XNAS 04 May, 2026 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Yang Li | Exec. Vice President, Research | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Mar 2026 | 1,666 | 14,425 | - | 0 | Common Stock | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2026 | 242,200 | 242,200 | - | - | Employee Stock Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2026 | 242,200 | 242,200 | - | - | Restricted Stock Unit | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2026 | 100,950 | 100,950 | - | - | Employee Stock Option (right to buy) | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Feb 2026 | 100,950 | 100,950 | - | - | Restricted Stock Unit | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.89 per share. | 15 Jan 2026 | 5,590 | 890,604 | - | 19.9 | 111,180 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.60 per share. | 15 Jan 2026 | 9,568 | 1,016,658 | - | 19.6 | 187,532 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.60 per share. | 15 Jan 2026 | 8,484 | 900,292 | - | 19.6 | 166,286 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 15 Jan 2026 | 1,358 | 1,007,090 | - | 20 | 27,160 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 15 Jan 2026 | 1,204 | 891,808 | - | 20 | 24,080 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.89 per share. | 15 Jan 2026 | 6,303 | 1,005,732 | - | 19.9 | 125,360 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.80 per share. | 13 Jan 2026 | 5,861 | 882,418 | - | 19.8 | 116,072 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.99 per share. | 13 Jan 2026 | 2,927 | 999,429 | - | 20.0 | 58,506 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.99 per share. | 13 Jan 2026 | 2,596 | 885,014 | - | 20.0 | 51,890 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.80 per share. | 13 Jan 2026 | 6,609 | 996,502 | - | 19.8 | 130,885 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.89 per share. | 06 Jan 2026 | 7,097 | 876,557 | - | 19.9 | 141,139 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.89 per share. | 06 Jan 2026 | 8,003 | 989,893 | - | 19.9 | 159,157 | Common Stock |
| Yang Li | Exec. Vice President, Research | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2026 | 2,500 | 17,209 | - | - | Common Stock | |
| Yang Li | Exec. Vice President, Research | Sale of securities on an exchange or to another person at price $ 19.86 per share. | 02 Jan 2026 | 1,118 | 16,091 | - | 19.9 | 22,209 | Common Stock |
| Yang Li | Exec. Vice President, Research | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2026 | 2,500 | 0 | - | - | Restricted Stock Units | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 8.11 per share. | 15 Dec 2025 | 1,553 | 8,577 | - | 8.1 | 12,595 | Common Stock |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 8.11 per share. | 15 Dec 2025 | 1,666 | 14,709 | - | 8.1 | 13,511 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 17.35 per share. | 04 Dec 2025 | 2,475 | 854,957 | - | 17.3 | 42,934 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.54 per share. | 04 Dec 2025 | 14,503 | 869,460 | - | 19.5 | 283,402 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 17.35 per share. | 04 Dec 2025 | 2,791 | 965,509 | - | 17.3 | 48,415 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 19.54 per share. | 04 Dec 2025 | 16,381 | 981,890 | - | 19.5 | 320,099 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 12.65 per share. | 13 Nov 2025 | 167,307 | 962,718 | - | 12.7 | 2,116,434 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 12.65 per share. | 13 Nov 2025 | 148,150 | 852,482 | - | 12.7 | 1,874,098 | Common Stock |
| Andrew Pedrum Maleki | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Nov 2025 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 8.06 per share. | 13 Jun 2025 | 400 | 7,024 | - | 8.1 | 3,224 | Common Stock |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 8.06 per share. | 13 Jun 2025 | 400 | 13,043 | - | 8.1 | 3,224 | Common Stock |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Christopher Y. Chai | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Anna Berkenblit | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Shao-Lee Lin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| David J. Woodhouse | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Mace Rothenberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Mary Haak-Frendscho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 May 2025 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2025 | 75,000 | 75,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2025 | 25,000 | 25,000 | - | - | Restricted Stock Unit | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2025 | 8,750 | 8,750 | - | - | Restricted Stock Unit | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2025 | 26,250 | 26,250 | - | - | Option (right to buy) | |
| Tim Kutzkey | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2025 | 2,666 | 2,666 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Mar 2025 | 1,603 | 1,603 | - | - | Series B Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 24 Mar 2025 | 1,603 | 0 | - | - | Series B Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 24 Mar 2025 | 5,712 | 0 | - | - | Series C Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 24 Mar 2025 | 5,712 | 0 | - | - | Series D Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Mar 2025 | 1,474 | 1,474 | - | - | Series A Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 24 Mar 2025 | 1,474 | 0 | - | - | Series A Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2025 | 100,000 | 100,000 | - | - | Option (right to buy) | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2025 | 35,000 | 35,000 | - | - | Option (right to buy) | |
| Yang Li | Exec. Vice President, Research | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Jan 2025 | 2,500 | 14,188 | - | - | Common Stock | |
| Yang Li | Exec. Vice President, Research | Sale of securities on an exchange or to another person at price $ 17.37 per share. | 02 Jan 2025 | 843 | 13,345 | - | 17.4 | 14,643 | Common Stock |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 5.67 per share. | 14 Jun 2024 | 400 | 5,824 | - | 5.7 | 2,268 | Common Stock |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 5.67 per share. | 14 Jun 2024 | 400 | 10,888 | - | 5.7 | 2,268 | Common Stock |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Christopher Y. Chai | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Anna Berkenblit | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Shao-Lee Lin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| David J. Woodhouse | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Mace Rothenberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Tim Kutzkey | Director, Ten Percent Owner | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | ||
