common Stock
Shannon T. Kelley General Counsel 15 Aug 2024 7,820 7,820 - - Stock Option (Right to Buy)
Paul A. Friedman Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 25 Jun 2024 714 186,449 (1%) 0% 0 Common Stock
Paul A. Friedman Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 25 Jun 2024 1,105 1,105 - - Stock Option (Right to Buy)
Frederick B. Craves Director 25 Jun 2024 714 375,076 (2%) 0% 0 Common Stock
Frederick B. Craves Director 25 Jun 2024 1,105 1,105 - - Stock Option (Right to Buy)
Kenneth M. Bate Director 25 Jun 2024 714 1,912 (0%) 0% 0 Common Stock
Kenneth M. Bate Director 25 Jun 2024 1,105 1,105 - - Stock Option (Right to Buy)
Richard S. Levy Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 25 Jun 2024 714 11,012 (0%) 0% 0 Common Stock
Richard S. Levy Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 25 Jun 2024 1,105 1,105 - - Stock Option (Right to Buy)
James M. Daly Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 25 Jun 2024 1,105 1,105 - - Stock Option (Right to Buy)
James M. Daly Director Grant, award, or other acquisition of securities at price $ 0.00 per share. 25 Jun 2024 714 1,912 (0%) 0% 0 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. 14 Jun 2024 1,900 10,350 - - Stock Option (Right to Buy)
Robert E. Waltermire Senior VP, Chief Pharma Dev. 14 Jun 2024 1,900 7,400 (0%) 0% 87.1 165,471 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. 14 Jun 2024 1,900 5,500 (0%) 0% 280 532,000 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. 12 Jun 2024 2,000 15,200 - - Stock Option (Right to Buy)
Robert E. Waltermire Senior VP, Chief Pharma Dev. 12 Jun 2024 2,000 5,500 (0%) 0% 285 570,000 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. 12 Jun 2024 2,000 7,500 (0%) 0% 87.9 175,840 Common Stock
Frederick B. Craves Director 11 Jun 2024 39,000 374,362 (2%) 0% 0 Common Stock
Frederick B. Craves Director 11 Jun 2024 45,852 11,210 (0%) 0% 0 Common Stock
Robert E. Waltermire Senior VP, Chief Pharma Dev. 21 May 2024 1,036 5,500 (0%) 0% 231.3 239,668 Common Stock
Frederick B. Craves Director 14 May 2024 1,100 414,462 (2%) 0% 217.9 239,641 Common Stock
Frederick B. Craves Director 14 May 2024 8,827 427,024 (2%) 0% 211.0 1,862,432 Common Stock
Frederick B. Craves Director 14 May 2024 12,489 435,851 (2%) 0% 105.1 1,312,344 Common Stock
Frederick B. Craves Director 14 May 2024 10,000 423,362 (2%) 0% 100.5 1,004,500 Common Stock
Frederick B. Craves Director 14 May 2024 12,489 0 - - Stock Option (right to buy)
Frederick B. Craves Director 14 May 2024 10,000 0 - - Stock Option (right to buy)
Frederick B. Craves Director 14 May 2024 100 413,362 (2%) 0% 219.9 21,990 Common Stock
Frederick B. Craves Director 14 May 2024 1,000 413,462 (2%) 0% 219.0 218,995 Common Stock
Frederick B. Craves Director 14 May 2024 721 415,562 (2%) 0% 217.0 156,445 Common Stock
Frederick B. Craves Director 14 May 2024 375 416,283 (2%) 0% 216.1 81,031 Common Stock
Frederick B. Craves Director 14 May 2024 1,804 416,658 (2%) 0% 214.7 387,285 Common Stock
Frederick B. Craves Director 14 May 2024 2,190 418,462 (2%) 0% 213.9 468,342 Common Stock
Frederick B. Craves Director 14 May 2024 1,363 420,652 (2%) 0% 212.9 290,116 Common Stock
Frederick B. Craves Director 14 May 2024 5,009 422,015 (2%) 0% 211.8 1,061,127 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 244.12 per share. 08 Apr 2024 3,730 206,834 (1%) 0% 244.1 910,566 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 242.95 per share. 08 Apr 2024 1,441 210,564 (1%) 0% 243.0 350,094 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 08 Apr 2024 26,270 212,005 (1%) 0% 9.5 248,252 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 248.59 per share. 08 Apr 2024 4,866 185,735 (1%) 0% 248.6 1,209,642 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 247.76 per share. 08 Apr 2024 3,464 190,601 (1%) 0% 247.8 858,241 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 246.96 per share. 08 Apr 2024 5,028 194,065 (1%) 0% 247.0 1,241,710 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 245.71 per share. 08 Apr 2024 2,078 199,093 (1%) 0% 245.7 510,591 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 08 Apr 2024 26,270 206,256 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 244.86 per share. 08 Apr 2024 5,663 201,171 (1%) 0% 244.9 1,386,646 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 08 Apr 2024 2,676 461,675 (2%) 0% 9.4 25,288 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 244.79 per share. 08 Apr 2024 945 460,506 (2%) 0% 244.8 231,325 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 245.69 per share. 08 Apr 2024 300 460,206 (2%) 0% 245.7 73,706 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 246.98 per share. 08 Apr 2024 600 459,606 (2%) 0% 247.0 148,186 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 247.76 per share. 08 Apr 2024 407 459,199 (2%) 0% 247.8 100,838 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 248.58 per share. 08 Apr 2024 200 458,999 (2%) 0% 248.6 49,716 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 08 Apr 2024 2,676 76,564 - - Stock Option (Right to Buy)