| Mary Haak-Frendscho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Jun 2024 | 1,333 | 1,333 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2024 | 43,000 | 43,000 | - | - | Option (right to buy) | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 May 2024 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Apr 2024 | 43,000 | 43,000 | - | - | Option (right to buy) | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Apr 2024 | 5,000 | 5,000 | - | - | Restricted Stock Unit | |
| Yang Li | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Apr 2024 | 10,000 | 10,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 5,712 | 5,712 | - | - | Series D Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 1,474 | 1,474 | - | - | Common Stock | |
| Craig C. Parker | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 1,474 | 1,474 | - | - | Series A Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 1,603 | 1,603 | - | - | Series B Common Stock Warrant (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 5,712 | 5,712 | - | - | Series C Common Stock Warrant (right to buy) | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 98,870 | 98,870 | - | - | Series B Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 111,656 | 111,656 | - | - | Series B Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 352,225 | 352,225 | - | - | Series C Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 352,225 | 352,225 | - | - | Series D Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 397,773 | 397,773 | - | - | Series D Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 397,773 | 397,773 | - | - | Series C Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 15.50 per share. | 04 Apr 2024 | 90,897 | 294,767 | - | 15.5 | 1,408,904 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 15.50 per share. | 04 Apr 2024 | 102,651 | 332,885 | - | 15.5 | 1,591,091 | Common Stock |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 90,897 | 90,897 | - | - | Series A Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Apr 2024 | 102,651 | 102,651 | - | - | Series A Common Warrants | |
| Tim Kutzkey | Director, Ten Percent Owner | 04 Apr 2024 | 102,651 | 326,992 | - | 15.5 | 1,591,091 | Common Stock | |
| Tim Kutzkey | Director, Ten Percent Owner | 04 Apr 2024 | 90,897 | 289,549 | - | 15.5 | 1,408,904 | Common Stock | |
| C. Craig Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Jan 2024 | 33 | 33 | - | - | Option (right to buy) | |
| Li Yang | Exec. Vice President, Research | Grant, award, or other acquisition of securities at price $ 5.67 per share. | 15 Dec 2023 | 2,085 | 2,085 | - | 5.7 | 11,822 | Common Stock |
| C. Parker Craig | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 5.67 per share. | 15 Dec 2023 | 2,046 | 2,046 | - | 5.7 | 11,601 | Common Stock |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.38 per share. | 15 Jun 2023 | 25,000 | 34,578 | - | 0.4 | 9,500 | Common Stock |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.38 per share. | 15 Jun 2023 | 17,638 | 27,216 | - | 0.4 | 6,702 | Common Stock |
| Eric H. Bjerkholt | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Christopher Y. Chai | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Anna Berkenblit | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Shao-Lee Lin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| David J. Woodhouse | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Mace Rothenberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Tim Kutzkey | Director, Ten Percent Owner | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | ||
| Mary Haak-Frendscho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 May 2023 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2023 | 405,000 | 405,000 | - | - | Option (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Feb 2023 | 125,000 | 125,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.41 per share. | 15 Dec 2022 | 9,578 | 9,578 | - | 0.4 | 3,927 | Common Stock |
| Geertrui Trudy Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.41 per share. | 15 Dec 2022 | 9,578 | 32,412 | - | 0.4 | 3,927 | Common Stock |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.41 per share. | 15 Dec 2022 | 9,578 | 229,138 | - | 0.4 | 3,927 | Common Stock |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 2,065 | 2,065 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 35,987 | 0 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 2,065 | 0 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 181,270 | 0 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 315,310 | 0 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 35,987 | 35,987 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 315,310 | 315,310 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 181,270 | 181,270 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 10,427 | 10,427 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 24,587 | 24,587 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 1,760 | 1,760 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 24,587 | 0 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 10,427 | 0 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 26,220 | 0 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 10 Oct 2022 | 1,760 | 0 | - | - | Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Oct 2022 | 26,220 | 26,220 | - | - | Option (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 01 Jul 2022 | 5,562 | 0 | - | - | Option (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 500 | 500 | - | - | Option (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 5,562 | 5,562 | - | - | Option (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Jul 2022 | 29,567 | 29,567 | - | - | Option (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Sale or transfer of securities back to the company at price $ 0.00 per share. | 01 Jul 2022 | 29,567 | 0 | - | - | Option (right to buy) | |
| Christopher Y. Chai | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Anna Berkenblit | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Shao-Lee Lin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| David J. Woodhouse | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Mace Rothenberg | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Tim Kutzkey | Director, Ten Percent Owner | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | ||
| Mary Haak-Frendscho | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2022 | 20,000 | 20,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 370,000 | 370,000 | - | - | Stock Option (right to buy) | |
| Geertrui Trudy Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 125,000 | 125,000 | - | - | Option Grant (right to buy) | |
| Wen-Chen Yeh | Chief Scientific Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2022 | 125,000 | 125,000 | - | - | Option (right to buy) | |
| Craig C. Parker | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2021 | 183,335 | 183,335 | - | - | Stock Option (right to buy) | |
| Geertrui Vanhove | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Aug 2021 | 36,647 | 36,647 | - | - | Employee Stock Option (right to buy) |