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 243.25 per share. 08 Apr 2024 224 461,451 (2%) 0% 243.2 54,487 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 03 Apr 2024 27,613 213,348 (1%) 0% 9.5 260,943 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Apr 2024 27,613 232,526 - - Stock Option (Right to Buy)
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Apr 2024 18,710 260,139 - - Stock Option (Right to Buy)
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Apr 2024 27,407 278,849 - - Stock Option (Right to Buy)
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 245.92 per share. 03 Apr 2024 444 185,735 (1%) 0% 245.9 109,189 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 245.35 per share. 03 Apr 2024 5,228 186,179 (1%) 0% 245.3 1,282,669 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 244.22 per share. 03 Apr 2024 3,966 191,407 (1%) 0% 244.2 968,588 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 243.20 per share. 03 Apr 2024 9,264 195,373 (1%) 0% 243.2 2,253,016 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 242.42 per share. 03 Apr 2024 6,679 204,637 (1%) 0% 242.4 1,619,098 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 241.15 per share. 03 Apr 2024 612 211,316 (1%) 0% 241.1 147,582 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 240.10 per share. 03 Apr 2024 1,420 211,928 (1%) 0% 240.1 340,939 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 248.42 per share. 03 Apr 2024 200 185,735 (1%) 0% 248.4 49,685 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 247.14 per share. 03 Apr 2024 737 185,935 (1%) 0% 247.1 182,141 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 246.13 per share. 03 Apr 2024 1,558 186,672 (1%) 0% 246.1 383,471 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 245.14 per share. 03 Apr 2024 2,549 188,230 (1%) 0% 245.1 624,857 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 244.31 per share. 03 Apr 2024 627 190,779 (1%) 0% 244.3 153,185 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 243.00 per share. 03 Apr 2024 1,467 191,406 (1%) 0% 243.0 356,482 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 242.25 per share. 03 Apr 2024 5,299 192,873 (1%) 0% 242.2 1,283,679 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 241.07 per share. 03 Apr 2024 6,273 198,172 (1%) 0% 241.1 1,512,222 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 03 Apr 2024 18,710 204,445 (1%) 0% 9.5 176,810 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 246.31 per share. 03 Apr 2024 1,821 185,735 (1%) 0% 246.3 448,530 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 245.34 per share. 03 Apr 2024 18,806 187,556 (1%) 0% 245.3 4,613,823 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 244.58 per share. 03 Apr 2024 4,301 206,362 (1%) 0% 244.6 1,051,959 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 243.64 per share. 03 Apr 2024 2,294 210,663 (1%) 0% 243.6 558,921 Common Stock
Paul A. Friedman Director Sale of securities on an exchange or to another person at price $ 242.00 per share. 03 Apr 2024 185 212,957 (1%) 0% 242 44,770 Common Stock
Paul A. Friedman Director Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.45 per share. 03 Apr 2024 27,407 213,142 (1%) 0% 9.4 258,996 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Sale of securities on an exchange or to another person at price $ 242.00 per share. 03 Apr 2024 135 486,709 (3%) 0% 242 32,670 Common Stock
Rebecca A. Taub Director, Pres., R&D, and CMO Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. 03 Apr 2024 27,506 79,240 - - Stock Option (Right to Buy)
*All Values are in $ Million
Client Category: Promoter/ KMP/ Director / Immediate Relatives / Employee / etc  
Security Type: Share/ Warrants / Convertible Debentures
Data as reported to USA Exchanges
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Screeners based on Insider Trading and SAST parameters